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1. 发明申请

WO2009077896A2 FORMULATION AND PRODUCTS FOR PROMOTING SKIN CLEANLINESS AND HEALTH 审中-公开
标题翻译：促进皮肤清洁和健康的配方和产品
公开(公告)号：WO2009077896A2
公开(公告)日：2009-06-25
申请号：PCT/IB2008054876
申请日：2008-11-20
申请人： KIMBERLY CLARK CO , WENZEL SCOTT W , KOENIG DAVID WILLIAM , HOFFMAN DOUGLAS R , KRAUTKRAMER CANDACE DYAN , THOMAS BRIAN , MOCADLO CHERYL , MAGIN CHELSEA
发明人： WENZEL SCOTT W , KOENIG DAVID WILLIAM , HOFFMAN DOUGLAS R , KRAUTKRAMER CANDACE DYAN , THOMAS BRIAN , MOCADLO CHERYL , MAGIN CHELSEA
IPC分类号： A61L15/42 , A61L15/16 , A61L15/22
CPC分类号： A61L15/34 , A61F13/8405 , A61F2013/51117 , A61F2013/8455
摘要： The present disclosure generally relates to a formulation. More particularly, the formulation may be applied to skin and/or used in combination with a personal care product to improve absorbance and leakage control of the personal care product, and to promote a more positive feel and comfort through improved skin cleanliness and health.
摘要翻译：本公开总体涉及一种制剂。更特别地，所述制剂可以施用于皮肤和/或与个人护理产品组合使用，以改善个人护理产品的吸光度和渗漏控制，并通过改善皮肤清洁度和健康促进更积极的感觉和舒适感。

2. 发明申请

WO2009083911A3 ULTRASONIC TREATMENT CHAMBER FOR PARTICLE DISPERSION INTO FORMULATIONS 审中-公开
标题翻译：用于颗粒分散到配方中的超声波处理室
公开(公告)号：WO2009083911A3
公开(公告)日：2009-10-15
申请号：PCT/IB2008055520
申请日：2008-12-23
申请人： KIMBERLY CLARK CO , JANSSEN ROBERT ALLEN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , EHLERT THOMAS DAVID , ZHUANG SHIMING , AHLES JOHN GLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE
发明人： JANSSEN ROBERT ALLEN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , EHLERT THOMAS DAVID , ZHUANG SHIMING , AHLES JOHN GLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE
IPC分类号： B01F13/02 , B01F3/12 , B01J19/10
CPC分类号： B01F11/0258 , B01F3/1242 , B01F5/10 , B01F2215/045 , B01F2215/0454
摘要： An ultrasonic mixing system having a particulate dispensing system to dispense particulates into a treatment chamber and the treatment chamber in which particulates can be mixed with one or more formulations is disclosed. Specifically, the treatment chamber has an elongate housing through which a formulation and particulates flow longitudinally from an inlet port to an outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation and particulates within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation and particulates being mixed in the chamber.
摘要翻译：公开了一种超声混合系统，其具有用于将微粒分配到处理室中的微粒分配系统和其中微粒可以与一种或多种配方混合的处理室。具体而言，处理室具有细长的外壳，制剂和颗粒通过该外壳纵向地从入口端口流向出口端口。细长的超声波导组件在外壳内延伸并且可以预定的超声频率操作以超声地激励外壳内的制剂和颗粒。波导组件的细长超声波喇叭筒至少部分地设置在入口和出口端口的中间，并且具有多个分立的搅动构件，该喇叭状件与喇叭口接触并从喇叭口横向向外延伸，入口和出口之间以纵向间隔的关系与彼此。喇叭和搅动构件被构造和布置成用于搅动构件相对于喇叭以预定频率进行动态运动并且以与预定频率相对应的搅动构件的超声空化模式进行操作，并且制剂和颗粒在室。

3. 发明申请

WO2008001240A3 TRANSDERMAL DELIVERY OF OLEOCANTHAL FOR RELIEF OF INFLAMMATION 审中-公开
标题翻译：透皮释放的松质透皮释放
公开(公告)号：WO2008001240A3
公开(公告)日：2008-02-21
申请号：PCT/IB2007052071
申请日：2007-06-01
申请人： KIMBERLY CLARK CO , FELDKAMP JOSEPH R , KOENIG DAVID WILLIAM , WENZEL SCOTT W , JOSEPH WAEL R
发明人： FELDKAMP JOSEPH R , KOENIG DAVID WILLIAM , WENZEL SCOTT W , JOSEPH WAEL R
IPC分类号： A61K31/216 , A61K9/00 , A61K9/70 , A61K47/26 , A61K47/34 , A61P17/00
CPC分类号： A61K9/0014 , A61K9/12 , A61K9/7038 , A61K31/216 , A61K47/10
摘要： The present disclosure generally relates to compositions for reducing inflammation, and more particularly, to compositions comprising oleocanthal. The oleocanthal- containing compositions are particularly suitable for transdermal delivery. The compositions may also be used in combination with personal care products, such as wipes and absorbent articles, and may be incorporated into transdermal patches.
摘要翻译：本公开总体上涉及用于减轻炎症的组合物，并且更具体地涉及包含ole吨油的组合物。含ole油的组合物特别适用于透皮递送。该组合物也可以与个人护理产品如擦巾和吸湿用品结合使用，并且可以掺入透皮贴剂中。

4. 发明申请

WO2010070502A2 LIQUID SURFACTANT COMPOSITIONS THAT ADHERE TO SURFACES AND SOLIDIFY AND SWELL IN THE PRESENCE OF WATER AND ARTICLES USING THE SAME 审中-公开
标题翻译：表面和表面水溶性表面活性剂组合物和水溶性物质的使用
公开(公告)号：WO2010070502A2
公开(公告)日：2010-06-24
申请号：PCT/IB2009055270
申请日：2009-11-22
申请人： KIMBERLY CLARK CO , SEIDLING JEFFERY RICHARD , WENZEL SCOTT W , KOENIG DAVID WILLIAM
发明人： SEIDLING JEFFERY RICHARD , WENZEL SCOTT W , KOENIG DAVID WILLIAM
IPC分类号： C11D1/65
CPC分类号： A61F13/475 , A61B42/00 , A61B46/10 , A61B46/40 , A61L15/18 , A61L15/48 , A61L15/60 , C11D1/65
摘要： A liquid surfactant composition includes at least one anionic surfactant and at least one cationic surfactant. The combination of surfactants is formulated to provide a liquid composition that swells in the presence of water or body fluids, becomes a moldable solid in the presence of an excess of water, and adheres to surfaces. In addition, the liquid surfactant composition may be incorporated into or onto a substrate, such as an absorbent substrate, a fabric or cloth substrate, a tissue substrate, or a protective garment substrate.
摘要翻译：液体表面活性剂组合物包括至少一种阴离子表面活性剂和至少一种阳离子表面活性剂将表面活性剂的组合配制成提供在水或体液存在下溶胀的液体组合物，在过量的水存在下变成可成型的固体，并粘附在表面上。此外，液体表面活性剂组合物可以结合到基材上或其上，例如吸收性基材，织物或布基材，组织基材或保护性服装基材。

5. 发明申请

WO2009083910A3 ULTRASONIC TREATMENT CHAMBER FOR PREPARING EMULSIONS 审中-公开
标题翻译：用于制备乳液的超声处理室
公开(公告)号：WO2009083910A3
公开(公告)日：2009-10-15
申请号：PCT/IB2008055518
申请日：2008-12-23
申请人： KIMBERLY CLARK CO , JANSSEN ROBERT ALLEN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , EHLERT THOMAS DAVID , ZHUANG SHIMING , AHLES JOHN GLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE
发明人： JANSSEN ROBERT ALLEN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , EHLERT THOMAS DAVID , ZHUANG SHIMING , AHLES JOHN GLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE
IPC分类号： B01F13/02 , B01F3/08 , B01J19/08
CPC分类号： B01F3/0819 , B01F11/0258 , B01F2215/045 , B01F2215/0454 , B01J19/006 , B01J19/0066 , B01J19/24 , Y10T137/2185 , Y10T137/2196
摘要： An ultrasonic mixing system having a treatment chamber in which at least two separate phases can be mixed to prepare an emulsion is disclosed. Specifically, at least one phase is a dispersed phase and one phase in a continuous phase. The treatment chamber has an elongate housing through which the phases flow longitudinally from a first inlet port and a second inlet port, respectively, to an outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the phases within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the phases being mixed in the chamber.
摘要翻译：公开了一种具有处理室的超声波混合系统，其中至少两个分开的相可以混合以制备乳液。具体地说，至少一相是连续相中的分散相和一相。处理室具有细长的壳体，相位分别从第一入口端口和第二入口端口纵向流到其出口端。细长的超声波波导组件在壳体内延伸并且可以预定的超声波频率操作以对壳体内的相超声波激励。波导组件的细长的超声波喇叭至少部分地设置在入口和出口的中间，并且具有多个离散的搅拌构件，其与入口和出口端口处的喇叭的横向外部接触并向外延伸，与纵向间隔开的关系彼此。喇叭和搅拌构件被构造和布置成用于搅动构件相对于喇叭以预定频率的动态运动，并且以与预定频率相对应的搅拌构件的超声空化模式操作，并且相在腔室中混合。

6. 发明申请

WO2009083906A2 ULTRASONIC TREATMENT CHAMBER FOR INCREASING THE SHELF LIFE OF FORMULATIONS 审中-公开
标题翻译：超声波治疗室用于增加制剂寿命
公开(公告)号：WO2009083906A2
公开(公告)日：2009-07-09
申请号：PCT/IB2008055514
申请日：2008-12-23
申请人： KIMBERLY CLARK CO , KOENIG DAVID WILLIAM , AHLES JOHN GLEN , EHLERT THOMAS DAVID , JANSSEN ROBERT ALLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE , WENZEL SCOTT W , ZHUANG SHIMING
发明人： KOENIG DAVID WILLIAM , AHLES JOHN GLEN , EHLERT THOMAS DAVID , JANSSEN ROBERT ALLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE , WENZEL SCOTT W , ZHUANG SHIMING
CPC分类号： B01D19/0094 , B01D19/0078
摘要： An ultrasonic treatment system having a treatment chamber for treating a formulation to increase the shelf life thereof. In one embodiment, the shelf life is produced by degassing the formulation using the treatment chamber. Specifically, the treatment chamber has an elongate housing through which a formulation flows longitudinally from an inlet port to a first outlet port and a second outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation being treated in the chamber.
摘要翻译：一种超声处理系统，其具有用于处理制剂以增加其保质期的处理室。在一个实施方案中，通过使用处理室对制剂进行脱气而产生保质期。具体地说，处理室具有细长的外壳，制剂通过该外壳纵向从入口端口流向第一出口和第二出口。细长的超声波波导组件在壳体内延伸并且可以预定的超声频率操作以超声波地激励壳体内的配方。波导组件的细长的超声波喇叭至少部分地设置在入口和出口的中间，并且具有多个离散的搅拌构件，其与入口和出口端口处的喇叭的横向外部接触并向外延伸，与纵向间隔开的关系彼此。喇叭和搅拌构件被构造和布置成用于以预定频率相对于喇叭的动态运动，并且以对应于预定频率的搅拌构件的超声空化模式和在腔室中处理的配方进行操作。

7. 发明申请

WO2011045681A3 CARBOHYDRATE ENTRAPPED ACTIVE AGENT DELIVERY COMPOSITION AND ARTICLES USING THE SAME 审中-公开
标题翻译：碳水化合物加入活性剂输送组合物及使用其的制品
公开(公告)号：WO2011045681A3
公开(公告)日：2011-07-14
申请号：PCT/IB2010053931
申请日：2010-09-01
申请人： KIMBERLY CLARK CO , WENZEL SCOTT W , KOENIG DAVID WILLIAM , SEIDLING JEFFERY RICHARD , CHEN MICHAEL MEIHAN
发明人： WENZEL SCOTT W , KOENIG DAVID WILLIAM , SEIDLING JEFFERY RICHARD , CHEN MICHAEL MEIHAN
IPC分类号： A61K9/70 , A61K47/36 , A61K47/38 , A61P17/00 , A61P31/04
CPC分类号： A61K31/05 , A01N31/08 , A61K9/5015 , A61L15/42 , A01N25/10
摘要： Delivery compositions and substrates for imparting a volatile active agent to a surface are disclosed herein. To achieve the delivery of the volatile component, a delivery composition of a carbohydrate matrix and a volatile component is incorporated into the carbohydrate matrix to stabilize the volatile for extended periods of time. The delivery composition further comprises a self-generating expelling agent to expel the volatile component onto the contaminated surface or skin upon addition of a triggering agent.
摘要翻译：本文公开了将挥发性活性剂赋予表面的输送组合物和底物。为了实现挥发性组分的递送，将碳水化合物基质和挥发性组分的递送组合物掺入碳水化合物基质中以使挥发物稳定地延长时间。递送组合物还包括自发生排出剂，以在添加触发剂时将挥发性组分排出到污染的表面或皮肤上。

8. 发明申请

WO2011045682A2 ACTIVE AGENT CONTAINING POLYMER NETWORK DELIVERY COMPOSITION AND ARTICLES USING THE SAME 审中-公开
标题翻译：含有聚合物网络输送组合物的活性剂和使用该组合物的制品
公开(公告)号：WO2011045682A2
公开(公告)日：2011-04-21
申请号：PCT/IB2010053932
申请日：2010-09-01
申请人： KIMBERLY CLARK CO , KOENIG DAVID WILLIAM , WENZEL SCOTT W , SEIDLING JEFFERY RICHARD , CHEN MICHAEL MEIHAN
发明人： KOENIG DAVID WILLIAM , WENZEL SCOTT W , SEIDLING JEFFERY RICHARD , CHEN MICHAEL MEIHAN
IPC分类号： A61K9/70 , A61K47/30 , A61K47/36 , A61K47/38 , A61P17/00 , A61P31/04
CPC分类号： A61K31/05 , A61K8/0208 , A61K8/347 , A61K8/8117 , A61K9/7007 , A61L15/44 , A61L15/46 , A61Q17/005 , A61Q19/00 , A61Q19/10
摘要： Delivery compositions and substrates for imparting a volatile active agent to a surface are disclosed herein. To achieve the delivery of the volatile component, a delivery composition of a polymer network and a volatile component incorporated into the polymer network to stabilize the volatile for extended periods of time. The delivery composition may also be present on a substantially dry substrate to deliver the active agent. The dry substrate may be selected from facial tissue, bath tissue, paper towel, or dinner napkin. The substantially dry substrate may also be reusable.
摘要翻译：本文公开了将挥发性活性剂赋予表面的输送组合物和底物。为了实现挥发性组分的输送，聚合物网络的输送组合物和并入聚合物网络中的挥发性组分以稳定挥发性物质延长的时间段。递送组合物也可以存在于基本干燥的基质上以递送活性剂。干基质可以选自面巾纸，浴巾，纸巾或餐巾。基本干燥的基底也可以是可重复使用的。

9. 发明申请

WO2010070483A3 SUBSTRATES PROVIDING MULTIPLE RELEASES OF ACTIVE AGENTS 审中-公开
标题翻译：提供有效代理许可的基础
公开(公告)号：WO2010070483A3
公开(公告)日：2010-09-02
申请号：PCT/IB2009055106
申请日：2009-11-16
申请人： KIMBERLY CLARK CO , HOFFMAN DOUGLAS ROBERT , SMILTNEEK ANDREA JO , CARNEY SARA ANN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , SEIDLING JEFFERY RICHARD
发明人： HOFFMAN DOUGLAS ROBERT , SMILTNEEK ANDREA JO , CARNEY SARA ANN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , SEIDLING JEFFERY RICHARD
IPC分类号： B32B27/00 , A61F13/02 , A61L15/44 , A61L15/48
CPC分类号： A61K9/7007 , A61K9/0024 , A61K31/00 , A61L15/22 , A61L15/44 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/61
摘要： The present disclosure comprises a polymeric substrate that provides multiple releases of active agents. A substrate for multiple phase delivery of active agents is provided having a first polymer matrix layer having a first active agent disposed therein, a second polymer matrix layer having a second active agent disposed therein, and a coacervate layer disposed between the first polymer matrix layer and the second polymer matrix layer. Selected first and second active agents are included in the first and second polymer matrices such that as the first and second polymer matrices dissolve, the active agents are released. Multiple phase active agent release is achieved by constructing multiple layers of a polymer matrix containing an active agents formed with polymers having different solubility characteristics or with active agents at different concentration levels.
摘要翻译：本公开内容包括提供活性剂多次释放的聚合物基质。提供一种用于多相递送活性剂的底物，其具有设置在其中的第一活性剂的第一聚合物基质层，其中设置有第二活性剂的第二聚合物基质层和设置在第一聚合物基质层和第二聚合物基质层之间的凝聚层，第二聚合物基质层。选择的第一和第二活性剂包括在第一和第二聚合物基质中，使得当第一和第二聚合物基质溶解时，活性剂被释放。通过构建多层含有由不同溶解度特征的聚合物形成的活性剂或具有不同浓度水平的活性剂形成的聚合物基质来实现多相活性剂释放。

10. 发明申请

WO2009083909A2 ULTRASONIC TREATMENT CHAMBER FOR PREPARING ANTIMICROBIAL FORMULATIONS 审中-公开
标题翻译：用于制备抗微生物制剂的超声处理室
公开(公告)号：WO2009083909A2
公开(公告)日：2009-07-09
申请号：PCT/IB2008055517
申请日：2008-12-23
申请人： KIMBERLY CLARK CO , JANSSEN ROBERT ALLEN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , EHLERT THOMAS DAVID , ZHUANG SHIMING , AHLES JOHN GLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE
发明人： JANSSEN ROBERT ALLEN , WENZEL SCOTT W , KOENIG DAVID WILLIAM , EHLERT THOMAS DAVID , ZHUANG SHIMING , AHLES JOHN GLEN , RASMUSSEN PAUL WARREN , ROFFERS STEVE
CPC分类号： B01F11/0258 , B01F2215/0009 , B01F2215/045 , B01F2215/0454
摘要： An ultrasonic mixing system having a treatment chamber in which antimicrobial agents, particularly, hydrophobic antimicrobial agents, can be mixed with one or more formulations is disclosed. Specifically, the treatment chamber has an elongate housing through which a formulation and antimicrobial agents flow longitudinally from a first inlet port and a second inlet port to an outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation and antimicrobial agents within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation and antimicrobial agents being mixed in the chamber.
摘要翻译：公开了一种具有处理室的超声波混合系统，其中抗微生物剂，特别是疏水性抗微生物剂可以与一种或多种制剂混合。具体而言，处理室具有细长壳体，制剂和抗微生物剂通过该壳体纵向地从第一入口端口和第二入口端口流向其出口端口。细长的超声波导组件在外壳内延伸并且可以预定的超声频率操作以超声地激励外壳内的制剂和抗微生物剂。波导组件的细长超声波喇叭筒至少部分地设置在入口和出口端口的中间，并且具有多个分立的搅动构件，该喇叭状件与喇叭口接触并从喇叭口横向向外延伸，入口和出口之间以纵向间隔的关系与彼此。喇叭和搅动构件被构造和布置成用于搅动构件相对于喇叭以预定频率进行动态运动并且以与预定频率相对应的搅动构件的超声空化模式进行操作，并且制剂和抗微生物剂被混入房间。

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