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1. 发明申请

WO2003037083A1 SYSTEMS AND METHODS FOR FREEZING AND STORING BIOPHARMACUETICAL MATERIAL 审中-公开
标题翻译：用于冷冻和储存生物材料的系统和方法
公开(公告)号：WO2003037083A1
公开(公告)日：2003-05-08
申请号：PCT/US2002/035137
申请日：2002-11-01
申请人： INTEGRATED BIOSYSTEMS, INC. , VOUTE, Nicolas , LOK, Maxime , LEONARD, Leonidas, Cartwright , HUGHES, Timothy, Gerard , WISNIEWSKI, Richard
发明人： VOUTE, Nicolas , LOK, Maxime , LEONARD, Leonidas, Cartwright , HUGHES, Timothy, Gerard , WISNIEWSKI, Richard
IPC分类号： A01N1/00
CPC分类号： F25D31/001 , A01N1/02 , A01N1/0257 , A01N1/0263 , A23L3/364 , A23L3/365 , A61M1/0277 , A61M1/0281 , F25B2600/07 , F25D25/00 , F25D2331/8014 , F25D2400/20 , F25D2400/30 , F25D2500/02
摘要： The present invention provides a system for freezing, thawing, and storing biopharmaceutical materials which includes a flexible container, a conduit, and a temperature control unit. The flexible container is adapted to receive a biopharmaceutical material therein for freezing, thawing, and storing. The container is formed of a first substantially flat sheet of flexible material joined together by a seam with a second substantially flat sheet of flexible material so as to lie substantially flat when empty. The container fully encloses an interior portion for receiving the biopharmaceutical material. Also, the container is configured to form a three dimensional shape when filled with the biopharmaceutical material, wherein the three dimensional shape has a first side and a second side opposite the first side. The conduit is connected to the flexible container with the outside of the container being in fluid communication with the interior portion via the conduit. The temperature control unit includes a first surface and a second surface facing the first surface and the temperature control unit is configured to receive the flexible container therein, when the container is filled with the biopharmaceutical material. The container conforms to the shape of the interior of the temperature control unit and the first side and the second side of the container contact the first surface and the second surface of the temperature control unit. The first surface and/or the second surface of temperature control unit include heat transfer surface(s).
摘要翻译：本发明提供一种用于冷冻，解冻和储存包括柔性容器，导管和温度控制单元的生物药物材料的系统。柔性容器适于在其中容纳生物药物用于冷冻，解冻和储存。容器由具有第二基本平坦的柔性材料片的接缝连接在一起的第一基本平坦的柔性材料片形成，以便在空的时基本平坦。容器完全包围用于接收生物药物材料的内部部分。此外，容器被配置为当填充有生物药物材料时形成三维形状，其中三维形状具有与第一侧相对的第一侧和第二侧。导管连接到柔性容器，容器的外部经由导管与内部部分流体连通。温度控制单元包括面向第一表面的第一表面和第二表面，并且温度控制单元构造成当容器填充有生物药物材料时将柔性容器接纳在其中。容器符合温度控制单元的内部形状，并且容器的第一侧和第二侧接触温度控制单元的第一表面和第二表面。温度控制单元的第一表面和/或第二表面包括传热表面。

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