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    • 3. 发明申请
    • SHEAR WAVE GENERATION METHOD, SHEAR WAVE IMAGING METHOD AND THERMAL MAPPING OR TREATING METHOD UTILIZING SUCH A GENERATION METHOD AND INSTALLATION FOR GENERATING AT LEAST ONE SHEAR WAVE
    • 剪切波生成方法,剪切波形成像方法和使用这种生成方法的热绘制或处理方法和用于产生至少一个剪切波的安装
    • WO2015128409A1
    • 2015-09-03
    • PCT/EP2015/054002
    • 2015-02-26
    • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)UNIVERSITÉ CLAUDE BERNARD LYON 1
    • CATHELINE, StefanSOUCHON, RémiZORGANI, AliCHAPELON, Jean-Yves
    • A61B8/00A61B8/08G01S7/52G01S15/89
    • A61B8/485A61B5/0066A61B5/015A61B5/055A61B8/4416A61B8/4466A61B8/4477A61B8/4488G01S7/52022G01S15/8918G01S15/8977
    • This method for generating at least one shear wave in a target region of a soft solid, includes at least the following steps: a) generating (1002, 1004, 1006) at least one shear wave (SW 1 , SW 2 , SW 3 ) in the target region; b) detecting (1003, 1005, 1007) a propagation pattern (P1) of the least one shear wave in the target region; c) proceeding (1008) to a time reversal of the detected propagation pattern; and d) submitting (1011) the target region to an inverted excitation set of forces based on the temporally inverted propagation pattern. Step a) (1002, 1004) is implemented by generating at least two shear waves with at least a first source of shear waves (SW 1 , SW' 1 ) and at least a second source of shear waves (SW 2 , SW' 2 ). Step b) is implemented with a detector unit (10) which includes a row (10) of ultrasonic transducers (Ti) aligned on a first direction (X10) perpendicular to a detection direction (Di) of each ultrasonic transducer or a single ultrasonic transducer movable along a first direction (X) perpendicular to its detection direction. During step b), a first propagation pattern (P1) is detected (1003) when only the first source is active and a second propagation pattern (P2) is detected (1005) when only the second source is active. During step c), the first and second propagation patterns (P1, P2) are time-reversed (1008, 1009) independently from each other in order to generate, respectively, a first reverse excitation scheme (Ρ1') and a second reverse excitation scheme (Ρ2'). At step d), the first source is controlled (1011) with the first reverse excitation scheme (Ρ1') to generate at least a first modified shear wave (SW' 1 ) and, simultaneously, the second source is controlled with the second reverse excitation scheme (Ρ2') to generate at least a second modified shear wave (SW' 2 ), whereas the shear waves are focused at a given point of the target region.
    • 用于在软固体的目标区域中产生至少一个剪切波的该方法至少包括以下步骤:a)产生目标中的至少一个剪切波(SW1,SW2,SW3)(1002,1004,1006) 地区; b)检测(1003,1005,1007)目标区域中的至少一个剪切波的传播模式(P1); c)进行(1008)到检测到的传播模式的时间反转; 以及d)基于时间反转的传播模式将目标区域(1011)提交给反向激励力集合。 步骤a)(1002,1004)通过产生具有至少第一剪切波源(SW1,SW'1)和至少第二切割源(SW2,SW'2)的至少两个剪切波来实现。 步骤b)由检测器单元(10)实现,检测器单元(10)包括在垂直于每个超声换能器的检测方向(Di)的第一方向(X10)上排列的超声波换能器(Ti)的行(10)或单个超声换能器 沿着与其检测方向垂直的第一方向(X)可移动。 在步骤b)期间,当仅第二源处于活动状态时仅检测到第一传播模式(P2)被检测到第一传播模式(P2)(1005))时,检测到第一传播模式(P1)(1003)。 在步骤c)期间,第一和第二传播模式(P1,P2)彼此独立地时间反转(1008,1009),以分别产生第一反向激励方案(Ρ1')和第二反向激励 方案(Ρ2')。 在步骤d),用第一反向激励方案(Ρ1')控制第一源(1011)以产生至少第一修改剪切波(SW'1),并且同时第二源被控制在第二反向 激励方案(Ρ2')以产生至少第二修改剪切波(SW'2),而剪切波被聚焦在目标区域的给定点。
    • 6. 发明申请
    • SHEAR WAVE IMAGING METHOD AND INSTALLATION FOR COLLECTING INFORMATION ON A SOFT SOLID
    • 剪切波形成像方法和软件收集信息的安装
    • WO2015004224A1
    • 2015-01-15
    • PCT/EP2014/064794
    • 2014-07-10
    • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)UNIVERSITE CLAUDE BERNARD LYON 1
    • CATHELINE, StefanCHAPELON, Jean-YvesSOUCHON, RémiGRASLAND-MONGRAIN, PolLAFON, Cyril
    • G01R33/563A61B5/05A61B5/053A61B8/08
    • A61B5/0051A61B5/05A61B5/0536A61B5/055A61B8/485G01R33/56358
    • This shear wave imaging method, for collecting information on a target region (R) of a soft solid (S), comprises at least the steps a) of generating at least one shear wave (SW) in the target region, and b) of detecting a propagation pattern of the shear wave in the target region. Step a) is realized by applying to particles of the target region (R) some Lorentz forces resulting from an electric field (E) and from a magnetic field (B). At least one of the electric field (E) and the magnetic field (B) is variable in time, with a central frequency (f o ) between 1 Hz and 10 kHz. Alternatively, both the electric and magnetic fields (E, B) are variable in time, with a central difference frequency (∆f o ) between 1 Hz and 10 kHz. The shear wave imaging installation comprises a first system (4, 7) for generating at least one shear wave (SW) in the target region (R) and a second system (10) for detecting a propagation pattern of the shear wave. The first system includes first means (4) to apply an electric field (E) through the target region (R) and second means (7) to apply a magnetic field (B) through the target region. The first and second means are configured to apply to particles of the target region some Lorentz forces resulting from the electric field (E) and the magnetic field (B), where at least one of these fields is a quantity variable in time, with a central frequency (f o ) between 1 Hz and 10 kHz, or both fields are quantities variable in time, with a central difference frequency (∆f o ) between 1 Hz and 10 kHz.
    • 用于收集关于软固体(S)的目标区域(R)的信息的该剪切波成像方法至少包括在目标区域中产生至少一个剪切波(SW)的步骤a),以及b) 检测目标区域中的剪切波的传播模式。 步骤a)通过向目标区域(R)的粒子施加一些由电场(E)和磁场(B)产生的洛伦兹力来实现。 电场(E)和磁场(B)中的至少一个在时间上是可变的,中心频率(fo)在1Hz和10kHz之间。 或者,电场和磁场(E,B)在时间上是可变的,中心差频率(Δfo)在1Hz和10kHz之间。 剪切波成像设备包括用于在目标区域(R)中产生至少一个剪切波(SW)的第一系统(4,7)和用于检测剪切波的传播模式的第二系统(10)。 第一系统包括通过目标区域(R)和第二装置(7)施加电场(E)的第一装置(4),以通过目标区域施加磁场(B)。 第一和第二装置被配置为向目标区域的颗粒施加由电场(E)和磁场(B)产生的一些洛伦兹力,其中这些场中的至少一个是时间上的变量,其中 1 Hz至10 kHz之间的中心频率(fo),或两个场均为时间可变的量,中心频率(Δfo)介于1 Hz和10 kHz之间。