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1. 发明申请

WO2003037303A1 SPRAY DRYING METHODS AND COMPOSITIONS THEREOF 审中-公开
标题翻译：喷雾干燥方法及其组合物
公开(公告)号：WO2003037303A1
公开(公告)日：2003-05-08
申请号：PCT/US2002/034909
申请日：2002-10-31
申请人： INHALE THERAPEUTIC SYSTEMS, INC. , SNYDER, Herman, E. , VOSBERG, Michael, J. , VARGA, Christopher, M.
发明人： SNYDER, Herman, E. , VOSBERG, Michael, J. , VARGA, Christopher, M.
IPC分类号： A61K9/14
CPC分类号： A61K9/0075 , A61K9/1617 , A61K9/1623 , A61K31/58 , B01D1/18 , B01D1/20 , B01J2/04
摘要： A method and apparatus are provided for atomizing a liquid under dispersal conditions suitable for spray drying at a commercial plant scale. In one embodiment, a liquid atomizer has a structural body adapted for connection with a spray dryer and a plurality of atomizing nozzles. Each of the atomizing nozzles includes a liquid nozzle adapted to disperse a supply of liquid and a gas nozzle adapted to disperse a supply of gas. In another embodiment, a process for producing a powder blend of at least two target substances in a single processing step is provided.
摘要翻译：提供了一种方法和装置，用于在适用于商业植物规模的喷雾干燥的分散条件下使液体雾化。在一个实施例中，液体雾化器具有适于与喷雾干燥器和多个雾化喷嘴连接的结构体。每个雾化喷嘴包括适于分散液体供应的液体喷嘴和适于分散气体供应的气体喷嘴。在另一个实施方案中，提供了在单个加工步骤中制备至少两种目标物质的粉末共混物的方法。

2. 发明申请

WO2004058218A2 PREFILMING ATOMIZER 审中-公开
标题翻译：预制件
公开(公告)号：WO2004058218A2
公开(公告)日：2004-07-15
申请号：PCT/US2003/040166
申请日：2003-12-16
申请人： NEKTAR THERAPEUTICS , SNYDER, Herman, E. , NASIATKA, James , VARGA, Christopher, M.
发明人： SNYDER, Herman, E. , NASIATKA, James , VARGA, Christopher, M.
IPC分类号： A61K9/00
CPC分类号： B05B7/0441 , A61K9/0073 , A61K9/1682 , B05B7/0416 , B05B7/0433 , B05B7/0466 , B05B7/062 , B05B7/065 , B05B7/067 , B05B7/0807 , F23D2900/11101
摘要： A method of forming droplets comprises flowing a liquid through a channel; spreading the liquid into a thin film in the channel; and impinging the thin film with a flowing gas to atomize the liquid into droplets. The droplets may then be dried to produce dried particles, such as particles comprising a pharmaceutical active agent. The droplets formed by the disclosed process have improved size and/or size distribution characteristics.
摘要翻译：形成液滴的方法包括使液体流过通道; 将液体分散在通道中的薄膜中; 并用流动的气体冲击薄膜以将液体雾化成液滴。然后可以将液滴干燥以产生干燥的颗粒，例如包含药物活性剂的颗粒。由所公开的方法形成的液滴具有改进的尺寸和/或尺寸分布特性。

3. 发明申请

WO2012154883A2 VENTILATION DEVICES AND RELATED PARTS AND METHODS 审中-公开
标题翻译：通风装置及相关部件及方法
公开(公告)号：WO2012154883A2
公开(公告)日：2012-11-15
申请号：PCT/US2012/037163
申请日：2012-05-09
申请人： CAREFUSION 207, INC. , BIRCH, Stephen J. , DILLINGHAM, Thomas , DUGAN, Greg, J. , MANSOUR, Khalid, Said , PIERRO, Brian, W. , PORTEOUS, Eric , VARGA, Christopher, M.
发明人： BIRCH, Stephen J. , DILLINGHAM, Thomas , DUGAN, Greg, J. , MANSOUR, Khalid, Said , PIERRO, Brian, W. , PORTEOUS, Eric , VARGA, Christopher, M.
IPC分类号： A61M16/06 , A61M16/20 , A61M16/08 , A61B5/097 , A61B5/087
CPC分类号： A61M16/0003 , A61B5/0836 , A61B5/087 , A61B5/097 , A61B5/6803 , A61M15/08 , A61M15/085 , A61M16/0051 , A61M16/024 , A61M16/0463 , A61M16/0611 , A61M16/0627 , A61M16/0683 , A61M16/0825 , A61M16/0833 , A61M16/085 , A61M16/0883 , A61M16/10 , A61M16/105 , A61M16/1055 , A61M16/107 , A61M16/14 , A61M16/20 , A61M2016/0027 , A61M2016/0039 , A61M2202/0208 , A61M2202/062 , A61M2205/0205 , A61M2205/0238 , A61M2205/18 , A61M2205/584 , A61M2205/6054 , A61M2205/6072 , A61M2205/70 , A61M2205/75 , A61M2230/432
摘要： This writing discusses a method for adjusting a ventilation mask, a ventilation mask seal, a nasal passage opener, a carbon dioxide sampling device, configuration for use of a reusable insert, a lateral gas line, a non-invasive tube insertion region and exhaust port, a protective facial interface, and quick donning headgear.
摘要翻译：本文讨论了一种调节通气面罩的方法，通气面罩密封件，鼻通道开启器，二氧化碳取样装置，用于可重复使用的插入物的构造，侧向气体管线，非侵入性管插入区域和排气口，保护性面部界面，快速穿戴头饰。

4. 发明申请

WO2012099985A2 MAIN STREAM GAS ANALYZING DEVICE 审中-公开
标题翻译：主流气体分析装置
公开(公告)号：WO2012099985A2
公开(公告)日：2012-07-26
申请号：PCT/US2012/021759
申请日：2012-01-18
申请人： CAREFUSION 2200, INC. , VARGA, Christopher, M.
发明人： VARGA, Christopher, M.
IPC分类号： G01N21/37 , G01N33/497
CPC分类号： G01N21/3504 , G01N21/031 , G01N33/497
摘要： A main stream gas analyzing device for measuring a concentration of a trace gas present in a gas stream and a method of measuring the concentration of the trace gas is disclosed. The main stream gas analyzing device includes a measuring chamber for receiving a gas flow, an infrared reflective material provided on an inner surface of the measuring chamber, an infrared radiation source directed toward the infrared reflective material of the measuring chamber and obliquely angled relative to a longitudinal axis of the measuring chamber such that infrared radiation being emitted from the infrared radiation source is reflected off of the infrared reflective material at least once, and an infrared radiation detector obliquely angled relative to the longitudinal axis of the measuring chamber to receive the reflected infrared radiation.
摘要翻译：公开了一种用于测量气流中痕量气体浓度的主流气体分析装置和一种测量痕量气体浓度的方法。主流气体分析装置包括用于接收气流的测量室，设置在测量室的内表面上的红外反射材料，指向测量室的红外反射材料且相对于测量室的红外反射材料倾斜的红外辐射源使得从红外辐射源发射的红外辐射从红外反射材料反射至少一次，并且红外辐射检测器相对于测量室的纵向轴线倾斜地倾斜以接收反射的红外线辐射。

5. 发明申请

WO2020214490A1 GAS VALVE FOR VENTILATION, A CIRCUIT FOR A VENTILATION SYSTEM AND A METHOD FOR DETERMINING A RELEASING GAS FLOW 审中-公开
公开(公告)号：WO2020214490A1
公开(公告)日：2020-10-22
申请号：PCT/US2020/027570
申请日：2020-04-10
申请人： IMTMEDICAL AG , VARGA, Christopher, M.
发明人： VARGA, Christopher, M. , HESS, Martin Björn , VAN DER STAAY, Matthias
IPC分类号： A61M16/20 , A61M16/08 , A61M16/00 , A61M16/10
摘要： The invention discloses a gas valve (11) for ventilation, comprising a main body (12) having a first gas chamber (13), a second gas chamber (15) and at least an inlet duct (14) for supplying a gas to the first gas chamber (13). The gas valve (11) further comprises a proportional valve (24) for temporally sealing the first gas chamber (13) from the second gas chamber (15). The second gas chamber (15) comprises at least a second passage opening (22) for releasing the gas from the second gas chamber (15) and the second gas chamber (15) comprises a port (30) for connecting a pressure measurement apparatus for measuring the gas pressure in the second gas chamber (15). The invention further discloses a circuit with a ventilation limb comprising a gas valve (11) and a method for determining a releasing gas flow of a gas valve.

6. 发明申请

WO2012071427A9 HUMIDIFICATION SYSTEM 审中-公开
公开(公告)号：WO2012071427A9
公开(公告)日：2012-05-31
申请号：PCT/US2011/061873
申请日：2011-11-22
申请人： CAREFUSION 2200, INC. , DIXON, Paul, David , VARGA, Christopher, M. , KORNEFF, Neil, Alex
发明人： DIXON, Paul, David , VARGA, Christopher, M. , KORNEFF, Neil, Alex
IPC分类号： A61M16/16 , A61M16/00 , G05B13/00

7. 发明申请

WO2012047903A2 NON-INVASIVE BREATHING ASSISTANCE APPARATUS AND METHOD 审中-公开
标题翻译：非侵入式呼吸辅助装置及方法
公开(公告)号：WO2012047903A2
公开(公告)日：2012-04-12
申请号：PCT/US2011/054787
申请日：2011-10-04
申请人： CAREFUSION 207, INC. , VARGA, Christopher, M. , WISE, Geoffrey, C.
发明人： VARGA, Christopher, M. , WISE, Geoffrey, C.
IPC分类号： A61M16/00 , A61M15/08 , A61M11/02
CPC分类号： A61M16/0666 , A61M16/00 , A61M16/0057 , A61M16/0672 , A61M16/0858 , A61M2240/00
摘要： An nCPAP device for assisting patient breathing includes a generator body forming an inlet, a chamber, and first and second flow circuits. The chamber directs pressurized gas from the inlet to the flow circuits. The flow circuits each include a nozzle, a channel, and at least one port. The nozzle emits a jet stream into the channel in a direction of a patient side thereof. The port fluidly connects the channel to ambient, and promotes entrainment of ambient air with the jet stream. In some embodiments, the channel forms a ramp feature directing exhaled air toward the jet stream in an angular fashion. The generator body requires reduced driving pressures to achieve target CPAP levels and reduces total imposed WOB as compared to conventional designs.
摘要翻译：用于帮助患者呼吸的nCPAP装置包括形成入口，腔室和第一和第二流动回路的发生器主体。腔室将加压气体从入口引导到流动回路。流动回路各自包括喷嘴，通道和至少一个端口。喷嘴沿其患者侧的方向将射流发射到通道中。端口将通道流畅地连接到环境，并且促进带有喷射流的环境空气的夹带。在一些实施例中，通道形成以倾斜方式将呼出的空气朝向喷射流引导的斜坡特征。与常规设计相比，发电机体需要降低的驱动压力以实现目标CPAP水平并减少总施加的WOB。

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