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    • 2. 发明申请
    • IMMUNOSTIMULATING POLYSACCHARIDES ISOLATED FROM CURCUMA XANTHORRHIZA AND MANUFACTURING METHOD THEREOF
    • 免疫球蛋白分离多糖和其制备方法
    • WO2006135197A1
    • 2006-12-21
    • PCT/KR2006/002282
    • 2006-06-14
    • HWANG, Jae-KwanKIM, Ah-JinSOHN, Jong-HeeHAN, Kyu-LeeLEE, Sun-HeeCHOO, Jeong-Han
    • HWANG, Jae-KwanKIM, Ah-JinSOHN, Jong-HeeHAN, Kyu-LeeLEE, Sun-HeeCHOO, Jeong-Han
    • C08B37/00
    • C08B37/006C12P19/04
    • The present invention provides a method for manufacturing polysaccharides isolated from Curcuma xanthorrhiza , including steps of: (S1) preparing a powder of Curcuma xanthorrhiza Roxb .; (S2) extracting the powder with an organic solvent, and then filtering or centrifuging to obtain a residue; (S3) extracting the residue to prepare a solution containing polysaccharides; (S4) removing starch by adding starch-hydrolyzing enzyme to the polysaccharides-containing solution; (S5) precipitating the polysaccharides after the step (S4); and (S6) purifying the polysaccharides after the step (S5), polysaccharides obtained according to the manufacturing method, and a pharmaceutical composition in eluding the polysaccharides as effective component. The polysaccharides according to the present invention may be very effectively used in drugs and functional foods for stimulating macrophage activity, preventing and treating immunological diseases including cancer, and enhancing immunity after the treatment of the immunological diseases.
    • 本发明提供了从姜黄分离的多糖的制造方法,包括以下步骤:(S1)制备姜黄黄酮粉末; (S2)用有机溶剂萃取粉末,然后过滤或离心得到残留物; (S3)提取残渣以制备含有多糖的溶液; (S4)通过向含多糖溶液中加入淀粉水解酶除去淀粉; (S5)在步骤(S4)后沉淀多糖; 和(S6)步骤(S5)后的多糖的纯化,根据制造方法得到的多糖,以及除了多糖作为有效成分的药物组合物。 本发明的多糖可以非常有效地用于药物和功能性食品中,用于刺激巨噬细胞活性,预防和治疗免疫疾病,包括癌症,以及增强免疫疾病治疗后的免疫力。