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1. 发明申请

WO0206535A2 METHOD FOR BREEDING DISEASE RESISTANT DOMESTICATED FOWL 审中-公开
标题翻译：育种抗病家禽的方法
公开(公告)号：WO0206535A2
公开(公告)日：2002-01-24
申请号：PCT/US0122519
申请日：2001-07-19
申请人： HOPE CITY
发明人： MILLER MARCIA M , AFANASSIEFF MARIELLE , BRILES W ELWOOD
IPC分类号： A01K67/027 , C12Q1/68
CPC分类号： C12Q1/6881 , A01K67/027 , C12Q1/686 , C12Q1/6876 , C12Q1/6883 , C12Q2600/124 , C12Q2600/156 , C12Q2600/172
摘要： Disease resistance in domesticated fowl has been associated with the B and Rfp-Y systems of major histocompatability genes. A method for breeding domesticated fowl to produce disease resistant offspring involves selecting at least one parent that has a B genotype, an Rfp-Y genotype or both that is characteristic of disease resistance and mating that parent with a second parent to produce a disease resistant offspring.
摘要翻译：驯养家禽的抗病性与主要组织相容性基因的B和Rfp-Y系统相关。用于育种家禽以产生抗病性后代的方法包括选择至少一种具有B基因型，Rfp-Y基因型或两者的亲本，其具有抗病性特征，并将该亲本与第二亲本交配以产生抗病性后代。

2. 发明申请

WO0194615A3 METHOD FOR BREEDING AND GENOTYPING CHICKENS AND PROBES THEREFOR 审中-公开
标题翻译：用于育种和基因组的方法和方法
公开(公告)号：WO0194615A3
公开(公告)日：2003-10-02
申请号：PCT/US0117684
申请日：2001-06-01
申请人： HOPE CITY
发明人： MILLER MARCIA M , GOTO RONALD M
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , C12Q2600/124 , C12Q2600/156 , C12Q2600/172
摘要： Disease resistance in domesticated fowl, and in particular, chickens, has been associated with certain alleles of the Rfp-Y and B systems of major histocompatibility genes in the birds. This invention provides a method of genotyping chickens which is useful for different breeds of chickens raised for meat and eggs. Methods for selecting disease-resistant chickens and for breeding disease-resistant chickens are also provided. The invention provides oligonucleotide probes for use in the methods. The haplotyping method can be used to select for breeding chickens having a reduced incidence and/or severity of disease, for example, Marek's disease and greater vigor and fecundity.
摘要翻译：家禽，特别是鸡中的抗病性与鸟类中主要组织相容性基因的Rfp-Y和B系统的某些等位基因相关。本发明提供了一种用于基因分型鸡的方法，该方法对于用于肉和鸡蛋的不同品种的鸡是有用的。还提供了选择抗病鸡和育种抗病鸡的方法。本发明提供了用于该方法的寡核苷酸探针。单倍型方法可用于选择具有降低的疾病的发病率和/或严重程度的繁殖鸡，例如马立克氏病和更大的活力和繁殖力。

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