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1. 发明申请

WO2004049949A1 FULL FIELD MAMMOGRAPHY WITH TISSUE EXPOSURE CONTROL, TOMOSYNTHESIS, AND DYNAMIC FIELD OF VIEW PROCESSING 审中-公开
标题翻译：具有组织接触控制，动力学和动态视野处理领域的全场动画
公开(公告)号：WO2004049949A1
公开(公告)日：2004-06-17
申请号：PCT/US2003/037763
申请日：2003-11-26
申请人： HOLOGIC, INC. , JING, Zhenxue , HITZKE, Georgia , KENNEDY, Donald , SMITH, Andrew , STEIN, Jay, A.
发明人： JING, Zhenxue , HITZKE, Georgia , KENNEDY, Donald , SMITH, Andrew , STEIN, Jay, A.
IPC分类号： A61B6/04
CPC分类号： A61B6/502 , A61B6/025 , A61B6/06 , A61B6/4035 , A61B6/4291 , A61B6/482
摘要： A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast (20 and 22) and of breast density (26, 28, 30 and 32) to automatically derive one or more technic factors (24). The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid (12d) on the x-ray source (12a) and also maintains the field of view of the x-ray receptor (12c). Finally, the system finds an outline that forms a reduced field of view (48) that still encompasses the breast in the image (46), and uses for further processing, transmission or archival storage the data within said reduced field of view (48).
摘要翻译：依赖于压缩和固定的乳房（20和22）的厚度估计和乳房密度（26,28,30和32）的自动导出一个或多个技术因素（24）的组织暴露控制的乳房摄影系统。该系统进一步使用将防散射栅格（12d）的焦点保持在x射线源（12a）上并且还保持x射线受体（12c）的视野的断层合成装置。最后，系统找到形成仍然包含图像（46）中的乳房的缩小视场（48）的轮廓，并且用于进一步处理，传输或存档在所述缩小视场（48）内的数据，。

2. 发明申请

WO2012122399A1 SYSTEM AND METHOD FOR DUAL ENERGY AND/OR CONTRAST ENHANCED BREAST IMAGING FOR SCREENING, DIAGNOSIS AND BIOPSY 审中-公开
标题翻译：用于筛选，诊断和生物学的双能量和/或对比增强乳腺成像的系统和方法
公开(公告)号：WO2012122399A1
公开(公告)日：2012-09-13
申请号：PCT/US2012/028334
申请日：2012-03-08
申请人： HOLOGIC, INC. , SMITH, Andrew, Paul , STEIN, Jay , JING, Zhenxue , REN, Baorui , NIKLASON, Loren , RUTH, Christopher , SHAW, Ian
发明人： SMITH, Andrew, Paul , STEIN, Jay , JING, Zhenxue , REN, Baorui , NIKLASON, Loren , RUTH, Christopher , SHAW, Ian
IPC分类号： G06K9/00
CPC分类号： A61B6/025 , A61B6/12 , A61B6/4035 , A61B6/4417 , A61B6/463 , A61B6/466 , A61B6/481 , A61B6/482 , A61B6/502 , A61B6/5235 , A61B10/04 , A61M5/007 , F04C2270/041
摘要： Systems and methods for x-ray imaging a patient's breast in combinations of dual-energy, single-energy, mammography and tomosynthesis modes that facilitate screening for and diagnosis of breast abnormalities, particularly breast abnormalities characterized by abnormal vascularity.
摘要翻译：双能量，单能量，乳房X射线摄影和断层合成模式的X射线成像X射线成像的系统和方法，有助于筛查和诊断乳房异常，特别是以血管异常为特征的乳房异常。

3. 发明申请

WO2010101930A1 MAMMOGRAPHY/TOMOSYNTHESIS SYSTEMS AND METHODS AUTOMATICALLY DERIVING BREAST CHARACTERISTICS FROM BREAST X-RAY IMAGES AND AUTOMATICALLY ADJUSTING IMAGE PROCESSING PARAMETERS ACCORDINGLY 审中-公开
标题翻译： MAMMOGRAPHY / TOMOSYNTHESIS系统和方法自动从BREAST X射线图像中获得乳腺特征，并自动调整图像处理参数
公开(公告)号：WO2010101930A1
公开(公告)日：2010-09-10
申请号：PCT/US2010/025937
申请日：2010-03-02
申请人： HOLOGIC, INC. , SMITH, Andrew, Paul , CHEN, Biao , JING, Zhenxue
发明人： SMITH, Andrew, Paul , CHEN, Biao , JING, Zhenxue
IPC分类号： G06T5/00
CPC分类号： A61B6/545 , A61B6/482 , A61B6/502 , G06T5/00 , G06T2207/30068
摘要： Methods and systems that automatically identify breast characteristics such as x-ray density and breast texture from initial x-ray images of the breast and automatically adjust process parameter setting of image processing algorithms that operate on the initial images to derive processing images suitable for display or further processing.
摘要翻译：从乳房的初始x射线图像自动识别乳房特征如x射线密度和乳房纹理的方法和系统，并自动调整对初始图像进行操作的图像处理算法的过程参数设置，以得到适合于显示的处理图像或进一步处理。

4. 发明申请

WO2012048000A2 UPRIGHT X-RAY BREAST IMAGING WITH A CT MODE, MULTIPLE TOMOSYNTHESIS MODES, AND A MAMMOGRAPHY MODE 审中-公开
标题翻译：具有CT模式，多种TOMOSYNTHESIS模式和MAMMOGRAPHY模式的直立X射线乳腺成像
公开(公告)号：WO2012048000A2
公开(公告)日：2012-04-12
申请号：PCT/US2011/054926
申请日：2011-10-05
申请人： HOLOGIC, INC. , SMITH, Andrew, Paul , STEIN, Jay , DEFREITAS, Kenneth , SHAW, Ian , JING, Zhenxue , NIKLASON, Loren , REN, Baorui , RUTH, Christopher
发明人： SMITH, Andrew, Paul , STEIN, Jay , DEFREITAS, Kenneth , SHAW, Ian , JING, Zhenxue , NIKLASON, Loren , REN, Baorui , RUTH, Christopher
IPC分类号： A61B6/03
CPC分类号： A61B6/502 , A61B6/025 , A61B6/027 , A61B6/032 , A61B6/04 , A61B6/0414 , A61B6/405 , A61B6/4441 , A61B6/4447 , A61B6/461 , A61B6/463 , A61B6/466 , A61B6/482 , A61B6/5235
摘要： A multi-mode system and method for imaging a patient's breast with x- rays in one or more of a CT mode, a narrow-angle tomosynthesis mode, a wide angle tomosynthesis mode, and a mammography mode, using essentially the same equipment, on one or more compressions or immobilizations of the breast.
摘要翻译：一种多模式系统和方法，用于使用基本上相同的设备，以CT模式，窄角度断层合成模式，广角断层合成模式和乳房摄影模式中的一种或多种中的X射线成像患者的乳房乳房的一个或多个按压或固定。

5. 发明申请

WO2010120658A1 INTEGRATED BREAST X-RAY AND MOLECULAR IMAGING SYSTEM AND METHOD 审中-公开
标题翻译：综合乳腺X射线和分子成像系统及方法
公开(公告)号：WO2010120658A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030667
申请日：2010-04-12
申请人： HOLOGIC, INC. , STEIN, Jay , REN, Baorui , SMITH, Andrew , BROOKS, Ken , JING, Zhenxue , SHAW, Ian , DEFREITAS, Ken
发明人： STEIN, Jay , REN, Baorui , SMITH, Andrew , BROOKS, Ken , JING, Zhenxue , SHAW, Ian , DEFREITAS, Ken
IPC分类号： A61B6/00 , A61B6/02 , A61B6/04
CPC分类号： A61B6/0414 , A61B6/025 , A61B6/037 , A61B6/06 , A61B6/4021 , A61B6/4291 , A61B6/4411 , A61B6/4441 , A61B6/502 , A61B6/5235
摘要： An integrated tomosynthesis/ molecular breast imaging device having improved sensitivity includes tomosynthesis imaging components and molecular breast imaging components. The imaging components may be used individually or in combination to provide a system with improved sensitivity and specificity. Molecular imaging components may be smoothly advanced or withdrawn depending upon the desired imaging mode. The system supports both PET and SPECT imaging and enables SPECT collimation to be modified in accordance with image capture requirements.
摘要翻译：具有改进的灵敏度的综合的断层合成/分子乳房成像装置包括断层成像成像组件和分子乳腺成像组件。成像组件可以单独使用或组合使用以提供具有改善的灵敏度和特异性的系统。根据期望的成像模式，分子成像组件可以顺利地前进或撤回。该系统支持PET和SPECT成像，并且可以根据图像捕获要求修改SPECT准直。

6. 发明申请

WO2010120636A1 SYSTEM AND METHOD FOR MOLECULAR BREAST IMAGING WITH BIOPSY CAPABILITY AND IMPROVED TISSUE COVERAGE 审中-公开
标题翻译：具有生物能力和改善组织覆盖的分子乳腺成像系统和方法
公开(公告)号：WO2010120636A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030473
申请日：2010-04-09
申请人： HOLOGIC, INC. , REN, Baorui , SMITH, Andrew, P. , BROOKS, Ken , JING, Zhenxue , STEIN, Jay
发明人： REN, Baorui , SMITH, Andrew, P. , BROOKS, Ken , JING, Zhenxue , STEIN, Jay
IPC分类号： A61B6/00 , G01T1/164 , G01T1/166 , A61B17/34 , G21K1/02
CPC分类号： A61B6/4411 , A61B6/037 , A61B6/4021 , A61B6/4258 , A61B6/4291 , A61B6/502 , A61B6/5235 , G01T1/1611 , G01T1/1642 , G21K1/025
摘要： An dual head molecular based imaging system includes at least one gamma camera having slanted collimators. The use of one or more slant collimators can greatly improve viewing coverage of a dual-head gamma camera breast imaging system, providing improved three-dimensional localization and biopsy capability as well as improved coverage of axilla and chest wall tissue. The dual-head gamma camera breast imaging capability may be provided in a dedicated system, or alternatively as part of a fused x-ray, molecular based imaging system.
摘要翻译：双头分子基成像系统包括具有倾斜准直仪的至少一个伽马相机。使用一个或多个倾斜准直器可以大大改善双头伽马相机乳房成像系统的观看覆盖范围，提供改进的三维定位和活检能力以及改善腋窝和胸壁组织的覆盖。双头伽马相机乳房成像能力可以在专用系统中提供，或者作为融合的x射线，基于分子的成像系统的一部分提供。

7. 发明申请

WO2010060007A1 METHOD AND SYSTEM FOR CONTROLLING X-RAY FOCAL SPOT CHARACTERISTICS FOR TOMOSYNTHESIS AND MAMMOGRAPHY IMAGING 审中-公开
标题翻译：用于控制X射线焦点特征的方法和系统，用于骨骼形成和乳腺成像
公开(公告)号：WO2010060007A1
公开(公告)日：2010-05-27
申请号：PCT/US2009/065451
申请日：2009-11-23
申请人： HOLOGIC INC. , REN, Baorui , STEIN, Jay , JING, Zhenxue , SMITH, Andrew
发明人： REN, Baorui , STEIN, Jay , JING, Zhenxue , SMITH, Andrew
IPC分类号： A61B6/03 , H05G1/52 , H01J35/24
CPC分类号： A61B6/4021 , A61B6/025 , A61B6/032 , A61B6/502 , H01J35/14 , H05G1/52
摘要： An x-ray tube is described that includes components for increasing x-ray image clarity in the presence of a moving x-ray source by modifying focal spot characteristics, including focal spot size and focal spot position, tn a first arrangement a static focal spot is moved in a direction contrary to the movement of the x-ray source so that an effective focal spot position is essentially fixed in space relative to one of the imaged object and/or detector during a tomosynthesis exposure. In a second arrangement, the size of the static focal spot is increased, and the resulting increase in tube current reduces the exposure time and concomitant blur effect. The methods may be used alone or in combination; for example an x-ray tube with a larger, moveable static focal spot will result in a system that fully utilizes the x-ray tube generator, provides a high quality image with reduced blur and, due to the decrease in exposure time, may scan the patient more quickly.
摘要翻译：描述了一种X射线管，其包括用于通过改变焦点特性（包括焦斑尺寸和焦点位置）来改变在存在移动的X射线源的X射线图像清晰度的组件，在第一布置静态焦点在与x射线源的运动相反的方向上移动，使得在断层融合曝光期间，有效焦点位置相对于成像对象和/或检测器之一基本上固定在空间中。在第二种布置中，静态焦点的尺寸增加，并且由此导致的管电流的增加降低了曝光时间并伴随着模糊效果。这些方法可以单独使用或组合使用; 例如具有较大可移动静电焦点的X射线管将导致完全利用x射线管发生器的系统，提供具有减少的模糊的高质量图像，并且由于曝光时间的减少可能扫描病人更快

8. 发明申请

WO2010028208A1 INTEGRATED MULTI-MODE MAMMOGRAPHY/TOMOSYNTHESIS X-RAY SYSTEM AND METHOD 审中-公开
标题翻译：综合多模式人机界面/ TOMOSYNTHESIS X射线系统与方法
公开(公告)号：WO2010028208A1
公开(公告)日：2010-03-11
申请号：PCT/US2009/055981
申请日：2009-09-04
申请人： HOLOGIC, INC. , REN, Baorui , SMITH, Andrew , JING, Zhenxue , STEIN, Jay
发明人： REN, Baorui , SMITH, Andrew , JING, Zhenxue , STEIN, Jay
IPC分类号： A61B6/00 , A61B6/10 , A61B6/02
CPC分类号： A61B6/502 , A61B6/025 , A61B6/0414 , A61B6/107 , A61B6/4291 , A61B6/4417 , A61B6/4441 , A61B6/482 , A61B6/488 , A61B6/5235 , A61B6/545
摘要： A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes, and in a combination mode, at least one imaging procedure is executed differently in at least two imaging modes.
摘要翻译：提供了一种用于多模式乳房x射线成像的系统，其包括用于压缩和固定用于X射线成像的乳房的压缩臂组件，X射线管组件和x射线图像接收器。该系统被配置用于多个成像协议和模式，并且在组合模式中，在至少两个成像模式中不同地执行至少一个成像过程。

9. 发明申请

WO2022204024A1 PATIENT SHIELD FOR AN X-RAY IMAGING SYSTEM AND METHODS OF THE SAME 审中-公开
公开(公告)号：WO2022204024A1
公开(公告)日：2022-09-29
申请号：PCT/US2022/021139
申请日：2022-03-21
申请人： HOLOGIC, INC.
发明人： DEFREITAS, Kenneth, F. , REN, Baorui , BURCHFIELD, Brent, L. , JING, Zhenxue
IPC分类号： A61B6/03 , A61B6/04 , A61B6/10
摘要： An imaging system (100) includes a gantry (126) and a compression arm assembly (104). The compression arm assembly (104) including a support arm (122) supporting a compression paddle (108), a platform (106), and an x-ray receptor (114). An x-ray tube head (124) includes an x-ray source (120). A patient shield system (138) is disposed between the compression paddle (108) and the x-ray source (120). The patient shield system (138) includes an arm (142), a carrier (144), a shield (140), and at least one leg (416, 450, 475, 502) supporting the shield (140) on the carrier (144). A 0° tube head angle is defined as the x-ray source (120) being orthogonal to the support platform (106), and the at least one leg (416, 450, 475, 502) is positioned on the support arm (122) such that the at least one leg (416, 450, 475, 502) is between a ±8° and ±15° tube head angle.

10. 发明申请

WO2021022206A1 SYSTEMS AND METHODS FOR AUTOMATING CLINICAL WORKFLOW DECISIONS AND GENERATING A PRIORITY READ INDICATOR 审中-公开
公开(公告)号：WO2021022206A1
公开(公告)日：2021-02-04
申请号：PCT/US2020/044593
申请日：2020-07-31
申请人： HOLOGIC, INC.
发明人： CHEN, Biao , JING, Zhenxue , KSHIRSAGAR, Ashwini , GKANATSIOS, Nikolaos , CHUI, Haili
IPC分类号： G16H20/40 , G16H10/60 , G16H30/20 , G16H50/20 , G16H50/30 , G16H70/20
摘要： Examples of the present disclosure describe systems and methods for automating clinical workflow decisions. In aspects, patient data may be collected from multiple data sources, such as patient records, imaging data, etc. The patient data may be processed using an artificial intelligence (AI) component. The output of the AI component may be used by healthcare professionals to inform healthcare decisions for patients. The output of the AI component and additional information relating to the healthcare decisions and healthcare paths may be provided as input to a decision analysis component. The decision analysis component may process the input and output an automated healthcare recommendation that may be used to further inform the healthcare decisions of the healthcare professionals. In some aspects, the output of the decision analysis component may be used to determine a priority or timeline for performing one or more actions relating to patient healthcare.

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