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1. 发明申请

WO2004059002A3 METHOD FOR DETERMINING THE HOMEOSTASIS OF HAIRY SKIN 审中-公开
标题翻译：方法用于确定体内平衡毛发的皮肤
公开(公告)号：WO2004059002A3
公开(公告)日：2005-06-30
申请号：PCT/EP0314070
申请日：2003-12-11
申请人： HENKEL KGAA , PETERSOHN DIRK , SCHLOTMANN KORDULA , GASSENMEIER THOMAS , HOLTKOETTER OLAF , CONRADT MARCUS , HOFMANN KAY
发明人： PETERSOHN DIRK , SCHLOTMANN KORDULA , GASSENMEIER THOMAS , HOLTKOETTER OLAF , CONRADT MARCUS , HOFMANN KAY
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/148 , C12Q2600/158
摘要： The invention relates to a method for determining the homeostasis of hairy skin in vitro, to test kits and biochips for determining markers of hairy skin, in addition to the use of proteins, mRNA molecules or fragments of proteins or mRNA molecules as markers of hairy skin. The invention also relates to a test method for detecting the effectiveness of cosmetic or pharmaceutical active substances for treating hairy skin in addition to a screening method for identifying cosmetic or pharmaceutical active substances for treating hairy skin and to a method for producing a cosmetic or pharmaceutical preparation for treating hairy skin.
摘要翻译：本发明涉及一种用于确定在体外，检测试剂盒和生物芯片稳态多毛皮肤标记物多毛皮肤的测定和使用蛋白质，mRNA分子或蛋白质或mRNA分子作为标记物多毛皮肤的片段; 此外，用于展示治疗头皮，以及用于鉴定化妆品或药剂用于治疗头皮的筛选方法，以及用于制备用于治疗头皮的化妆品或药物组合物的方法的化妆品或药物制剂的效力的测试方法。

2. 发明申请

WO2004059001A3 METHOD FOR DETERMINING MARKERS OF HUMAN FACIAL SKIN 审中-公开
标题翻译：用于确定标志物人的脸部皮肤
公开(公告)号：WO2004059001A3
公开(公告)日：2005-03-03
申请号：PCT/EP0314068
申请日：2003-12-11
申请人： HENKEL KGAA , PETERSOHN DIRK , SCHLOTMANN KORDULA , GASSENMEIER THOMAS , HOLTKOETTER OLAF , CONRADT MARCUS , HOFMANN KAY
发明人： PETERSOHN DIRK , SCHLOTMANN KORDULA , GASSENMEIER THOMAS , HOLTKOETTER OLAF , CONRADT MARCUS , HOFMANN KAY
IPC分类号： A61K8/02 , A61Q19/00 , C12Q1/68 , G01N33/68
CPC分类号： C12Q1/6876 , C12Q2600/148 , C12Q2600/158 , G01N33/6881
摘要： The invention relates to a method for determining the homeostasis of human facial skin in vitro, to test kits and biochips for determining markers of human facial skin, in addition to the use of proteins, mRNA molecules or fragments of proteins or mRNA molecules as markers of human facial skin. The invention also relates to a test method for detecting the effectiveness of cosmetic or pharmaceutical active substances for treating human facial skin in addition to a screening method for identifying cosmetic or pharmaceutical active substances for treating human facial skin and to a method for producing a cosmetic or pharmaceutical preparation for treating human facial skin.
摘要翻译：本发明涉及一种用于确定在体外，检测试剂盒和生物芯片人的面部皮肤的体内平衡为人类面部皮肤的并涉及使用蛋白质，mRNA分子或蛋白质或mRNA分子的片段是人的面部皮肤的标记物标记的确定; 此外，用于展示人的面部皮肤的治疗，以及用于识别化妆品或药剂的对人的面部皮肤的治疗和用于人的面部皮肤的治疗的化妆品或药物制剂的制备方法的筛选方法的化妆品或药物制剂的效力的测试方法。

3. 发明申请

WO02053774A3 METHOD FOR DETERMINING HOMEOSTASIS OF THE SKIN 审中-公开
标题翻译：方法用于确定稳态SKIN
公开(公告)号：WO02053774A3
公开(公告)日：2003-07-17
申请号：PCT/EP0115179
申请日：2001-12-20
申请人： HENKEL KGAA , PETERSOHN DIRK , CONRADT MARCUS , HOFMANN KAY
发明人： PETERSOHN DIRK , CONRADT MARCUS , HOFMANN KAY
IPC分类号： C12Q1/68 , G01N33/50
CPC分类号： C12Q1/6883 , C12Q1/6837 , C12Q2600/158
摘要： The invention relates to a method for determining homeostasis of the skin in the skin of humans or animals in vitro. The invention also relates to test kits and biochips for determining homeostasis of the skin, in addition to the use of proteins, mRNA molecules or fragments of proteins or mRNA molecules as markers for homeostasis of the skin. The invention further relates to a test method for determining the efficacy of cosmetic or pharmaceutical active substances in order to maintain or promote homeostasis of the skin or in order to treat pathological conditions of the skin, as well as a screening method for the identification of cosmetic or pharmaceutical active substances for the maintenance or promotion of homeostasis of the skin or in order to treat pathological conditions of the skin and to a method for producing a cosmetic or pharmaceutical preparation in order to maintain or promote homeostasis of the skin or in order to treat pathological conditions of the skin.
摘要翻译：本发明涉及一种用于确定在人类中或在体外动物，测试成套工具和生物芯片皮肤的体内平衡，用于确定皮肤的内环境稳定和使用蛋白质，mRNA分子或蛋白的片段或mRNA分子作为标记物皮肤的动态平衡; 或进一步的测试方法用于证明化妆品或药物剂的有效性，以维持或促进皮肤的动态平衡或用于治疗皮肤的病理状况，以及用于鉴定化妆品或药剂，以维持或促进皮肤的体内平衡的筛选方法用于皮肤的病理状况的治疗和用于制备化妆品或药物组合物以维持或促进皮肤的或用于皮肤的病理状况的治疗的体内平衡的方法。

4. 发明申请

WO02053773A3 METHOD FOR DETERMINING SKIN STRESS OR SKIN AGEING IN VITRO 审中-公开
标题翻译：程序来确定皮肤应力或体外时效
公开(公告)号：WO02053773A3
公开(公告)日：2003-08-28
申请号：PCT/EP0115178
申请日：2001-12-20
申请人： HENKEL KGAA , PETERSOHN DIRK , CONRADT MARCUS , HOFMANN KAY
发明人： PETERSOHN DIRK , CONRADT MARCUS , HOFMANN KAY
IPC分类号： A61P17/00 , C12Q1/68 , G01N33/68 , A61K7/00 , A61K31/7088 , A61K38/00 , G01N33/50
CPC分类号： C12Q1/6883 , C12Q1/6837 , C12Q2600/158 , G01N33/6803 , G01N33/6881 , G01N2800/20
摘要： The invention relates to a method for determining skin stress and/or skin ageing in humans or animals in vitro, test kits and biochips for determining skin stress and/or skin ageing, and the use of proteins, mRNA molecules or fragments of proteins or mRNA molecules as skin stress and/or ageing markers. The invention also relates to a test method for demonstrating the effectiveness of cosmetic or pharmaceutical active ingredients against skin stress and/or skin ageing, a screening method for identifying cosmetic or pharmaceutical active ingredients against skin stress and/or skin ageing, and a method for producing a cosmetic and/or pharmaceutical preparation against skin stress and/or skin ageing. The invention further relates to a cosmetic or pharmaceutical preparation against skin stress and/or skin ageing.
摘要翻译：本发明涉及一种方法，用于确定皮肤的应力和/或皮肤中体外人类或动物，检测试剂盒和生物芯片老化，用于确定皮肤的应力和/或皮肤老化并涉及使用蛋白质，mRNA分子或蛋白质的片段或 mRNA分子作为应力和/或皮肤标记物的老化; 另外，测试方法用于证明的针对皮肤的应力和/或老化的化妆品或药物活性物质的有效性，以及用于针对皮肤的应力和/或皮肤的化妆品或药物活性物质老化鉴定的筛选方法和用于制备化妆品或药物制剂的对皮肤应力的方法和/ 或老化。此外，对皮肤的压力和/或老化的化妆品或药物制剂。

5. 发明申请

WO0155198A9 DERMO- AND GASTRO-SPECIFIC SPHINGOLIPID ACTIVATOR 审中-公开
标题翻译：皮肤和具体鞘脂AKTIVATOR胃
公开(公告)号：WO0155198A9
公开(公告)日：2003-08-14
申请号：PCT/EP0100877
申请日：2001-01-26
申请人： MEMOREC MEDICAL MOLECULAR RES , HOFMANN KAY , CONRADT MARCUS
发明人： HOFMANN KAY , CONRADT MARCUS
IPC分类号： A61K38/00 , A61P3/00 , C07K14/475 , C12N15/12 , C07K14/47 , A01K67/027 , A61K7/00 , A61K38/17 , C12N5/10 , C12N15/11 , C12Q1/68
CPC分类号： C07K14/475 , A01K2217/05 , A61K38/00
摘要： The invention relates to dermo- and gastro-specific pro-saposin eSAP.
摘要翻译：本发明公开了一种皮肤和具体胃亲鞘脂ESAP。

6. 发明申请

WO0155198A2 DERMO- AND GASTRO-SPECIFIC SPHINGOLIPID ACTIVATOR 审中-公开
标题翻译：皮肤和具体鞘脂AKTIVATOR胃
公开(公告)号：WO0155198A2
公开(公告)日：2001-08-02
申请号：PCT/EP0100877
申请日：2001-01-26
申请人： MEMOREC MEDICAL MOLECULAR RES , HOFMANN KAY , CONRADT MARCUS
发明人： HOFMANN KAY , CONRADT MARCUS
IPC分类号： A61K38/00 , A61P3/00 , C07K14/475 , C12N15/12 , C07K14/47 , A01K67/027 , A61K7/00 , A61K38/17 , C12N5/10 , C12N15/11 , C12Q1/68
CPC分类号： C07K14/475 , A01K2217/05 , A61K38/00
摘要： The invention relates to dermo- and gastro-specific pro-saposin eSAP.
摘要翻译：本发明公开了一种皮肤和具体胃亲鞘脂ESAP。

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