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1. 发明申请

WO2019152363A1 AXIAL BLOOD PUMP WITH IMPELLER RINSE OPERATION 审中-公开
公开(公告)号：WO2019152363A1
公开(公告)日：2019-08-08
申请号：PCT/US2019/015561
申请日：2019-01-29
申请人： HEARTWARE, INC.
发明人： CASAS, Fernando , REYES, Carlos , WOLMAN, Justin , JOHNSON, Thomas R.
IPC分类号： A61M1/10 , A61M1/12
CPC分类号： A61M1/1029 , A61M1/1012 , A61M1/1086 , A61M1/122 , A61M2205/50
摘要： A method of controlling a blood pump including executing a control command to temporarily displace an impeller of the blood pump within a pump housing from a first axial position relative to the pump housing to a second axial position a distance away from the first axial position using a vector control method, and causing the impeller to move from the second axial position to a third axial position, the third axial position including a positive and a negative displacement of the impeller relative to the first axial position.

2. 发明申请

WO2019067230A1 INSTRUMENTED DRIVELINE USING A FLEXIBLE ARTIFICIAL SKIN SENSORY ARRAY 审中-公开
公开(公告)号：WO2019067230A1
公开(公告)日：2019-04-04
申请号：PCT/US2018/051013
申请日：2018-09-14
申请人： HEARTWARE, INC.
发明人： CASAS, Fernando
IPC分类号： A61M1/10 , A61M1/12
摘要： A driveline for an implantable blood pump including a percutaneous connector including an outer tube, the outer tube defining an exterior surface and having a proximal portion and a distal portion opposite the proximal portion, the proximal portion being couplable to the implantable blood pump disposed within a body of a patient and the distal portion being couplable to a controller outside of the body of the patient and at least one electronic instrument coupled to the outer tube and fluidically sealed from the exterior surface of the outer tube.

3. 发明申请

WO2018026655A2 HEART RATE DETERMINATION BASED ON VAD CURRENT WAVEFORM 审中-公开
标题翻译：基于VAD电流波形的心率测定
公开(公告)号：WO2018026655A2
公开(公告)日：2018-02-08
申请号：PCT/US2017/044459
申请日：2017-07-28
申请人： HEARTWARE, INC.
发明人： REYES, Carlos , CASAS, Fernando , WOLMAN, Justin
IPC分类号： A61M1/10
摘要： The present disclosure provides for methods and systems for determining heart rate of a patient. Based on motor current signals of a ventricular assist device (VAD), each of first, second and third events in the measured current signal may be detected, the first event being indicative of a rise or fall in the current signal, the second event being indicative of a rise or fall in the current signal in the opposite direction as the first event, and the third event being indicative of a rise or fall in the current signal in the same direction as the first event. A timer counter may be initiated upon detection of the first event, and an elapsed time may be measured upon detection of the third event. Heart rate may be determined based on the elapsed time of the timer counter.
摘要翻译：本公开提供了用于确定患者的心率的方法和系统。基于心室辅助装置（VAD）的电机电流信号，可以检测测量的电流信号中的第一事件，第二事件和第三事件中的每一个事件，第一事件指示电流信号的上升或下降，第二事件是指示电流信号在与第一事件相反的方向上的上升或下降，并且第三事件指示电流信号在与第一事件相同的方向上的上升或下降。定时器计数器可以在检测到第一事件时启动，并且可以在检测到第三事件时测量流逝的时间。心率可以基于计时器计数器的经过时间来确定。

4. 发明申请

WO2021141703A1 PULSATILE BLOOD PUMP VIA CONTRACTION WITH SMART MATERIAL 审中-公开
公开(公告)号：WO2021141703A1
公开(公告)日：2021-07-15
申请号：PCT/US2020/063569
申请日：2020-12-07
申请人： HEARTWARE, INC.
发明人： SCHAFIR, David A. , CASAS, Fernando
IPC分类号： A61M60/178 , A61M60/232 , A61M60/569 , A61M60/81 , A61M60/833 , A61M60/857 , A61M60/892 , A61M2205/0294 , A61M2205/04 , A61M60/148 , A61M60/205
摘要： An inflow cannula for an implantable blood pump, the inflow cannula defining an inlet at a proximal end, an opposite distal end, and a lumen therebetween, the inflow cannula being configured to constrict the lumen

5. 发明申请

WO2021076267A1 PULSATILE BLOOD PUMP WITH ACTIVE ELEMENT AND THROMBUS RINSE 审中-公开
公开(公告)号：WO2021076267A1
公开(公告)日：2021-04-22
申请号：PCT/US2020/051386
申请日：2020-09-18
申请人： HEARTWARE, INC.
发明人： CASAS, Fernando , TASKIN, Mustafa E. , SCHAFIR, David A.
IPC分类号： A61M1/10 , A61M1/12
摘要： An implantable blood pump includes a housing defining an inlet and an outlet and a flow path therethrough. A rotor is disposed within the housing. A stator is disposed within the housing, the stator being configured to rotate the rotor when a current is applied to the stator. A volute is disposed distal to the rotor proximate the outlet, the volute including a tongue composed of a piezoelectric material.

6. 发明申请

WO2019194976A1 MULTI-INPUT SPEED RESPONSE ALGORITHM FOR A BLOOD PUMP 审中-公开
公开(公告)号：WO2019194976A1
公开(公告)日：2019-10-10
申请号：PCT/US2019/023181
申请日：2019-03-20
申请人： HEARTWARE, INC.
发明人： REYES, Carlos , CHORPENNING, Katherine , FERREIRA, Antonio Luiz Silva , VASUDEVAN JALAJA, Neethu Lekshmi , WOLMAN, Justin , CASAS, Fernando
IPC分类号： A61M1/10 , A61M1/12
摘要： A method of responding to an adverse event associated with an implantable blood pump including detecting the adverse event, reducing a pump speed of the blood pump relative to a set pump speed in response to the detected adverse event, and determining whether at least one of a group consisting of the adverse event and a second adverse event is present following the reducing of the pump speed of the blood pump. If the at least one of the group consisting of the adverse event and a second adverse event is not present, the method includes increasing the pump speed to the set pump speed and if the at least one of the group consisting of the adverse event and a second adverse event is present while increasing the pump speed to the set pump speed, the method includes reducing the pump speed to a maximum safe operating speed.

7. 发明申请

WO2019125999A1 HEART RATE MEASUREMENT USING BLOOD PUMP IMPELLER LOCATION 审中-公开
公开(公告)号：WO2019125999A1
公开(公告)日：2019-06-27
申请号：PCT/US2018/065936
申请日：2018-12-17
申请人： HEARTWARE, INC.
发明人： WOLMAN, Justin , CASAS, Fernando , REYES, Carlos
IPC分类号： A61M1/12 , A61M1/10
CPC分类号： A61M1/12 , A61M1/1012 , A61M1/1031 , A61M1/1086 , A61M1/122 , A61M2205/3334
摘要： A method of determining a heart rate of a patient having an implanted blood pump including applying a voltage to a plurality of coils of a stator of the blood pump to produce an electromagnetic force to rotate a rotor in communication with the plurality of coils; displaying a waveform associated with a back electromotive force in the plurality of coils of the blood pump, the waveform being proportional to an axial position of the rotor relative to the stator; determining a time interval between a first alteration in the waveform relative to a baseline and a second alteration in the waveform relative to the baseline; and determining the heart rate of the patient based on the time interval.

8. 发明申请

WO2019067233A1 DRIVE LINE INFECTION PREVENTION USING A FLEXIBLE ARTIFICIAL SKIN ULTRA VIOLET (UV) LIGHT EMITTER 审中-公开
公开(公告)号：WO2019067233A1
公开(公告)日：2019-04-04
申请号：PCT/US2018/051034
申请日：2018-09-14
申请人： HEARTWARE, INC.
发明人： CASAS, Fernando
IPC分类号： A61N5/06 , A61M39/16 , A61L2/10 , A61M39/02
摘要： A driveline for an implantable blood pump including a percutaneous outer tube configured to connect with the blood pump when the blood pump is implanted within a body of a patient and an external controller outside of the body of the patient and at least one ultra-violet light emitter coupled to the outer tube.

9. 发明申请

WO2018026655A3 HEART RATE DETERMINATION BASED ON VAD CURRENT WAVEFORM 审中-公开
公开(公告)号：WO2018026655A3
公开(公告)日：2018-02-08
申请号：PCT/US2017/044459
申请日：2017-07-28
申请人： HEARTWARE, INC.
发明人： REYES, Carlos , CASAS, Fernando , WOLMAN, Justin
IPC分类号： A61M1/10
摘要： The present disclosure provides for methods and systems for determining heart rate of a patient. Based on motor current signals of a ventricular assist device (VAD), each of first, second and third events in the measured current signal may be detected, the first event being indicative of a rise or fall in the current signal, the second event being indicative of a rise or fall in the current signal in the opposite direction as the first event, and the third event being indicative of a rise or fall in the current signal in the same direction as the first event. A timer counter may be initiated upon detection of the first event, and an elapsed time may be measured upon detection of the third event. Heart rate may be determined based on the elapsed time of the timer counter.

10. 发明申请

WO2022186950A1 BLOOD PUMP IMPELLER 审中-公开
公开(公告)号：WO2022186950A1
公开(公告)日：2022-09-09
申请号：PCT/US2022/015400
申请日：2022-02-07
申请人： HEARTWARE, INC.
发明人： CASAS, Fernando , TASKIN, Mustafa Ertan
IPC分类号： A61M60/122 , A61M60/802 , A61M60/804 , A61M60/808
摘要： An implantable blood pump including an impeller, at least a portion of the impeller being composed of a metal alloy that is a solid at normal body temperature and is configured to phase change to a liquid between a predetermined temperature above normal body temperature and about 40 degrees Celsius.

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