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    • 10. 发明申请
    • ASSAY APPARATUS COMPRISING AN IMPLANTED LIGHT SOURCE
    • 包含有光源的测试装置
    • WO2005120335A3
    • 2006-03-02
    • PCT/IL2005000593
    • 2005-06-06
    • GLUCON INCBITTON GABRIELPESACH BENNYNAGAR RON
    • BITTON GABRIELPESACH BENNYNAGAR RON
    • A61B5/00A61B5/07
    • A61B5/0028A61B5/0031A61B5/0095A61B5/076A61B5/14532A61B5/6862A61B5/6876A61B2560/0219
    • Apparatus for assaying an analyte in a patient's blood comprising: at least one light source (22) implanted in the patient's body controllable to illuminate blood in a blood vessel (40) in the body with light at at least one wavelength that is absorbed and/or scattered by the analyte and as a result generates photoacoustic waves in the blood; at least one acoustic transducer (32) coupled to the body that receives acoustic energy from the photoacoustic waves and generates signals responsive thereto; and a processor (34) that receives the signals and processes them to determine a concentration of the analyte in the illuminated tissue region. Another embodiment of the apparatus comprises a light source and an optical detector mounted to a stent and optically coupled by a light pipe wherein light undergoes attenuated total reflection along the light pipe responsive to concentration of the analyte in the blood.
    • 用于测定患者血液中的分析物的装置,包括:植入患者体内的至少一个光源(22),其可控制以用至少一种波长的光照射身体中的血液(40),所述至少一种波长被吸收和/ 或被分析物散射,从而在血液中产生光声波; 耦合到所述主体的至少一个声换能器(32),其从所述光声波接收声能并响应于此产生信号; 以及接收信号并处理它们以确定被照射的组织区域中的分析物的浓度的处理器(34)。 该装置的另一实施例包括光源和光学检测器,其安装到支架上并通过光管光学耦合,其中光响应于血液中分析物的浓度而沿着光管经历衰减的全反射。