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    • 2. 发明申请
    • FUNCTIONAL POLYARYLETHERS
    • 功能性聚合物
    • WO2008073536A1
    • 2008-06-19
    • PCT/US2007/076218
    • 2007-08-17
    • GENERAL ELECTRIC COMPANYZHANG, YanshiSTEIGER, DanielSURIANO, Joseph, AnthonyYEAGER, Gary, William
    • ZHANG, YanshiSTEIGER, DanielSURIANO, Joseph, AnthonyYEAGER, Gary, William
    • A61M1/16B01D71/52B01D71/68C08G65/48C08G75/23
    • B01D71/52B01D69/08B01D2325/34C08G65/40C08G65/48C08G75/23
    • Membranes comprising functional polyarylether having structural units of formula (Il) are useful for hemodialysis and hemofiltration, wherein X is selected from Br, NR 4 R 5 , OOCR 6 , OR 7 , NR 4 COR 5 , NR 4 CONR 5 R 6 , NR 4 COOR 5 R 6 and combinations thereof; R 1 , R 2 and R 3 are independently at each occurrence H, X, halo, cyano, nitro, a C 1 -C 12 aliphatic radical, a C 3 -C 12 cycloaliphatic radical, a C 3 -C 12 aromatic radical or a combination thereof; R 4 and R 5 are independently H, a C 1-10 aliphatic radical, a C 3 -C 12 cycloaliphatic radical, a C 3 -C 12 aromatic radical, or a combination thereof; R 6 is H, a C 2-10 aliphatic radical, a C 3 -C 12 cycloaliphatic radical, a C 3 -C 12 aromatic radical or a combination thereof; R 7 is OCH 2 CH 2 (OCH 2 CH 2 ) n OH or OOCCH 2 (OCH 2 CH 2 ) n CH 3 ; Q is a direct bond, O, S, CH 2 , alkenyl, alkynyl, a C 1 -C 12 aliphatic radical, a C 3 -C 12 cycloaliphatic radical, a C 3 -C 12 aromatic radical or a combination thereof; Z is a direct bond, O, S, CH 2 , SO, SO 2 , CO, phenylphospinyl oxide, alkenyl, alkynyl, a C 1 -C 12 aliphatic radical, a C 3 -C 12 cycloaliphatic radical, a C 3 -C 12 aromatic radical or a combination thereof; a, b, and c are independently 1 or 2; and m, n and p are independently 0 or 1.
    • 包含具有式(II)结构单元的官能聚芳醚的膜可用于血液透析和血液滤过,其中X选自Br,NR4R5,O0CR6 或,NR 4,OR 4,OR 4,OR 5, 其中6个,6个,5个,6个和其组合; R 1,R 2和R 3在每次出现时独立地为H,X,卤素,氰基,硝基,C 1 C 1 -C 12脂族基团,C 3 -C 12脂环族基团,C 3〜 -C 12芳族基团或其组合; R 4和R 5独立地是H,C 1-10烷基脂族基,C 3 -C 12脂环族基团,C 3 -C 12 - 芳族基团或其组合; R 6是H,C 2-10脂族基团,C 3 -C 12 - 脂环族基团, C 3 -C 12芳族基团或其组合; R 2是OCH 2 CH 2(OCH 2 CH 2 CH 2) ; Q是直接键合,O,S,CH 2,烯基,炔基,C 1 -C 12脂族基,C 1 -C 12烷基, C 3 -C 12脂环族基团,C 3 -C 12芳族基团或其组合; Z是直接键,O,S,CH 2,SO,SO 2,CO,苯基氧化烯,烯基,炔基,C 1 C 12-12脂族基团,C 3 -C 12脂环族基团,C 3 -C 3脂肪族基团, 芳基或其组合; a,b和c独立地为1或2; m,n和p独立地为0或1。