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1. 发明申请

WO2007012977A2 STEROID KIT AND FOAMABLE COMPOSITION AND USES THEREOF 审中-公开
标题翻译： STEROID包装和可泡沫组合物及其用途
公开(公告)号：WO2007012977A2
公开(公告)日：2007-02-01
申请号：PCT/IB2006002832
申请日：2006-04-18
申请人： FOAMIX LTD , FREIDMAN DORON , BESONOV ALEX , TAMAKRIN DOV , EINI MEIR
发明人： FREIDMAN DORON , BESONOV ALEX , TAMAKRIN DOV , EINI MEIR
IPC分类号： A61K8/04 , A61K8/67 , A61K31/07 , A61K31/203 , A61L9/04 , A61M11/00 , A61Q19/00
CPC分类号： A61K9/122 , A61K8/046 , A61K8/671 , A61K9/0014 , A61K31/07 , A61K31/203 , A61K31/56 , A61K31/568 , A61K31/573 , A61Q19/00
摘要： A composition and therapeutic kit including an aerosol packaging assembly including: a container accommodating a pressurized product; and an outlet capable of releasing the pressurized product as a foam; wherein the pressurized product comprises a foamable composition including: i. a steroid; ii. at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, a polar solvent, an emollient and mixtures thereof, at a concentration of about 2% to about 50% by weight; iii. a surface-active agent; iv. about 0.01 % to about 5% by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent; v. water; and vi. liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition. The composition further may include a therapeutically active foam adjuvant, selected from the group consisting of a fatty alcohol, a fatty acid, a hydroxyl fatty acid; and mixtures thereof.
摘要翻译：一种组合物和治疗试剂盒，其包括气溶胶包装组件，包括：容纳加压产品的容器; 以及能够释放作为泡沫的加压产品的出口; 其中所述加压产品包括可发泡组合物，其包含：i。类固醇 II。选自浓度为约2％至约50％重量的至少一种选自疏水性有机载体，极性溶剂，润肤剂及其混合物的有机载体; III。表面活性剂; IV。约0.01重量％至约5重量％的至少一种选自生物粘附剂，胶凝剂，成膜剂和相变剂的聚合物添加剂; v。水和vi。液化或压缩气体推进剂的浓度为总组合物重量的约3％至约25％。组合物还可以包括治疗活性的泡沫佐剂，其选自脂肪醇，脂肪酸，羟基脂肪酸; 及其混合物。

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