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    • 1. 发明申请
    • AN ULTRASONIC SURGICAL INSTRUMENT FOR INTRACORPOREAL SONODYNAMIC THERAPY
    • 超声波手术治疗超声心动图
    • WO2003002189A2
    • 2003-01-09
    • PCT/US2002/020431
    • 2002-06-27
    • ETHICON ENDO-SURGERY, INC.ETHICON ENDO-SURGERY, INC.
    • MAKIN, Inder,, Raj., S.,JURGEN,, Noppe,JOHANNES, MARIA,, Marcus,
    • A61N
    • A61M37/0092A61N7/00
    • The present invention relates, in general, to ultrasonic surgical instruments and, more particularly, to an intracorporeal ultrasonic surgical instrument for sonodynamic therapy. Disclosed is an ultrasonic surgical system comprising: a generator and an instrument comprising: a housing; a transducer; a semi-permeable membrane; a pharmaceutical agent; and an agent delivery system. The transducer is adapted to convert the electrical energy of the generator into mechanical energy. The pharmaceutical agent, delivered into a chamber of the semi-permeable membrane, is driven through the semi-permeable membrane by the mechanical energy. A method in accordance with the present invention comprises the steps of: providing a surgical instrument comprising: a housing; a transducer connected to the housing; a semi-permeable membrane; a pharmaceutical agent; and an agent delivery system; inserting the surgical instrument into a patient; delivering a drug to the patient; and locally activating the drug with the surgical instrument.
    • 本发明一般涉及超声外科器械,更具体地,涉及用于声波动力学治疗的体外超声外科器械。 公开了一种超声波手术系统,包括:发生器和器械,包括:壳体; 换能器 半透膜; 药剂; 和代理分发系统。 换能器适于将发电机的电能转换为机械能。 输送到半透膜的室中的药剂通过机械能驱动通过半透膜。 根据本发明的方法包括以下步骤:提供外科器械,包括:外壳; 连接到壳体的换能器; 半透膜; 药剂; 和代理交付系统; 将外科器械插入患者体内; 向患者运送药物; 并用手术器械局部活化药物。