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    • 1. 发明申请
    • METHOD OF EVALUATING THE EFFECTS OF EXOGENOUS AND ENDOGENOUS FACTORS ON THE SKIN
    • 评估外源性和内源性因子对皮肤的影响的方法
    • WO2007067536A1
    • 2007-06-14
    • PCT/US2006/046388
    • 2006-12-05
    • ELC MANAGEMENT LLCAFRIAT, IsabelleRAFAILOVICH, MiriamGUAN, E
    • AFRIAT, IsabelleRAFAILOVICH, MiriamGUAN, E
    • G01N33/15G01N33/483
    • A61B5/445A61B5/0088A61B5/442
    • The present invention provides non-invasive, in vivo, DISC-type methods of evaluating structural changes in skin due to a variety of exogenous or endogenous factors. It is possible to develop quantitative and qualitative characterizations of skin. For example, the skin may be characterized based on its structural age rather than its chronological age. Based on the structural age and type of an individual's skin, cosmetic, dermatologic, medicinal or manipulative treatment may be customized. The method is based, in part, on quantification of discontinuities that arise in the skin during normal facial expression. The methods provide for evaluating changes in human skin response that occur over a short term (one day) or long term (one or more years). The methods provide for evaluating the skin's response to cosmetic, dermatologic or medicinal treatment or to any other factor alleged to affect the skin.
    • 本发明提供了由多种外源或内源因素评价皮肤结构变化的非侵入式体内DISC型方法。 可以开发皮肤的定量和定性表征。 例如,皮肤可以基于其结构年龄而不是其时间年龄来表征。 根据个人皮肤的结构年龄和类型,可以定制化妆品,皮肤病学,药物或操作性治疗。 该方法部分地基于在正常面部表情期间在皮肤中产生的不连续性的量化。 该方法用于评估短期(一天)或长期(一年或多年)发生的人类皮肤反应变化。 该方法用于评估皮肤对化妆品,皮肤病学或药物治疗的反应或任何其他影响皮肤的因素。