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1. 发明申请

WO0158408A3 MULTI-PURPOSE DRUG AND HEAT THERAPY TREATMENT SYSTEM 审中-公开
标题翻译：多用途药物和治疗治疗系统
公开(公告)号：WO0158408A3
公开(公告)日：2002-03-07
申请号：PCT/US0103432
申请日：2001-02-02
申请人： DVORETZKY ISRAEL , KULEZA JOHN E
发明人： DVORETZKY ISRAEL , KULEZA JOHN E
IPC分类号： A61F7/02 , A61F7/03 , A61K9/70 , A61L15/16 , A61N1/30
CPC分类号： A61F7/02 , A61F7/034 , A61F2007/0001 , A61F2007/0225 , A61F2007/0261 , A61K9/70
摘要： By providing an integrated, easily employed holding or support member (21) which is uniquely constructed for cooperating with a heat delivery patch or exothermic pad (28) for optimizing the application of heat directly to a precisely desired location, a local, easily employed, convenient, consumer oriented treatment system (20) for providing heat therapy for a wide variety of medical problems is achieved. In accordance with the present invention, a fully integrated treatment system is realized which possesses broad applicability for a wide range of medical conditions which can be treated or improved by heat penetration into the skin, subcutaneous tissues, joints, muscles, blood streams, etc. In addition, it has also been found that the delivery of drugs, penetration enhancing agents and/or cosmetics through the skin for the purpose of achieving a non-oral and/or non-parenteral, systemic, transdermal delivery is effectively enhanced by the presence of a controlled heat gradient.
摘要翻译：通过提供一种集成的，容易使用的保持或支撑构件（21），其独特地构造用于与用于优化直接施加到精确期望位置的热传递贴片或放热垫（28）配合，本地，易于使用，实现了为各种医疗问题提供热疗的便利，消费者导向的治疗系统（20）。根据本发明，实现了一种完全集成的治疗系统，其具有广泛的适用于广泛的医疗条件，其可以通过热量渗入皮肤，皮下组织，关节，肌肉，血液等而被治疗或改善。此外，还发现通过皮肤递送药物，穿透增强剂和/或化妆品以实现非口服和/或非肠胃外全身性透皮递送的目的，通过存在的受控热梯度。

2. 发明申请

WO02055023A3 THERAPEUTIC FILM FORMING COMPOSITION AND TREATMENT SYSTEM 审中-公开
标题翻译：治疗膜成型和治疗系统
公开(公告)号：WO02055023A3
公开(公告)日：2002-11-07
申请号：PCT/US0200282
申请日：2002-01-07
申请人： DVORETZKY ISRAEL , KULEZA JOHN E
发明人： DVORETZKY ISRAEL , KULEZA JOHN E
IPC分类号： A61K47/18 , A61K8/42 , A61K8/81 , A61K9/08 , A61K9/70 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/38 , A61L15/44 , A61L26/00 , A61M35/00 , A61M37/00 , A61Q3/02 , A61Q19/00 , A61F13/00
CPC分类号： A61Q3/02 , A61F7/02 , A61K8/42 , A61K8/8152 , A61K9/7015 , A61Q19/00
摘要： By providing a film forming composition incorporationg one or more therapeutic substances for application to nails and/or skin surfaces which can be employed independently or, if desired, in combination with an easily employed holding or support member for delivering heat directly to the application site an easily employed, convenient, consumer-oriented treatment system is achieved for treating nails and/or skin surfaces for a wide variety of medical problems. The treatment system of the present invention possesses broad applicability for a wide range of medical conditions, including the mumerous diseases, disorders, and medical problems, all of which are capable of being treated using the present invention. In particular, diseases, disorders, and medical conditionss which include, but are not limited to, psoriasis, skin cancers, warts, leishmaniasis, mycobacteria, and granuloma annulare can be specifically treated or improved due to the efficacy of the present invention and, when employed, the efficacy of heat penetration in treating these disorders.
摘要翻译：通过提供一种成膜组合物并入一种或多种用于指甲和/或皮肤表面的治疗物质，其可以独立使用，或者如果需要，与容易使用的用于将热量直接传递到施用部位的保持或支撑构件组合，易于使用，方便，消费者导向的治疗系统可用于治疗各种医疗问题的指甲和/或皮肤表面。本发明的治疗系统对广泛的医疗条件具有广泛的适用性，包括可以使用本发明进行治疗的多种疾病，病症和医学问题。特别地，由于本发明的功效，可以具体地治疗或改善包括但不限于牛皮癣，皮肤癌，疣，利什曼病，分枝杆菌和肉芽肿环的疾病，病症和医学病症，并且当使用，热渗透在治疗这些疾病中的功效。

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