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2. 发明申请

WO1998005645A1 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY 审中-公开
标题翻译：具有杀真菌活性的4-取代的喹啉衍生物
公开(公告)号：WO1998005645A1
公开(公告)日：1998-02-12
申请号：PCT/US1997013090
申请日：1997-07-31
申请人： DOW AGROSCIENCES LLC
发明人： DOW AGROSCIENCES LLC , DAEUBLE, John , DAVIS, L., Navell , HELLWIG, Karin , KIRBY, Neil , PARKER, Marshall, H. , PIECZKO, Mary , THOMASON, Lori, K.
IPC分类号： C07D215/18
CPC分类号： C07D401/12 , A01N43/42 , A01N43/54 , C07D215/18
摘要： This invention provides compounds of formula (1) wherein X is CR , where R is H, Cl or CH3; Y is CR where R is H, Cl, or Br; Z is O, S, SO, SO2, NR , where R is H, C1-C4 alkyl, C1-C4 acyl, CR R , where R and R are independently H, C1-C4 alkyl, C1-C4 alkenyl, C2-C4 alkynyl, C1-C4 acyl, CN, or OH, or R and R together combine to form a carbocyclic ring containing four to six carbon atoms; V is CR R where R and R are independently H, C1-C4 alkyl, C1-C4 alkenyl, C2-C4 alkynyl, C1-C4 acyl, CN, optionally substituted phenoxy, halo C1-C4 alkyl, or OH, or R and R together combine to form a carbocyclic ring containing four to six carbon atoms; A is (a) a C1-C18 saturated or unsaturated straight or branched hydrocarbon chain, optionally including a hetero atom selected from O, S, SO, or SO2, and optionally substituted with halo, halo C1-C4 alkoxy, OH, or C1-C4 acyl; (b) C3-C8 cycloalkyl or cycloalkenyl; (c) a possibly substituted phenyl group; (d) a furyl group of formula (3); (e) a thienyl group; (f) a group of formula (5) or (5a); (g) a group selected from pyridyl or substituted pyridyl; (h) a group selected from pyrimidinyl or substituted pyrimidinyl; or (i) a group selected from 1-naphthyl, substituted 1-naphthyl, 4-pyrazolyl, 3-methyl-4-pyrazolyl, 1,3-benzodioxolyl, tricyclo[3.3.1.1(3,7)]dec-2-yl,1-(3-chlorophenyl)-1H-tetrazol-5-yl, pyridyl, substituted pyridyl, or an acid addition salt of a compound of formula (1), or an N-oxide of a compound of formula (1) where Y is CH. The compounds of formula (1) are plant fungicides.
摘要翻译：本发明提供式（1）化合物，其中X为CR 5，其中R 5为H，Cl或CH 3; Y是CR 5，其中R 5是H，Cl或Br; Z是O，S，SO，SO 2，NR 6，其中R 6是H，C 1 -C 4烷基，C 1 -C 4酰基，CR 7 R 8，其中R 7和R 7， 8>独立地是H，C 1 -C 4烷基，C 1 -C 4烯基，C 2 -C 4炔基，C 1 -C 4酰基，CN或OH，或R 7和R 8一起组合形成含有四个至6个碳原子; V是CR 7 R 8，其中R 7和R 8独立地是H，C 1 -C 4烷基，C 1 -C 4烯基，C 2 -C 4炔基，C 1 -C 4酰基，CN，任选取代的苯氧基，卤代C 1 -C 4烷基或OH，或R 7和R 8一起结合形成含有4-6个碳原子的碳环; A是（a）C1-C18饱和或不饱和的直链或支链烃链，任选地包括选自O，S，SO或SO 2的杂原子，并且任选地被卤素，卤代C 1 -C 4烷氧基，OH或C 1 -C4酰基; （b）C 3 -C 8环烷基或环烯基; （c）可能取代的苯基; （d）式（3）的呋喃基; （e）噻吩基; （f）式（5）或（5a）的基团; （g）选自吡啶基或取代的吡啶基的基团; （h）选自嘧啶基或取代的嘧啶基的基团; 或（i）选自1-萘基，取代的1-萘基，4-吡唑基，3-甲基-4-吡唑基，1,3-苯并二恶唑基，三环[3.3.1.1（3,7） 1-（3-氯苯基）-1H-四唑-5-基，吡啶基，取代的吡啶基或式（1）化合物的酸加成盐或式（1）化合物的N-氧化物，其中Y是CH。式（1）的化合物是植物杀真菌剂。

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