专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1997037613A1 TISSUE GRAFT CONSTRUCT FOR REPLACEMENT OF CARTILAGINOUS STRUCTURES 审中-公开
标题翻译：组织结构替代纤维结构的组织结构
公开(公告)号：WO1997037613A1
公开(公告)日：1997-10-16
申请号：PCT/US1997004527
申请日：1997-04-04
申请人： DEPUY ORTHOPAEDICS, INC. , PLOUHAR, Pamela, L. , DUNN, Michael, D. , LOWER, Jerry, L. , MAY, Thomas, C.
发明人： DEPUY ORTHOPAEDICS, INC.
IPC分类号： A61F02/02
CPC分类号： A61F2/3872 , A61B17/0482 , A61B17/282 , A61B2017/00969 , A61B2017/320052 , A61F2/30756 , A61F2/3094 , A61F2/40 , A61F2/4261 , A61F2/442 , A61F2002/30461 , A61F2002/30563 , A61F2002/30971 , A61F2220/0075 , A61F2240/001 , Y10S623/908
摘要： A method of forming a reconstructive structure for cartilaginous elements, and the product produced by that method is disclosed. A length of small intestine submucosa tissue (10) is wrapped around a mandril (20) having legs (22 and 24) connected a bight (26) and diverging from that point. The diverging angle of the legs (22 and 24) of the mandril is selected to compensate for various lengths of the edges (12 and 14) and to produce flat or planar layers. The multilayered composite produced is used in the repair or replacement of cartilaginous tissues.
摘要翻译：公开了一种形成软骨元件的重建结构的方法，以及通过该方法制造的产品。一段长度的小肠粘膜下层组织（10）缠绕在具有与弯曲部分（26）连接的腿部（22和24）并从该点分叉的心轴（20）周围。选择心轴的腿部（22和24）的发散角度以补偿边缘（12和14）的各种长度并且产生平坦或平坦的层。所生产的多层复合材料用于软骨组织的修复或替代。

2. 发明申请

WO1997031966A1 POLY(ESTER-ANHYDRIDES) AND INTERMEDIATES THEREFOR 审中-公开
标题翻译：多糖（ESTER-ANHYDRIDES）及其中间体
公开(公告)号：WO1997031966A1
公开(公告)日：1997-09-04
申请号：PCT/US1997002702
申请日：1997-02-21
申请人： DEPUY ORTHOPAEDICS, INC.
发明人： DEPUY ORTHOPAEDICS, INC. , STOREY, Robson, F. , DENG, Z., David , PETERSON, Dale, R. , GLANCY, Todd, P.
IPC分类号： C08G63/692
CPC分类号： C08G63/692 , C08G63/08 , C08G67/04
摘要： Biodegradable poly(ester-anhydrides) designed to display two-stage degradation profiles are described. The presence of the anhydride linkages allows a relatively rapid decrease in molecular weight, the extend of which is governed by the concentration of the anhydride linkages along the chain, followed by possible dissolution and a slower degradation of the remaining oligomers, the rate of which is governed by the composition of the polyester prepolymers. Methods for the preparation of the poly(ester-anhydrides) and their polyester precursors are also described.
摘要翻译：描述了设计用于显示两阶段降解曲线的可生物降解的聚（酯 - 酸酐）。酸酐键的存在允许分子量的相对快速降低，其延伸由沿着链的酸酐键的浓度决定，然后可能的溶解和其余的低聚物的速率降低，其速率是由聚酯预聚物的组成决定。还描述了制备聚（酯 - 酸酐）及其聚酯前体的方法。

3. 发明申请

WO1997038633A1 POLY(AMINO ACID) ADHESIVE TISSUE GRAFTS 审中-公开
标题翻译：聚氨酯（AMINO ACID）胶粘组织
公开(公告)号：WO1997038633A1
公开(公告)日：1997-10-23
申请号：PCT/US1997006521
申请日：1997-04-16
申请人： DEPUY ORTHOPAEDICS, INC.
发明人： DEPUY ORTHOPAEDICS, INC. , PETERSON, Dale, R. , STUPP, Samuel, I.
IPC分类号： A61B17/08
CPC分类号： C09J189/00 , A61L24/043 , A61L24/106 , C08L89/00
摘要： A composition and method for repairing damaged connective tissue is provided. The composition comprises pseudo-poly(amino acids) and/or classic poly(amino acids) that exhibit adhesiveness for connective tissues. The composition is formed into an adhesive tissue repair implant and pressed against the damaged tissue to adhere the adhesive composition to the tissue.
摘要翻译：提供了修复损伤的结缔组织的组合物和方法。该组合物包含对结缔组织显示粘附性的假聚（氨基酸）和/或经典聚（氨基酸）。将组合物形成为粘合剂组织修复植入物并压靠损伤的组织以将粘合剂组合物粘附到组织上。

4. 发明申请

WO1997038975A1 POLYESTER IONOMERS FOR IMPLANT FABRICATION 审中-公开
标题翻译：用于植物生产的聚酯离子
公开(公告)号：WO1997038975A1
公开(公告)日：1997-10-23
申请号：PCT/US1997006524
申请日：1997-04-16
申请人： DEPUY ORTHOPAEDICS, INC.
发明人： DEPUY ORTHOPAEDICS, INC. , STOREY, Robson, F. , DENG, Z., David , GLANCY, Todd, P. , PETERSON, Dale, R.
IPC分类号： C07D213/22
CPC分类号： C08G63/16 , A61L27/18 , A61L31/06 , C08G63/06 , A61L31/148 , C08L67/04 , C08L67/02 , A61L27/58
摘要： Carboxy-terminated polyester ionomers useful for bioresorbable implant construction are described. They comprise biocompatible salts or partial salts of mono- or bis-carboxy-terminated polyesters.
摘要翻译：描述了可用于生物可吸收植入物结构的羧基封端的聚酯离聚物。它们包括单羧基或双羧基封端的聚酯的生物相容性盐或部分盐。

5. 发明申请

WO1997038676A1 BIOERODABLE POLYMERIC ADHESIVES FOR TISSUE REPAIR 审中-公开
标题翻译：生物可溶性聚合物粘合剂用于组织修复
公开(公告)号：WO1997038676A1
公开(公告)日：1997-10-23
申请号：PCT/US1997006520
申请日：1997-04-16
申请人： DEPUY ORTHOPAEDICS, INC.
发明人： DEPUY ORTHOPAEDICS, INC. , PETERSON, Dale, R. , DENG, Z., David , GLANCY, Todd, P.
IPC分类号： A61K09/10
CPC分类号： A61L27/18 , A61K9/204 , A61L24/0073 , A61L24/0084 , A61L24/046 , A61L27/04 , A61L27/46 , C08L67/04 , Y10S528/931
摘要： Improved matrices for tissue repair comprising a biocompatible, bioerodable polymer which has a water solubility of about 0.01 to about 500 mg/mL at about 25 DEG C and adhesive strength of about 600 to about 150,000 Pa; and pressure sensitive adhesives for tissue repair which have adhesive strength of about 600 to about 150,000 Pa. The matrix or adhesive can further comprise a filler or a bioactive agent, or both. The matrices and adhesives are tissue-adherent and dough-like so they can be molded to fit a repair site. When used for bone/implant fixation, or as a filler for bone or cartilage repair, gradual short-term bioerosion of the adhesive matrix allows it to be replaced with developing bone or cartilage tissue. When used for release of a bioactive agent, the agent can be mixed into the adhesive matrix well before the implantation procedure. After implantation, the bioactive agent is gradually released as the adhesive matrix biodegrades.
摘要翻译：用于组织修复的改进的基质包括生物相容的可生物侵蚀的聚合物，其在约25℃下的水溶解度为约0.01至约500mg / mL，粘合强度为约600至约150,000Pa; 以及粘合强度为约600至约150,000Pa的用于组织修复的压敏粘合剂。基质或粘合剂还可包含填料或生物活性剂，或两者。基质和粘合剂是组织粘附和面团状的，因此它们可以被模塑以适合修复部位。当用于骨/植入物固定时，或作为骨或软骨修复的填料时，粘合剂基质的逐渐短期生物侵蚀允许其用显影的骨或软骨组织代替。当用于释放生物活性剂时，可以在植入程序之前将试剂混合到粘合剂基质中。植入后，随着粘合剂基质的生物降解，生物活性剂逐渐释放。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式