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1. 发明申请

WO2008157344A1 RESTRAINT SYSTEM FOR A TRANSPORTATION VEHICLE 审中-公开
标题翻译：运输车辆限制系统
公开(公告)号：WO2008157344A1
公开(公告)日：2008-12-24
申请号：PCT/US2008/066903
申请日：2008-06-13
申请人： DAVIS, Phillip, J. , HOOD, Brian
发明人： DAVIS, Phillip, J. , HOOD, Brian
IPC分类号： A47C1/08
CPC分类号： B60R22/02 , B60R2022/027
摘要： A restraint system for a transportation vehicle may comprise a restraint member movably mounted to the vehicle. The restraint member may have a first leg and a second leg that travel together along opposite sides of a seat carried by the vehicle as the restraint member moves relative to the vehicle. A restraint harness may include a retractor that may be mounted to one of the first and second legs, and a lap web having one end mounted within the first retractor and an opposite end mounted to the other of the first and second legs. The lap web may be configured to restrain an occupant of the seat when the restraint member is moved to an occupant restraint position. At least one lock may be mounted to the vehicle and configured to secure the restraint member to the vehicle when the restraint member is in the occupant restraint position.
摘要翻译：用于运输车辆的约束系统可以包括可移动地安装到车辆的限制构件。约束构件可具有当约束构件相对于车辆移动时由车辆所承载的座椅的相对侧一起行进的第一腿部和第二腿部。约束束带可以包括可以安装到第一和第二腿部中的一个的牵开器，以及搭接卷边纸，其一端安装在第一牵开器内，相对端安装到第一和第二腿部中的另一个。膝盖腹板可以构造成当约束构件移动到乘员约束位置时限制座椅的乘员。至少一个锁可以安装到车辆并且被构造成当约束构件处于乘员约束位置时将约束构件固定到车辆。

2. 发明申请

WO2011159835A1 ANTIBODIES TO ENDOPLASMIN AND THEIR USE 审中-公开
标题翻译：内分泌抗体及其使用
公开(公告)号：WO2011159835A1
公开(公告)日：2011-12-22
申请号：PCT/US2011/040580
申请日：2011-06-15
申请人： UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION , FERRONE, Soldano , WANG, Xinhui , CONRADS, Thomas, P. , FAVOINO, Elvira , HOOD, Brian
发明人： FERRONE, Soldano , WANG, Xinhui , CONRADS, Thomas, P. , FAVOINO, Elvira , HOOD, Brian
IPC分类号： C07K16/30 , C12N15/13 , G01N33/574 , A61K39/395 , C12N15/63
CPC分类号： C07K16/18 , A61K39/00 , A61K47/6843 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3053 , C07K16/3069 , C07K16/3092 , C07K2317/21 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/624 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C12N5/10 , C12N15/09 , C12N15/62 , C12N15/8258 , C12N15/86 , C12N2800/00 , C12N2810/859 , G01N33/574 , G01N33/577 , G01N2333/47 , G01N2333/4727 , G01N2800/7028
摘要： Isolated monoclonal antibodies are disclosed herein that specifically bind endoplasmin. In some embodiments these antibodies are fully human. Recombinant nucleic acids encoding these antibodies, expression vectors including these nucleic acids, and host cells transformed with these expression vectors are also disclosed herein. In several embodiments the disclosed antibodies are of use for detecting and/or treating tumors that express endoplasmin, such as melanoma, breast cancer, head and neck squamous cell carcinoma, renal cancer, lung cancer, glioma, bladder cancer, ovarian cancer or pancreatic cancer. In one example, the tumor is a melanoma.
摘要翻译：本文公开了特异性结合内质网的分离的单克隆抗体。在一些实施方案中，这些抗体是完全人的。编码这些抗体的重组核酸，包括这些核酸的表达载体以及用这些表达载体转化的宿主细胞也在本文中公开。在几个实施方案中，所公开的抗体可用于检测和/或治疗表达内质网例如黑素瘤，乳腺癌，头颈鳞状细胞癌，肾癌，肺癌，神经胶质瘤，膀胱癌，卵巢癌或胰腺癌的肿瘤。在一个实例中，肿瘤是黑素瘤。

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