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1. 发明申请

WO2018098204A1 6-MEMBERED URACIL ISOSTERES 审中-公开
公开(公告)号：WO2018098204A1
公开(公告)日：2018-05-31
申请号：PCT/US2017/062902
申请日：2017-11-21
申请人： CV6 THERAPEUTICS (NI) LIMITED , SPYVEE, Mark , LEWIS, Michael
发明人： SPYVEE, Mark , LEWIS, Michael
IPC分类号： C07D211/88 , C07D239/54 , C07D401/06
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.

2. 发明申请

WO2006072083A1 LIQUID LAUNDRY DETERGENT CONTAINING FABRIC CONDITIONERS 审中-公开
标题翻译：液体洗涤剂含有织物调理剂
公开(公告)号：WO2006072083A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/047627
申请日：2005-12-21
申请人： THE DIAL CORPORATION , LIN, Bin , LEWIS, Michael , BASTIGKEIT, Thorsten
发明人： LIN, Bin , LEWIS, Michael , BASTIGKEIT, Thorsten
IPC分类号： C11D1/29 , C11D1/72 , C11D1/62 , C11D1/86
CPC分类号： C11D3/373 , C11D1/146 , C11D1/22 , C11D1/29 , C11D1/62 , C11D1/72 , C11D1/86
摘要： This invention relates to a aqueous liquid laundry composition which both cleans and conditions fabrics. The composition includes certain alcohol ethoxylates as a nonionic surfactant component, certain alkyl ether sulfates as an anionic component and a quaternary ammonium fabric softening agent. All of the foregoing are in specified proportions.
摘要翻译：本发明涉及一种水洗液体洗涤剂组合物，其均清洁和调节织物。该组合物包含某些醇乙氧基化物作为非离子表面活性剂组分，某些烷基醚硫酸盐作为阴离子组分和季铵织物软化剂。以上所有内容均为规定的比例。

3. 发明申请

WO2003046687A2 QUICK RESPONSE SYSTEM AND METHOD FOR PRODUCING VOLUMINOUS CUSTOM PLUSH PRODUCTS 审中-公开
标题翻译：快速响应系统和生产定量加料产品的方法
公开(公告)号：WO2003046687A2
公开(公告)日：2003-06-05
申请号：PCT/US2002/037232
申请日：2002-11-21
申请人： LEWIS, Michael , GERUSO, Geoff , PATTON, Virginia
发明人： LEWIS, Michael , GERUSO, Geoff , PATTON, Virginia
IPC分类号： G06F
CPC分类号： G06Q10/06 , A63H3/02
摘要： A system and method for manufacturing a product from a plurality of parts based on the result of an event includes designing each of a first group of the plurality of parts with a generic design and designing each of a second group of the plurality of parts with a cutomized design. Each of the second group of parts has at least two versions of the customized design. The first group of parts is manufactured into a partially completed product, and the second group of parts is manufactured separately. After receiving a result of the event, the manufacture of the product is completed with the partially completed product and the second group of parts designed with a version consistent with the result of the event.
摘要翻译：一种基于事件结果从多个部件制造产品的系统和方法包括用通用设计来设计多个部件的第一组中的每一个，并且用一个第二组的多个部件中的每一个设计一个精巧的设计。每个第二组零件至少有两个定制设计版本。第一组零件制造成部分完成的产品，第二组零件是单独制造的。在收到事件结果后，产品的制造完成，部分完成的产品和第二组零件的设计与事件的结果一致。

4. 发明申请

WO2011133841A3 INTRAVENOUS OMEGA-3 FATTY ACID COMPOSITIONS & METHOD OF USE 审中-公开
公开(公告)号：WO2011133841A3
公开(公告)日：2011-10-27
申请号：PCT/US2011/033542
申请日：2011-04-22
申请人： THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. , LEWIS, Michael
发明人： LEWIS, Michael
IPC分类号： A61K31/20 , A61K31/201 , A61K31/202 , A61K9/107 , A61K9/113 , A61P9/10 , A61P9/00
摘要： The invention encompasses intravenous pharmaceutical compositions containing omega-3 fatty acids and methods of treating traumatic brain injury, traumatic spinal cord injury and/or stroke using these pharmaceutical compositions.

5. 发明申请

WO2005006013A1 A METHOD AND A CENTRAL CONTROL UNIT FOR CHANNEL SWITCHING IN A PACKET-BASED COMMUNICATION NETWORK 审中-公开
标题翻译：基于分组通信网络的信道切换的方法和中央控制单元
公开(公告)号：WO2005006013A1
公开(公告)日：2005-01-20
申请号：PCT/SE2003/001894
申请日：2003-12-04
申请人： INFINEON TECHNOLOGIES AG , LEWIS, Michael , HJELM, Mikael
发明人： LEWIS, Michael , HJELM, Mikael
IPC分类号： G01S7/02
CPC分类号： G01S7/021 , G01S7/023 , H04W16/14 , H04W36/20
摘要： In a packet-based communication network a central control unit indicates its presence on the first channel by in addition to data traffic transmits regular beacons with a specified time interval, and upon detecting radar signals on a first channel the central control unit transmits a channel switch message and immediately switches to a second channel and resumes data traffic on that second channel, thereafter repeatedly transmitting a channel switch message on the first channel and a beacon on the second channel by switching back to the first channel to transmit second channel switch messages (either contained in beacons or separately) and switching back to the second channel to transmit regular beacons for each permissible beacon transmission time slot, until as many devices as possible associated with the central control unit has followed to the second channel.
摘要翻译：在基于分组的通信网络中，除了数据业务以规定的时间间隔传输规则的信标之外，中央控制单元还指示其在第一信道上的存在，并且在第一信道上检测到雷达信号时，中央控制单元发送信道切换消息并立即切换到第二信道并恢复该第二信道上的数据业务，此后在第一信道上重复发送信道切换消息和第二信道上的信标，通过切换回第一信道以发送第二信道切换消息包含在信标中或单独地），并且切换回第二信道以为每个允许的信标传输时隙传输规则信标，直到尽可能多的与中央控制单元相关联的设备已经跟随到第二信道。

6. 发明申请

WO2013103993A1 THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE 审中-公开
标题翻译：治疗化合物及其相关使用方法
公开(公告)号：WO2013103993A1
公开(公告)日：2013-07-11
申请号：PCT/US2013/020585
申请日：2013-01-07
申请人： SPROTT, Kevin , LEWIS, Michael , CHOI, Hyeongwook , FANG, Frank , SHAN, Mingde , LAZAROVA, Tsvetelina, I , LI, Lin , SIDDIQUI, M., Arshad , LAROUCHE-GAUTHIER, Robin , LEMIRE, Alexandre
发明人： SPROTT, Kevin , LEWIS, Michael , CHOI, Hyeongwook , FANG, Frank , SHAN, Mingde , LAZAROVA, Tsvetelina, I , LI, Lin , SIDDIQUI, M., Arshad , LAROUCHE-GAUTHIER, Robin , LEMIRE, Alexandre
IPC分类号： C07D493/20 , C07D519/00 , A61K31/35 , A61P35/00
CPC分类号： C07D493/20 , C07D519/00
摘要： Salinomycin analogs and pharmaceutically acceptable compositions containing salinomycin analogs. Dosage forms and kits comprising salinomycin analogs and pharmaceutically acceptable compositions containing salinomycin analogs. Methods of using salinomycin analogs, pharmaceutically acceptable compositions, dosage forms, and kits for the treatment of proliferative diseases, e.g., cancer, or microbial infections in a subject
摘要翻译：盐霉素类似物和含有盐霉素类似物的药学上可接受的组合物。包含盐霉素类似物和含有盐霉素类似物的药学上可接受的组合物的剂型和试剂盒。使用盐霉素类似物，药学上可接受的组合物，剂型和用于治疗受试者中增殖性疾病例如癌症或微生物感染的试剂盒的方法

7. 发明申请

WO2005091514A1 AC COUPLING BANDWIDTH SWITCH 审中-公开
标题翻译：交流耦合带宽开关
公开(公告)号：WO2005091514A1
公开(公告)日：2005-09-29
申请号：PCT/EP2005/002622
申请日：2005-03-11
申请人： INFINEON TECHNOLOGIES AG , LEWIS, Michael , RUDBERG, Mikael , WAGNER, Elmar
发明人： LEWIS, Michael , RUDBERG, Mikael , WAGNER, Elmar
IPC分类号： H04B1/30
CPC分类号： H04B1/30 , H03D3/008 , H04L25/06
摘要： The present invention relates to receiver equipment with AC-coupled receiver circuits and AC coupling filters. A switch (3) connected between a first stage (1) and a second stage (2) among the receiver circuits is adapted to switch from a high coupling corner frequency, for rapid settling of a signal during preparation of data reception, to a low corner frequency, for low signal distortion during data reception. The receiver circuits are adapted to use known properties in the signal to perform the switch at a time when the short term DC-components of the signal are as low as possible.
摘要翻译：本发明涉及具有AC耦合接收机电路和AC耦合滤波器的接收机设备。连接在接收器电路中的第一级（1）和第二级（2）之间的开关（3）适于从高耦合转角频率切换，以在数据接收准备期间将信号快速建立到低转角频率，用于数据接收期间的低信号失真。接收机电路适于在信号的短期DC分量尽可能低的时候使用信号中的已知特性来执行开关。

8. 发明申请

WO2005011589A2 DRUG DELIVERY METHODS AND DEVICES 审中-公开
标题翻译：药物递送方法和装置
公开(公告)号：WO2005011589A2
公开(公告)日：2005-02-10
申请号：PCT/US2004/024550
申请日：2004-07-29
申请人： EISAI CO., LTD. , LEWIS, Michael , LITTLEFIELD, Bruce, A. , CARTER, Paul, J.
发明人： LEWIS, Michael , LITTLEFIELD, Bruce, A. , CARTER, Paul, J.
IPC分类号： A61K
CPC分类号： A61K31/727 , A61F2/82 , A61F2250/0067 , A61K31/337 , A61K31/357 , A61K31/436 , A61K45/06 , A61L31/16 , A61L2300/416 , A61K2300/00
摘要： The invention provides devices and methods for delivering therapeutic agents to patients.
摘要翻译：本发明提供了将治疗剂递送给患者的装置和方法。

9. 发明申请

WO2004042991A1 A METHOD OF ERROR CONTROL CODING AND DECODING OF MESSAGES IN A PACKET-BASED DATA TRANSMISSION SYSTEM 审中-公开
标题翻译：基于分组数据传输系统的错误控制编码和消息解码的方法
公开(公告)号：WO2004042991A1
公开(公告)日：2004-05-21
申请号：PCT/SE2003/001714
申请日：2003-11-06
申请人： INFINEON TECHNOLOGIES AG , LEWIS, Michael
发明人： LEWIS, Michael
IPC分类号： H04L1/00
CPC分类号： H04L1/0061 , H03M13/03 , H04L1/0041 , H04L1/0072 , H04L69/22 , H04W84/12
摘要： In a packet-based transmission system error control coding of messages is achieved at a transmitting device between scrambling of the message frame and transmission. Initially the message frame comprising a header with frame length information, a data portion and a frame check sequence is expanded with gaps inserted to the data portion and the frame check sequence and the frame length information is updated, the frame is then scrambled and forward error correction data is generated and written into the gaps. An outer frame check sequence is generated and appended as part of the frame, after which the entire frame is transmitted. Error control decoding of the transmitted frame is achieved between reception and descrambling at a receiving device. Initially the outer frame check sequence is optionally checked and removed, an error correction algorithm based on the inserted forward error correction data is applied to the frame in response to errors, after which the frame is descrambled, the forward error correction data and the inserted gaps are removed and the frame is restored to its original state. Finally the length information of the header is updated to its original value.
摘要翻译：在基于分组的传输系统中，在发送设备之间在消息帧和传输的加扰之间实现消息的错误控制编码。首先，包括具有帧长度信息的报头，数据部分和帧校验序列的消息帧以插入数据部分的间隙和帧校验序列被更新，并且帧长度信息被更新，然后将帧加扰和前向误差生成校正数据并写入间隙。生成外帧校验序列并作为帧的一部分进行附加，之后传输整个帧。在接收设备的接收和解扰之间实现发送帧的错误控制解码。最初，可选地检查和去除外部帧检查序列，基于插入的前向纠错数据的错误校正算法响应于错误被应用于帧，之后解码帧，前向纠错数据和插入的间隙被移除并且帧恢复到其原始状态。最后，标题的长度信息被更新为其原始值。

10. 发明申请

WO2003011223A2 IMMUNOMODULATORY COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译：免疫调节化合物及其使用方法
公开(公告)号：WO2003011223A2
公开(公告)日：2003-02-13
申请号：PCT/US2002/024258
申请日：2002-07-31
申请人： EISAI CO., LTD. , HAWKINS, Lynn, D. , ISHIZAKA, Sally, T. , LEWIS, Michael , MCGUINNESS, Pamela , ROSE, Jeffrey
发明人： HAWKINS, Lynn, D. , ISHIZAKA, Sally, T. , LEWIS, Michael , MCGUINNESS, Pamela , ROSE, Jeffrey
IPC分类号： A61K
CPC分类号： C07F9/10 , A61K39/39 , A61K2039/55511 , A61K2039/55555 , C07F9/091 , C07F9/65515
摘要： The present invention is directed to novel compounds that function as immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases, to novel adjuvant formulations which include at least one of the adjuvant compounds of the invention, to novel immunostimulatory compositions which comprise an antigen and at least one of the adjuvant compounds of the invention, and to methods for the immunization of an animal by co-administration of a compound of the invention with an antigen against which the animal is to be immunized.
摘要翻译：本发明涉及当与抗原（例如细菌和病毒疾病疫苗）共施用时起免疫佐剂作用的新型化合物，涉及新型佐剂制剂，其包含至少一种佐剂化合物本发明涉及包含抗原和至少一种本发明佐剂化合物的新型免疫刺激组合物，以及通过共同给予本发明化合物与动物所针对的抗原来免疫动物的方法被免疫。

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