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1. 发明申请

WO2007054522A1 PLANTS HAVING IMPROVED GROWTH CHARACTERISTICS AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改善生长特性的植物及其制备方法
公开(公告)号：WO2007054522A1
公开(公告)日：2007-05-18
申请号：PCT/EP2006/068248
申请日：2006-11-08
申请人： CROPDESIGN N.V. , VIB VZW , UNIVERSITEIT GENT , DE MEUTTER, Jan , MIRONOV, Vladimir , REUZEAU, Christophe , INZE, Dirk , VLIEGHE, Kobe , DE VEYLDER, Lieven
发明人： DE MEUTTER, Jan , MIRONOV, Vladimir , REUZEAU, Christophe , INZE, Dirk , VLIEGHE, Kobe , DE VEYLDER, Lieven
IPC分类号： C07K14/415 , C12N15/82
CPC分类号： C12N15/8261 , C12N15/8271 , Y02A40/146
摘要： The present invention concerns a method for increasing plant yield and/or increased stress resistance by decreasing the level of activity of a DEL1 polypeptide. One such method comprises introducing into a plant a nucleic acid comprising a variant DEL1 nucleic acid. Another method comprises downregulating expression of a DEL1 gene . The invention also relates to transgenic plants having introduced therein a variant DEL1 nucleic acid thereof, which plants have increased yield and/or increased stress resistance relative to control plants. The present invention also concerns a novel DEL1 protein and its encoding sequence, and constructs useful in the methods of the invention.
摘要翻译：本发明涉及通过降低DEL1多肽的活性水平来增加植物产量和/或增加的胁迫抗性的方法。一种这样的方法包括向植物中引入包含变体DEL1核酸的核酸。另一种方法包括下调DEL1基因的表达。本发明还涉及其中引入了其变体DEL1核酸的转基因植物，该植物相对于对照植物具有增加的产量和/或增加的胁迫抗性。本发明还涉及一种新颖的DEL1蛋白及其编码序列，以及可用于本发明方法的构建体。

2. 发明申请

WO2005061702A2 PLANTS HAVING INCREASED YIELD AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有增加产量的植物及其制备方法
公开(公告)号：WO2005061702A2
公开(公告)日：2005-07-07
申请号：PCT/EP2004/053683
申请日：2004-12-22
申请人： CROPDESIGN N.V. , FRANKARD, Valerie , MIRONOV, Vladimir
发明人： FRANKARD, Valerie , MIRONOV, Vladimir
IPC分类号： C12N15/00
CPC分类号： C12N15/8261 , Y02A40/146
摘要： The invention concerns a method for increasing plant yield by introducing into a plant a cyclin A nucleic acid, preferably encoding a cyclin A protein, which cyclin A nucleic acid is operably linked to a seed-preferred promoter. By using this method, plant yield may be increased in optimal and sub-optimal growing conditions. The method results in plants having increased yield relative to corresponding wild type plants and relative to transgenic plants constitutively expressing cyclin A.
摘要翻译：本发明涉及通过将植物细胞周期蛋白A核酸（优选编码细胞周期蛋白A蛋白）引入植物来提高植物产量的方法，该细胞周期蛋白A核酸可操作地连接到种子优选的启动子。通过使用该方法，可以在优化和次优生长条件下提高植物产量。该方法导致植物相对于相应的野生型植物和相对于组成型表达细胞周期蛋白A的转基因植物具有增加的产量。

3. 发明申请

WO2003025185A1 A METHOD TO MODIFY CELL NUMBER, ARCHITECTURE AND YIELD OF PLANTS BY OVEREXPRESSING THE E2F TRANSCRIPTION FACTOR 审中-公开
标题翻译：通过过度表达E2F转录因子修饰植物细胞数，构建和产量的方法
公开(公告)号：WO2003025185A1
公开(公告)日：2003-03-27
申请号：PCT/EP2002/010236
申请日：2002-09-12
申请人： CROPDESIGN N.V. , BEECKMAN, Tom , DE VEYLDER, Lieven , INZE, Dirk , MIRONOV, Vladimir , BROEKAERT, Willem , DILLEN, Willy , FRANKARD, Valerie
发明人： BEECKMAN, Tom , DE VEYLDER, Lieven , INZE, Dirk , MIRONOV, Vladimir , BROEKAERT, Willem , DILLEN, Willy , FRANKARD, Valerie
IPC分类号： C12N15/82
CPC分类号： C12N15/8216 , C12N15/8261 , Y02A40/146
摘要： The present invention relates to a method for modifying plant growth and development processes by affecting cell cycle regulation comprising modulating expression of members of the plant E2F transcription factor family. More specific the invention relates to methods for stimulating cell division in a plant. The invention further relates to transgenic plants produced by the methods of the invention having altered plant growth and development characteristics compared to their isogenic counterparts. Preferably, the plant characteristics modified by the present invention include enlarged cotyledons, enhanced growth rate, stress resistance and seedling survival, more cells, more tillers, more panicles.
摘要翻译：本发明涉及通过影响细胞周期调节来修饰植物生长和发育过程的方法，其包括调节植物E2F转录因子家族成员的表达。更具体地，本发明涉及刺激植物细胞分裂的方法。本发明还涉及通过与其同基因对应物相比具有改变的植物生长和发育特征的本发明方法生产的转基因植物。优选地，通过本发明修饰的植物特征包括扩大的子叶，增强的生长速率，抗胁迫性和幼苗存活，更多的细胞，更多的分蘖，更多的穗。

4. 发明申请

WO2002083901A2 PLANT GROWTH REGULATING GENES, PROTEINS AND USES THEREOF 审中-公开
标题翻译：植物生长调节基因，蛋白质及其用途
公开(公告)号：WO2002083901A2
公开(公告)日：2002-10-24
申请号：PCT/EP2002/004035
申请日：2002-04-11
申请人： CROPDESIGN N.V. , SAUTER, Margret , LORBIECKE, René , MIRONOV, Vladimir , FRANKARD, Valérie , DILLEN, Willy , LEJEUNE, Pierre , BROEKAERT, Willem
发明人： SAUTER, Margret , LORBIECKE, René , MIRONOV, Vladimir , FRANKARD, Valérie , DILLEN, Willy , LEJEUNE, Pierre , BROEKAERT, Willem
IPC分类号： C12N15/29
CPC分类号： C12N15/8262 , C07K14/415 , C12N15/8237 , C12N15/8261 , Y02A40/146
摘要： Provided are methods for controlling or altering the growth characteristics of a plant or of an organ or tissue or cell of this plant. This method comprises introduction and/or expression of one or more Growth Regulating Proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Another method comprises contacting a plant or plant tissue with the purified Growth Regulated Protein or the active product derived from it. Provided are also DNA sequences encoding plant Growth Regulating Protein(s) as well as methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences, which naturally regulate the expression of the above-described DNA sequences, are described. Methods for the identification of compounds being capable of interacting with said Growth Regulating Proteins are described as well. Furthermore, transgenic plant cells, plant tissues and plants containing the above-described DNA sequences and vectors are described, as well as the use of the aforementioned DNA sequences, vectors, proteins, antibodies, regulatory sequences and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.
摘要翻译：提供了用于控制或改变植物或该植物的器官或组织或细胞的生长特性的方法。该方法包括在植物或其部分和/或编码这种蛋白质的一个或多个DNA序列中引入和/或表达一种或多种功能的生长调节蛋白。另一种方法包括使植物或植物组织与纯化的生长调节蛋白或其衍生的活性产物接触。还提供编码植物生长调节蛋白的DNA序列以及获得其的方法。此外，描述了包含所述DNA序列的载体，其中所述DNA序列可操作地连接到允许在原核和/或真核宿主细胞中表达的调节元件。此外，提供了由所述DNA序列编码的蛋白质，对所述蛋白质的抗体及其生产方法。此外，描述了调节序列，其自然调节上述DNA序列的表达。还描述了用于鉴定能够与所述生长调节蛋白相互作用的化合物的方法。此外，描述了含有上述DNA序列和载体的转基因植物细胞，植物组织和植物，以及使用上述DNA序列，载体，蛋白质，抗体，调节序列和/或化合物本发明在植物细胞和组织培养，植物育种和/或农业中。

5. 发明申请

WO2005059147A2 PLANTS HAVING MODIFIED GROWTH CHARACTERISTICS AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改良生长特性的植物及其制备方法
公开(公告)号：WO2005059147A2
公开(公告)日：2005-06-30
申请号：PCT/EP2004/053594
申请日：2004-12-17
申请人： CROPDESIGN N.V. , FRANKARD, Valerie , MIRONOV, Vladimir , SANZ MOLINERO, Ana Isabel
发明人： FRANKARD, Valerie , MIRONOV, Vladimir , SANZ MOLINERO, Ana Isabel
IPC分类号： C12N15/82
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The present invention concerns a method for modifying the growth characteristics of plants by modulating expression in a plant of a nucleic acid sequence encoding a GRUBX protein and/or modulating activity and/or levels in a plant of a GRUBX protein. The present invention furthermore provides novel GRUBX proteins and nucleic acids encoding such proteins. The invention also relates to constructs comprising GRUBX encoding nucleic acids, and transgenic plants having modified growth characteristics, which plants have modulated expression of a nucleic acid encoding a GRUBX protein.
摘要翻译：本发明涉及一种通过调节植物中编码GRUBX蛋白的核酸序列表达和/或调节GRUBX蛋白植物中的活性和/或水平来修饰植物生长特性的方法。本发明还提供了编码这种蛋白质的新型GRUBX蛋白质和核酸。本发明还涉及包含GRUBX编码核酸的构建体和具有修饰生长特性的转基因植物，该植物已经调节了编码GRUBX蛋白质的核酸的表达。

6. 发明申请

WO2003018818A2 METHOD AND MEANS FOR MODULATING PLANT CELL CYCLE PROTEINS AND THEIR USE IN PLANT CELL GROWTH CONTROL 审中-公开
标题翻译：调节植物细胞周期蛋白的方法和手段及其在植物细胞生长控制中的应用
公开(公告)号：WO2003018818A2
公开(公告)日：2003-03-06
申请号：PCT/EP2002/009504
申请日：2002-08-17
申请人： CROPDESIGN N.V. , DE VEYLDER, Lieven , INZE, Dirk , MIRONOV, Vladimir , SEGERS, Gerda
发明人： DE VEYLDER, Lieven , INZE, Dirk , MIRONOV, Vladimir , SEGERS, Gerda
IPC分类号： C12N15/82
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The present invention relates to modulation of endoreduplication in a plant or part thereof which may be achieved by modifying expression or activity of E2F or E2F in combination with DP.Modulation of endoreduplication has an advantageous influence on plant cell size and storage capacity of plant cells.
摘要翻译：本发明涉及通过改变E2F或E2F与DP组合的表达或活性来实现的植物或其部分中的内切复制的调节。内切复制的调节对植物细胞的大小和储存能力具有有利影响。

7. 发明申请

WO2008015263A2 PLANTS HAVING IMPROVED CHARACTERISTICS AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改进特性的植物及其制备方法
公开(公告)号：WO2008015263A2
公开(公告)日：2008-02-07
申请号：PCT/EP2007/058043
申请日：2007-08-02
申请人： CROPDESIGN N.V. , FRANKARD, Valerie , MIRONOV, Vladimir , REUZEAU, Christophe , SANZ MOLINERO, Ana Isabel
发明人： FRANKARD, Valerie , MIRONOV, Vladimir , REUZEAU, Christophe , SANZ MOLINERO, Ana Isabel
IPC分类号： C12N15/82 , A01H1/00 , C07K14/415
CPC分类号： C12N15/8261 , C07K14/415 , C12N9/16 , C12N15/8241 , C12Y301/03011 , Y02A40/146
摘要： The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important characteristics in plants. More specifically, the present invention concerns a method for improving yield-related traits, such as enhanced yield and/or enhanced growth, or modified content of storage compounds in plants by modulating expression in a plant of a nucleic acid encoding a GRP (Growht Related Protein) polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding a GRP polypeptide, which plants have improved characterisitics relative to control plants. The invention also provides hitherto unknown GRP-encoding nucleic acids, and constructs comprising the same, useful in performing the methods of the invention.
摘要翻译：本发明一般涉及分子生物学领域，涉及增强植物中各种经济上重要特征的方法。更具体地，本发明涉及通过调节植物中编码GRP的核酸的表达来改善产量相关性状的方法，例如提高产量和/或增强生长或植物中储存化合物的修饰含量（Growht Related 蛋白质）多肽。本发明还涉及具有编码GRP多肽的核酸调节表达的植物，该植物相对于对照植物具有改进的特征。本发明还提供了迄今为止未知的GRP编码核酸和包含其的构建体，其可用于实施本发明的方法。

8. 发明申请

WO2006100112A1 PLANTS HAVING INCREASED YIELD AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有增加的产量的植物及其制备方法
公开(公告)号：WO2006100112A1
公开(公告)日：2006-09-28
申请号：PCT/EP2006/002895
申请日：2006-03-24
申请人： CROPDESIGN N.V. , FRANKARD, Valerie , MIRONOV, Vladimir
发明人： FRANKARD, Valerie , MIRONOV, Vladimir
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N15/8261 , Y02A40/146
摘要： The present invention concerns a method for increasing plant yield relative to corresponding wild type plants. More specifically, the present invention concerns a method for increasing plant yield comprising introducing into a plant a nucleic acid encoding a cyclin D3 (CYCD3) polypeptide under the control of a promoter capable of preferentially expressing the nucleic acid in the endosperm of seeds. The present invention also concerns plants comprising an isolated nucleic acid encoding a CYCD3 polypeptide under the control of a promoter capable of preferentially expressing the nucleic acid in the endosperm of seeds, which plants have increased yield relative to corresponding wild type plants. The invention also provides constructs useful in the methods of the invention.
摘要翻译：本发明涉及相对于相应野生型植物提高植物产量的方法。更具体地说，本发明涉及一种用于增加植物产量的方法，包括在能够优先在种子的胚乳中表达核酸的启动子的控制下向植物中引入编码细胞周期蛋白D3（CYCD3）多肽的核酸。本发明还涉及包含编码CYCD3多肽的分离的核酸的植物，所述核酸在能够优先在种子的胚乳中表达核酸的启动子控制下，该植物相对于相应的野生型植物具有增加的产量。本发明还提供了可用于本发明方法的构建体。

9. 发明申请

WO2006008271A1 PLANTS HAVING IMPROVED GROWTH CHARACTERISTICS AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改进的生长特性的植物及其制备方法
公开(公告)号：WO2006008271A1
公开(公告)日：2006-01-26
申请号：PCT/EP2005/053398
申请日：2005-07-14
申请人： CROPDESIGN N.V. , FRANKARD, Valerie , MIRONOV, Vladimir
发明人： FRANKARD, Valerie , MIRONOV, Vladimir
IPC分类号： C12N15/82
CPC分类号： C12N15/8262 , C12N9/1205 , C12N15/8261 , Y02A40/146
摘要： The present invention concerns a method for improving growth characteristics of plants by increasing activity and/or expression in a plant of an SnRK2 kinase or a homologue thereof. One such method comprises introducing into a plant an SnRK2 nucleic acid molecule or functional variant thereof. The invention also relates to transgenic plants having improved growth characteristics, which plants have modulated expression of a nucleic acid encoding an SnRK2 kinase. The present invention also concerns constructs useful in the methods of the invention.
摘要翻译：本发明涉及通过增加SnRK2激酶或其同源物的植物中的活性和/或表达来改善植物生长特性的方法。一种这样的方法包括向植物中引入SnRK2核酸分子或其功能变体。本发明还涉及具有改善的生长特性的转基因植物，该植物已经调节了编码SnRK2激酶的核酸的表达。本发明还涉及可用于本发明方法的构建体。

10. 发明申请

WO2005049646A2 PLANTS HAVING MODIFIED GROWTH CHARACTERISTICS AND A METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有改良生长特性的植物及其制备方法
公开(公告)号：WO2005049646A2
公开(公告)日：2005-06-02
申请号：PCT/EP2004/053030
申请日：2004-11-19
申请人： CROPDESIGN N.V. , FRANKARD, Valerie , MIRONOV, Vladimir
发明人： FRANKARD, Valerie , MIRONOV, Vladimir
IPC分类号： C07K14/415
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The present invention concerns a method for modifying the growth characteristics of a plant relative to corresponding wild type plants, comprising modifying expression in a plant of a seedy1 nucleic acid and/or modifying the level and/or activity in a plant of a seedy1 protein. The invention also concerns novel constructs and novel seedy1 nucleic acid and protein sequences.
摘要翻译：本发明涉及一种改变植物相对于相应野生型植物的生长特性的方法，其包括改变种子1核酸的植物中的表达和/或修饰seedy1蛋白的植物中的水平和/或活性。本发明还涉及新型构建体和新颖的seedy1核酸和蛋白质序列。

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