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1. 发明申请

WO2007069827A1 PHARMACEUTICAL COMPOSITION WITH EXTENDED RELEASE LAYER AND FAST RELEASE LAYER FOR TREATMENT OF HYPERLIPIDEMIA AND ARTERIOSCLEROSIS 审中-公开
标题翻译：具有扩展释放层和快速释放层的药物组合物用于治疗高磷脂酰胆碱和血栓形成
公开(公告)号：WO2007069827A1
公开(公告)日：2007-06-21
申请号：PCT/KR2006/004738
申请日：2006-11-13
申请人： CHONG KUN DANG PHARMACEUTICAL CORP. , SHIN, Hee Jong , KI, Min Hyo , LEE, Jin Woo , KIM, Byoung Su
发明人： SHIN, Hee Jong , KI, Min Hyo , LEE, Jin Woo , KIM, Byoung Su
IPC分类号： A61K9/22 , A61P9/10
CPC分类号： A61K9/209
摘要： The present invention provides a pharmaceutical composition comprising a therapeutically amount of nicotinic acid and a nicotinic acid compound or mixtures thereof in a sustained release form and a therapeutically amount of a HMG-CoA reductase inhibitor in a fast release form which can optimally treat hyperlipidemia and arteriosclerosis by minimizing the interaction of two drugs. The pharmaceutical composition of the present invention comprising a coated two- layer tablet a) one sustained release layer containing nicotinic acid and a nicotinic acid compound or mixtures thereof, together with a sustained release polymer and b) another fast release layer containing a HMG-CoA reductase inhibitor, a film- or layer- forming agent, a re- crystallization inhibitor and a plasticizer, can minimize the interaction of the two drugs via controlled release profile and treat optimally hyperlipidemia and arteriosclerosis.
摘要翻译：本发明提供药物组合物，其包含治疗量的烟酸和烟酸化合物或其缓释形式的混合物和治疗量的快速释放形式的HMG-CoA还原酶抑制剂，其可以最佳地治疗高脂血症和动脉硬化通过最小化两种药物的相互作用。本发明的药物组合物包含包被的两层片剂a）一个含有烟酸和烟酸化合物或其混合物的持续释放层以及持续释放聚合物，以及b）包含HMG-CoA的另一快速释放层还原酶抑制剂，成膜剂或成层剂，再结晶抑制剂和增塑剂，可以通过控制释放曲线最小化两种药物的相互作用，并治疗最佳高脂血症和动脉硬化。

2. 发明申请

WO2007035028A1 NOVEL RESINATE COMPLEX OF S-CLOPIDOGREL AND PRODUCTION METHOD THEREOF 审中-公开
标题翻译：新型树脂复合材料及其生产方法
公开(公告)号：WO2007035028A1
公开(公告)日：2007-03-29
申请号：PCT/KR2006/003346
申请日：2006-08-24
申请人： CHONG KUN DANG PHARMACEUTICAL CORP. , SHIN, Hee Jong , KI, Min Hyo , CHOI, Mee Hwa
发明人： SHIN, Hee Jong , KI, Min Hyo , CHOI, Mee Hwa
IPC分类号： C07D495/04
CPC分类号： A61K31/4365 , A61K47/585 , C07D495/04
摘要： The present invention is a novel resinate complex of (+)-clopidogrel optical isomer, wherein the (+)-clopidogrel isomer is bounded to a water-soluble cation exchange resin having sulfonic acid groups. The novel resinate complex has recognized some advantages in that (1) its chemical structure is stable, and (2) it can be formulated into a solid form that may provide taste-masking capabilities associated with bitter drugs (e.g., strong irritation, bitterness and sour taste), thus requiring no drink of water.
摘要翻译：本发明是（+） - 氯吡格雷旋光异构体的新型树脂酸复合物，其中（+） - 氯吡格雷异构体与具有磺酸基的水溶性阳离子交换树脂结合。新型树脂酸复合物已经认识到一些优点：（1）其化学结构是稳定的，和（2）它可以配制成固体形式，其可以提供与苦味药相关的味道掩蔽能力（例如，强刺激，苦味和酸味），因此不需要饮用水。

3. 发明申请

WO2006088305A1 GASTRIC-RETENTIVE CONTROLLED RELEASE MONO-MATRIX TABLET 审中-公开
标题翻译：气体保持控制释放单矩阵片
公开(公告)号：WO2006088305A1
公开(公告)日：2006-08-24
申请号：PCT/KR2006/000512
申请日：2006-02-14
申请人： CHONG KUN DANG PHARMACEUTICAL CORP. , SHIN, Hee Jong , KI, Min Hyo , YOON, Bok-young , AN, Sung Won
发明人： SHIN, Hee Jong , KI, Min Hyo , YOON, Bok-young , AN, Sung Won
IPC分类号： A61K9/20
CPC分类号： A61K9/0065 , A61K9/0007 , A61K9/2031
摘要： The present invention relates to a gastric-retentive controlled release mono-matrix tablet composition, comprising: a) at least one pharmacologically active substance; b) hydrogel-forming materials consisting of polyethylene oxide and at least one component selected from poloxamers and colloidal silica; and c) a carbon dioxide-generating material. The composition of the present invention floats in gastric juice and can continuously release the active substance in the stomach at a constant rate for at least 2 hours.
摘要翻译：本发明涉及一种胃保持性控释单基质片组合物，其包含：a）至少一种药理学活性物质; b）由聚环氧乙烷和至少一种选自泊洛沙姆和胶体二氧化硅的组分组成的水凝胶形成材料; 和c）产生二氧化碳的材料。本发明的组合物漂浮在胃液中，可以以恒定速率连续释放胃中的活性物质至少2小时。

4. 发明申请

WO2006033505A1 PAROXETINE CHOLATE OR CHOLIC ACID DERIVATIVE SALTS, AND COMPOSITION COMPRISING PAROXETINE AND CHOLIC ACID OF CHOLIC ACID DERIVATIVES 审中-公开
标题翻译：异黄酮或胆酸衍生物，以及包含胆酸和胆酸的化合物的组合物
公开(公告)号：WO2006033505A1
公开(公告)日：2006-03-30
申请号：PCT/KR2004/003477
申请日：2004-12-28
申请人： CHONG KUN DANG PHARMACEUTICAL CORP. , LEE, Sang Joon , SHIN, Hee Jong , KI, Min Hyo , LEE, Su Kyoung , KIM, Bok Young , LEE, Hong Woo
发明人： LEE, Sang Joon , SHIN, Hee Jong , KI, Min Hyo , LEE, Su Kyoung , KIM, Bok Young , LEE, Hong Woo
IPC分类号： C07D405/12
CPC分类号： C07D405/12 , C07J43/00
摘要： Disclosed herein is a paroxetine cholate or cholic acid derivative salt and a composition comprising paroxetine and cholic acid or a derivative thereof. Further disclosed is a pharmaceutical composition comprising the paroxetine salt or the composition. The pharmaceutical composition can be formulated into an oral preparation for swallowing without water as an orally disintegrating tablet for paroxetine.
摘要翻译：本文公开了帕罗西汀胆酸盐或胆酸衍生物盐和包含帕罗西汀和胆酸或其衍生物的组合物。还公开了包含帕罗西汀盐或组合物的药物组合物。作为帕罗西汀的口腔崩解片剂，可以将药物组合物配制成无水的口服制剂。

5. 发明申请

WO2003082845A1 INCLUSION COMPOUNDS OF FUMAGILLOL DERIVATIVE OR ITS SALT, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME 审中-公开
标题翻译： FUMAGILLOL衍生物或其盐的包含化合物和包含其的药物组合物
公开(公告)号：WO2003082845A1
公开(公告)日：2003-10-09
申请号：PCT/KR2002/000583
申请日：2002-04-03
申请人： CHONG KUN DANG PHARMACEUTICAL CORP. , KIM, Jae Hyun , LEE, Su Kyung , CHOI, Won Kyu , LIM, Jong Lae , AHN, Soon Kil , SHIN, Hee Jong , HONG, Chung Il
发明人： KIM, Jae Hyun , LEE, Su Kyung , CHOI, Won Kyu , LIM, Jong Lae , AHN, Soon Kil , SHIN, Hee Jong , HONG, Chung Il
IPC分类号： C07D303/08
CPC分类号： A61K47/48969 , A61K9/0019 , A61K31/336 , A61K47/02 , A61K47/6951 , B82Y5/00 , C07D303/16 , C07D303/20 , C07D303/28 , C07D407/14 , C08B37/0015 , C08L5/16
摘要： The present invention relates with inclusion compound of fumagillol derivative or its salt with hydroxypropyl-β-cyclodextrin or sulfobutylether-7-β-cyclodextrin, and pharmaceutical composition comprising the same, and the inclusion compound according to the present invention has superior water solubility, stability while exhibiting low toxicity, thus is valuable as anticancer agent or inhibitor of tumor metastasis.
摘要翻译：本发明涉及烟曲霉醇衍生物或其盐与羟丙基-β-环糊精或磺丁基醚-7-β-环糊精的包合物，以及包含其的药物组合物，本发明的包合物具有优异的水溶性，稳定性同时显示低毒性，因此作为抗癌剂或肿瘤转移抑制剂是有价值的。

6. 发明申请

WO2006052098A1 THE INJECTION OF TACROLIMUS 审中-公开
标题翻译：注射TACROLIMUS
公开(公告)号：WO2006052098A1
公开(公告)日：2006-05-18
申请号：PCT/KR2005/003814
申请日：2005-11-11
申请人： CHONG KUN DANG PHARMACEUTICAL CORP. , LEE, Sang Joon , SHIN, Hee Jong , LEE, Seok Kyu , YUN, Ji Hun
发明人： LEE, Sang Joon , SHIN, Hee Jong , LEE, Seok Kyu , YUN, Ji Hun
IPC分类号： A61K9/08
CPC分类号： A61K47/10 , A61K9/0019 , A61K9/08 , A61K47/14
摘要： This invention relates to tacrolimus injection comprising tacrolimus as an active ingredient, macrogol 15 hydroxystearate as a surfactant and a non-aqueous solvent.
摘要翻译：本发明涉及他克莫司注射剂，其包含他克莫司作为活性成分，羟基硬脂酸羟肟酸锌15作为表面活性剂和非水溶剂。

7. 发明申请

WO2006057531A1 LIGHT EMITTING MAT FOR VEHICLES 审中-公开
标题翻译：车辆发光灯
公开(公告)号：WO2006057531A1
公开(公告)日：2006-06-01
申请号：PCT/KR2005/004006
申请日：2005-11-26
申请人： KIM, Sean , SHIN, Hee Kwan , KIM, Eun Suk , SHIN, Hee Jong
发明人： KIM, Eun Suk , SHIN, Hee Jong
IPC分类号： B60N3/04
CPC分类号： B60N3/048 , B60Q3/20 , B60Q3/54 , B60Q3/745 , B60Q2500/10
摘要： The present invention relates to a light -emitting mat for vehicles in which a plurality of light -emitting diodes or an electro- luminescent sheet having a predetermined size is installed on an edge or a bottom of a transparent decoration plate having predetermined decorative patterns, so that the decorative patterns shine with a variety of colors as light emitted from a light -emit ting source is radiated thereto when electric power is supplied to the light-emitting diodes or an electro- luminescent sheet. An object of the present invention is to provide a light -emit ting mat for vehicles that can meet a user's desire for beauty and a variety of functions. The light-emitting mat is made of a transparent plastic material, instead of an opaque material with dark and dull colors, which are typical for conventional mats for vehicles, and has predetermined decorative patterns that shine with a variety of colors using a plurality of light -emitting diodes or an electro- luminescent sheet. Accordingly, decorative effect of the mat according to the present invention is highly improved.
摘要翻译：本发明涉及一种用于车辆的发光垫，其中多个发光二极管或具有预定尺寸的电致发光片安装在具有预定装饰图案的透明装饰板的边缘或底部上，因此，当向发光二极管或电致发光片提供电力时，装饰图案以各种颜色发光，当从光源发出的光被照射到其上。本发明的目的是提供一种能够满足用户对美容和各种功能的渴望的用于车辆的光照射垫。发光垫由透明塑料材料制成，而不是具有暗色和暗色的不透明材料，这是典型的用于车辆的常规垫片，并且具有预定的装饰图案，其使用多种光线以各种颜色照射发光二极管或电致发光片。因此，根据本发明的垫的装饰效果大大提高。

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