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1. 发明申请

WO2008063492A1 DYNAMIC MORPHOLOGY BASED ATRIAL AUTOMATIC THRESHOLD 审中-公开
标题翻译：基于动态形态学的ATRIAL自动阈值
公开(公告)号：WO2008063492A1
公开(公告)日：2008-05-29
申请号：PCT/US2007/023820
申请日：2007-11-15
申请人： CARDIAC PACEMAKERS, INC. , GARG, Ankur , ENROOTH, Eric , BOHN, Derek, D.
发明人： GARG, Ankur , ENROOTH, Eric , BOHN, Derek, D.
IPC分类号： A61N1/37 , A61N1/368
CPC分类号： A61N1/371 , A61N1/3712
摘要： Methods and systems for performing capture threshold tests are described. During an initialization procedure a capture detection interval and capture detection threshold are determined based on peak values of cardiac signals sensed following the supracapture threshold initialization pulses. Following initialization, a plurality of pacing pulses to the atrium are delivered and the peak values of the cardiac signals sensed following each of the plurality of pacing pulses are determined. The peak values are compared to the pacing artifact threshold and the capture detection threshold. A timing of each of the peak values is compared to the capture detection interval. For each pacing pulse, discrimination between a captured response, a noncaptured response, and a fusion response is based on the peak value and timing comparisons.
摘要翻译：描述用于执行捕获阈值测试的方法和系统。在初始化过程期间，捕获检测间隔和捕获检测阈值是基于超标准阈值初始化脉冲之后感测的心脏信号的峰值来确定的。在初始化之后，传送到心房的多个起搏脉冲，并且确定在多个起搏脉冲之后检测到的心脏信号的峰值。将峰值与起搏伪像阈值和捕获检测阈值进行比较。将每个峰值的定时与捕获检测间隔进行比较。对于每个起搏脉冲，捕获的响应，非捕获响应和融合响应之间的区别基于峰值和时序比较。

2. 发明申请

WO2018118568A1 LEARNING TECHNIQUES FOR CARDIAC ARRHYTHMIA DETECTION 审中-公开
公开(公告)号：WO2018118568A1
公开(公告)日：2018-06-28
申请号：PCT/US2017/066050
申请日：2017-12-13
申请人： CARDIAC PACEMAKERS, INC.
发明人： HERRMANN, Keith, L. , SAHA, Sunipa , SHARMA, Arjun, D. , PERSCHBACHER, David, L. , BOHN, Derek, D. , SIEJKO, Krzysztof, Z.
IPC分类号： A61B5/00 , A61B5/0452
摘要： This document discusses, among other things, systems and methods to adjust arrhythmia detection using physiological information of a patient, including detecting a candidate cardiac event about a threshold, displaying the detected candidate cardiac event to a user, receiving user information about the detected candidate cardiac event, and adjusting an arrhythmia detection threshold based upon the received user information.

3. 发明申请

WO2006127323A1 RETROGRADE ATRIAL SENSING FOR IDENTIFYING SUB-THRESHOLD ATRIAL PACING 审中-公开
标题翻译：用于识别亚临界。IAL。。。。。。。。。。。。。。。。。。。。
公开(公告)号：WO2006127323A1
公开(公告)日：2006-11-30
申请号：PCT/US2006/018810
申请日：2006-05-12
申请人： CARDIAC PACEMAKERS, INC.
发明人： BOHN, Derek, D. , GANDHI, Rajesh, K.
IPC分类号： A61N1/37 , A61N1/368
CPC分类号： A61N1/3712 , A61N1/368 , A61N1/3714
摘要： Systems provide for delivering a pacing pulse to an atrium during a cardiac cycle. A retrograde P-wave may be identified during the cardiac cycle, indicative of subthreshold atrial pacing. Delivery of the pacing pulse to the atrium may be adjusted in a subsequent cardiac cycle in response to identifying the retrograde P-wave. Adjusting delivery of the pacing pulse may involve initiating an atrial capture threshold test, temporarily increasing one or both of the pacing pulse amplitude and pulse width, and/or re-evaluating one or both of the pacing pulse amplitude and pulse width. Adjusting delivery of the pacing pulse may also involve altering the timing of a scheduled atrial capture threshold test. During an atrial capture threshold test, a retrograde P-wave template may be generated in response to atrial non-capture sensed during the atrial capture threshold test, and used to identify subsequent retrograde P-waves.
摘要翻译：系统提供在心动周期期间向心房递送起搏脉冲。可以在心动周期期间鉴定出逆行P波，表示心律起搏的亚阈值。响应于识别逆行P波，可以在随后的心动周期中调整起搏脉冲到心房的输送。调节起搏脉冲的传送可以包括启动心房捕获阈值测试，暂时增加起搏脉冲幅度和脉冲宽度中的一个或两个，和/或重新评估起搏脉冲幅度和脉冲宽度中的一个或两个。调整起搏脉冲的传递也可能涉及改变调度的心房捕获阈值测试的时序。在心房捕获阈值测试期间，可以响应于在心房捕获阈值测试期间感测到的心房非捕获而产生逆行P波模板，并且用于识别随后的逆行P波。

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