会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 5. 发明申请
    • CONTROLLED-RELEASE DRUG DELIVERY SYSTEM
    • 控制释放药物输送系统
    • WO2004066939A2
    • 2004-08-12
    • PCT/US2004/002142
    • 2004-01-26
    • SARNOFF CORPORATIONDEVENEY, ThomasPAWLO, GeorgeFRIEND, DavidZIEGLER, Kerrie
    • DEVENEY, ThomasPAWLO, GeorgeFRIEND, DavidZIEGLER, Kerrie
    • A61K
    • A61K9/2072
    • A controlled-release drug delivery system advantageously includes an open-ended, inflexible sleeve, at least two controlled-release layers and two open-center caps. Each controlled-release layer abuts a sealing surface that is located within and near each end of the sleeve. The caps seal each controlled-release layer against the abutting sealing surface. One or more dose units of drug are disposed in a region that is formed between the controlled-release layers. The controlled-release layers dissolve, at a predetermined rate, by the action of body fluids that are in contact with those layers through the center of the caps. Release of drug is delayed at least until the controlled-release layers dissolve. The dose unit itself, which is advantageously a core, can be tailored to provide an extended period of drug release. One or more dose units that provide an immediate release component can also be disposed near each end of the sleeve.
    • 控释药物递送系统有利地包括开放式,非弹性套管,至少两个控制释放层和两个开放中心帽。 每个控制释放层邻接位于套筒每个端部内和附近的密封表面。 盖子密封每个控释层与抵靠的密封表面。 一个或多个剂量单位的药物设置在形成在控释层之间的区域中。 受控释放层以预定的速率通过与这些层接触的体液的动作溶解,通过帽的中心。 药物的释放至少延迟至控释层溶解。 剂量单位本身(其有利地为核心)可以被定制以提供长时间的药物释放。 提供立即释放组分的一个或多个剂量单位也可以设置在套筒的每个端部附近。