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1. 发明申请

WO2005003715A2 INFORMATION ACQUISITION METHOD, INFORMATION ACQUISITION APPARATUS AND DISEASE DIAGNOSIS METHOD 审中-公开
标题翻译：信息获取方法，信息获取装置和疾病诊断方法
公开(公告)号：WO2005003715A2
公开(公告)日：2005-01-13
申请号：PCT/JP2004/009788
申请日：2004-07-02
申请人： CANON KABUSHIKI KAISHA , HASHIMOTO, Hiroyuki , KUGE, Katsuaki , KOMATSU, Manabu , NAKAMURA, Kumi , BAN, Kazuhiro , IMAMURA, Takeshi , KOBAYASHI, Shin
发明人： HASHIMOTO, Hiroyuki , KUGE, Katsuaki , KOMATSU, Manabu , NAKAMURA, Kumi , BAN, Kazuhiro , IMAMURA, Takeshi , KOBAYASHI, Shin
IPC分类号： G01N
CPC分类号： G01N33/6848 , H01J49/04 , H01J49/40
摘要： An information acquisition method for acquiring information on a target object, that includes a step of promoting ionization of the target object using a substance for promoting ionization of the target object to cause the target object to emit, and a step of acquiring information on the mass of the flew target object using time-of-flight secondary ion mass spectrometry.
摘要翻译：一种用于获取关于目标对象的信息的信息获取方法，包括使用促进目标对象的电离的物质促进目标物体的离子化以使目标对象发射的步骤，以及获取关于物体的信息的步骤的步骤的飞行目标物体使用飞行时间二次离子质谱法。

2. 发明申请

WO2005071414A2 KIT FOR IMMOBILIZING ORGANIC SUBSTANCE, ORGANIC SUBSTANCE-IMMOBILIZED STRUCTURE, AND MANUFACTURING METHODS THEREFOR 审中-公开
标题翻译：用于固定有机物质，有机物质固定结构及其制造方法的工具包
公开(公告)号：WO2005071414A2
公开(公告)日：2005-08-04
申请号：PCT/JP2005/001316
申请日：2005-01-25
申请人： CANON KABUSHIKI KAISHA , BAN, Kazuhiro , SHIOTSUKA, Hidenori , IMAMURA, Takeshi
发明人： BAN, Kazuhiro , SHIOTSUKA, Hidenori , IMAMURA, Takeshi
IPC分类号： G01N33/543
CPC分类号： G01N33/54353 , G01N33/551
摘要： To provide an organic substance-immobilized structure employing a novel immobilizing technique and a manufacturing method thereof using the novel immobilizing technique, where, when an organic substance, particularly a biological substance is immobilized on the surface of a substrate, the organic substance, particularly the biological substance can be stably immobilized on the surface of the substrate through orientation of the organic substance, particularly the biological substance suitable for exerting physiological functions thereof. At least part of the substrate's surface is constructed of one or more substrates containing aluminum oxide. The immobilization of the organic substance to the surface of the substrate is carried out by binding at least part of the binding domain to the surface of the substrate through a binding domain containing a peptide having an affinity to aluminum oxide and composed of at least one or more amino acids, which is coupled with the organic substance.
摘要翻译：为了提供采用新型固定化技术的有机物质固定化结构及其制造方法，其中，当将有机物质，特别是生物物质固定在基材表面上时，有机物质，特别是生物物质可以通过有机物质，特别是适于发挥其生理功能的生物物质的取向，稳定地固定在基材的表面上。衬底表面的至少一部分由含有氧化铝的一个或多个衬底构成。有机物质固定到底物的表面是通过结合结构域与底物的表面结合而进行的，所述结合结构域含有与氧化铝具有亲和性的肽，并且由至少一个或多个更多的氨基酸，其与有机物质偶联。

3. 发明申请

WO2007026972A3 BINDING PROTEIN MOLECULE 审中-公开
公开(公告)号：WO2007026972A3
公开(公告)日：2007-03-08
申请号：PCT/JP2006/317808
申请日：2006-09-01
申请人： CANON KABUSHIKI KAISHA , IMAMURA, Takeshi , SHIOTSUKA, Hidenori , BAN, Kazuhiro , IBII, Takahisa
发明人： IMAMURA, Takeshi , SHIOTSUKA, Hidenori , BAN, Kazuhiro , IBII, Takahisa
IPC分类号： C07K16/40 , C07K16/18 , C07K16/44 , C07K17/14 , G01N33/553
摘要： A binding protein molecule, characterized in that it has a first domain having a binding site to an inhibitor of non-specific adsorption in which the domain comprises a part of the variable region of an antibody as the binding site and a second domain having a binding site to a target substance in which the domain comprises a part of the variable region of an antibody as the binding site, wherein the first and second domains are bound via a linker.

4. 发明申请

WO2009145359A1 GRAFT POLYMER-CONTAINING SUBSTRATE, METHOD FOR PRODUCING THE SAME, TARGET SUBSTANCE-DETECTING ELEMENT, AND TARGET SUBSTANCE DETECTION KIT 审中-公开
标题翻译：含聚合物基材，其生产方法，目标物质检测元件和目标物质检测试剂盒
公开(公告)号：WO2009145359A1
公开(公告)日：2009-12-03
申请号：PCT/JP2009/060299
申请日：2009-05-29
申请人： CANON KABUSHIKI KAISHA , BAN, Kazuhiro , MINAMI, Masato , KISHI, Mayuko
发明人： BAN, Kazuhiro , MINAMI, Masato , KISHI, Mayuko
IPC分类号： C08F292/00 , G01N33/543
CPC分类号： G01N33/54353 , C08F2/38 , C08F8/06 , C08F292/00 , C08F2438/01 , G01N33/54393 , C08F222/1006
摘要： The invention provides a graft polymer-containing substrate for reducing nonspecific adsorption of impurities as well as specifically capturing a target substance by forming a polymer membrane on a substrate and immobilizing a target substance-capturing body that captures the target substance thereon, and a method for producing the same. Furthermore, the present invention provides a target substance-detecting element and detection kit that detect substance alone with high sensitivity by using the above-mentioned graft polymer-containing substrate.
摘要翻译：本发明提供了一种含有接枝聚合物的底物，用于通过在基材上形成聚合物膜并固定捕获其上的目标物质的靶物质捕获体来减少杂质的非特异性吸附以及特异性捕获目标物质，以及用于生产相同。此外，本发明提供了通过使用上述含有接枝聚合物的基板以高灵敏度检测物质的目标物质检测元件和检测试剂盒。

5. 发明申请

WO2007043498A1 SUBSTRATE WITH BINDING FUNCTIONAL GROUP 审中-公开
标题翻译：基座与绑定功能组
公开(公告)号：WO2007043498A1
公开(公告)日：2007-04-19
申请号：PCT/JP2006/320159
申请日：2006-10-03
申请人： CANON KABUSHIKI KAISHA , BAN, Kazuhiro , NAKAHAMA, Kazumichi , OGAWA, Miki
发明人： BAN, Kazuhiro , NAKAHAMA, Kazumichi , OGAWA, Miki
IPC分类号： G01N33/543
CPC分类号： B82Y30/00 , B82Y15/00 , G01N33/54393
摘要： A structural member having a binding functional group on a substrate for binding a capturing molecule capable of capturing a target substance, characterized in that the substrate binds to one end of a polymer which includes at the other end those to which the binding functional group is bound and those to which a suppressing functional group for suppressing adsorption of biological molecules to the structural member and that the suppressing functional group is also bound to a side chain of the polymer.
摘要翻译：一种在底物上具有结合能捕获靶物质的捕获分子的结合官能团的结构部件，其特征在于，所述底物与聚合物的一端结合，所述聚合物的另一端包含结合官能团所结合的那些以及抑制生物分子吸附到结构构件上的抑制官能团，抑制官能团也与聚合物的侧链结合的那些。

6. 发明申请

WO2006080571A1 MAGNETIC SENSOR 审中-公开
标题翻译：磁传感器
公开(公告)号：WO2006080571A1
公开(公告)日：2006-08-03
申请号：PCT/JP2006/301905
申请日：2006-01-30
申请人： CANON KABUSHIKI KAISHA , IKEDA, Takashi , BAN, Kazuhiro
发明人： IKEDA, Takashi , BAN, Kazuhiro
IPC分类号： G01N27/72 , G01N33/543 , G01R33/09 , H01L43/08
CPC分类号： G01R33/12 , B82Y15/00 , B82Y25/00 , B82Y30/00 , G01R33/09 , G01R33/1269 , H01L27/22
摘要： The invention is to provide a magnetic sensor capable of detecting magnetic particles over a wide range of number and of suppressing an increase in a detection area. The magnetic sensor includes a detection part, a selecting device connected electrically to an end of the detecting part, and a sensing amplifier for receiving a signal from the detecting part, wherein the detecting part includes at least two magnetoresistive films serially connected.
摘要翻译：本发明提供一种能够在宽范围内检测磁性粒子并抑制检测区域增加的磁传感器。磁传感器包括检测部分，与检测部分的端部电连接的选择装置，以及用于接收来自检测部分的信号的感测放大器，其中检测部分包括串联连接的至少两个磁阻膜。

7. 发明申请

WO2009020220A1 STRUCTURAL MEMBER AND METHOD OF PRODUCING THE STRUCTURAL MEMBER 审中-公开
标题翻译：结构构件和生产结构构件的方法
公开(公告)号：WO2009020220A1
公开(公告)日：2009-02-12
申请号：PCT/JP2008/064380
申请日：2008-08-05
申请人： CANON KABUSHIKI KAISHA , BAN, Kazuhiro , MINAMI, Masato , CHIDA, Mayuko
发明人： BAN, Kazuhiro , MINAMI, Masato , CHIDA, Mayuko
IPC分类号： B32B27/30 , C08F4/40 , C09D4/00
CPC分类号： C09D4/00 , C08F2/38
摘要： The invention provides a structural member having an excellent ability to prevent the nonspecific adsorption of a biomolecule and a labeling substance to the surface of a substrate, and a method of producing the structural member. The structural member includes a substrate and a polymer present on a surface of the substrate, in which the polymer is formed from a polymer of a specific multi-vinyl monomer, and has a crosslinked structure.
摘要翻译：本发明提供了具有优异的防止生物分子和标记物质对基材表面的非特异性吸附的能力的结构部件及其制造方法。结构构件包括基材和存在于基材表面上的聚合物，其中聚合物由特定的多乙烯基单体的聚合物形成并具有交联结构。

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