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    • 5. 发明申请
    • METHODS AND BIOMARKERS FOR DIAGNOSING AND MONITORING PSYCHOTIC DISORDERS
    • 用于诊断和监测心理疾病的方法和生物标志物
    • WO2007045865A2
    • 2007-04-26
    • PCT/GB2006/003870
    • 2006-10-18
    • CAMBRIDGE ENTERPRISE LIMITEDBAHN, SabineHUANG, Jeffrey, J.TSANG, Tsz
    • BAHN, SabineHUANG, Jeffrey, J.TSANG, Tsz
    • G01R33/465
    • B82Y15/00B82Y5/00G01R33/465Y10T436/24
    • The invention relates to methods of diagnosing or monitoring a psychotic disorder in a subject comprising providing a test biological sample from the subject, performing spectral analysis on said test biological sample to provide one or more spectra, and, comparing the one or more spectra with one or more control spectra. The invention also relates to methods for diagnosing or monitoring psychotic disorders such as schizophrenic or bipolar disorders, comprising measuring the level of one or more biomarkers present in a biological sample taken from a test subject, said biomarkers being selected from the group consisting of transthyretin, ApoA1 ,: VLDL, LDL and aromatic species such as plasma proteins. The invention also relates to sensors, biosensors, multi-analyte panels, arrays, assays and kits for performing methods of the invention.
    • 本发明涉及诊断或监测受试者中的精神病性障碍的方法,包括从受试者提供测试生物样品,对所述测试生物样品进行光谱分析以提供一个或多个光谱,以及将一个或多个光谱与一个或多个光谱进行比较 或更多的控制光谱。 本发明还涉及用于诊断或监测精神病性疾病如精神分裂症或双相性精神障碍的方法,包括测量取自受试者的生物样品中存在的一种或多种生物标志物的水平,所述生物标志物选自转甲状腺素蛋白, ApoA1,VLDL,LDL和芳族物质如血浆蛋白。 本发明还涉及用于执行本发明方法的传感器,生物传感器,多分析物面板,阵列,测定和试剂盒。