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    • 2. 发明申请
    • ANTI-MICROBIAL WIPES
    • 抗微生物制品
    • WO2011064554A1
    • 2011-06-03
    • PCT/GB2010/002191
    • 2010-11-26
    • BYOTROL PLCFALDER, Stephen, BrianFRANCIS, Thomas, TrevorYATES, John
    • FALDER, Stephen, BrianFRANCIS, Thomas, TrevorYATES, John
    • A01N33/12C11D1/62C11D1/835C11D3/00C11D17/04
    • C11D3/48A01N33/12C11D17/049A01N25/34A01N2300/00
    • The present invention provides an anti-microbial wipe comprising a substrate comprising from 1 to 100% by weight of a cellulosic material and incorporating a composition comprising (i) an anti-microbial component; (ii) a non-ionic surfactant; (iii) a polar solvent; and optionally (iv) a hydrophobic material; wherein the anti-microbial component (i) comprises (a) at least one quaternary ammonium compound of formula (A) R 1 R 2 R 3 R 4 N + X - , wherein R 1 , R 2 , R 3 and R 4 represent, independently a substituted or unsubstituted and/or straight chain or branched and/or interrupted or uninterrupted alkyl, aryl, alkylaryl, arylalkyl, cycloalkyl, heterocyclyl or alkenyl group, and wherein the total number of carbon atoms in the groups R 1 , R 2 , R 3 and R 4 is at least 4; wherein the substituents for the groups R 1 , R 2 , R 3 and R 4 are selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, heterocyclyl, substituted heterocyclyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkylaryl, substituted alkylaryl, arylalkyl, substituted arylalkyl, F, Cl, Br, I, -OR', -NR'R", -CF 3 , -CN, -NO 2 , -C 2 R', - SR', -N 3 , -C(=O)NR'R", -NR'C(=O) R", -C(=O)R', -C(=O)OR', -OC(=O)R', -O(CR'R") r C(=O)R' -O(CR'R") r NR"C(=O)R', -O(CR'R") r NR"SO2R', -OC(=O)NR'R", -NR'C(=O)OR", -SO 2 R', - SO 2 NR'R", and -NR'SO 2 R"; wherein R' and R" are individually hydrogen, C 1 -C 8 alkyl, cycloalkyl, heterocyclyl, aryl, or arylalkyl, and r is an integer from 1 to 6, or R' and R" together form a cyclic functionality; wherein the term "substituted" as applied to alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, alkylaryl and arylalkyl refers to the substituents described above, starting with F and ending with -NR'SO 2 R"; and wherein X - is halide or sulphonate; and optionally (b) one or more additional anti-microbial agents, and wherein the composition is substantially free of anionic surfactant.
    • 本发明提供了一种抗微生物擦拭物,其包含基材,其包含1至100重量%的纤维素材料并掺入包含(i)抗微生物成分的组合物; (ii)非离子表面活性剂; (iii)极性溶剂; 和(iv)疏水性材料; 其中所述抗微生物组分(i)包含(a)至少一种式(A)的季铵化合物,R1R2R3R4N + X-,其中R1,R2,R3和R4独立地表示取代或未取代的和/或直链或 支链和/或中断或不间断的烷基,芳基,烷基芳基,芳基烷基,环烷基,杂环基或烯基,并且其中基团R1,R2,R3和R4中的总碳原子数至少为4; 基团R1,R2,R3和R4的取代基选自烷基,取代的烷基,烯基,取代的烯基,杂环基,取代的杂环基,环烷基,取代的环烷基,芳基,取代的芳基,烷基芳基,取代的烷基芳基, 芳基烷基,取代芳基烷基,F,Cl,Br,I,-OR', - NR'R“,-CF 3,-CN,-NO 2,-C 2 R', - SR',-N 3,-C(= O)NR 'R“,-NR'C(= O)R”,-C(= O)R', - C(= O)OR',-OC(= O)R', - O(CR'R“ rC(= O)R'-O(CR'R“)rNR”C(= O)R',-O(CR'R“)rNR”SO2R',-OC(= O)NR'R“ NR'C(= O)OR“,-SO 2 R', - SO 2 NR'R”和-NR'SO 2 R“; 其中R'和R“分别为氢,C 1 -C 8烷基,环烷基,杂环基,芳基或芳烷基,r为1至6的整数,或R'和R”一起形成环状官能团; 其中应用于烷基,烯基,杂环基,环烷基,芳基,烷基芳基和芳烷基的术语“取代的”是指以F开始并以-NR'SO 2 R“结束的上述取代基;其中X是卤化物或磺酸盐; 和任选地(b)一种或多种另外的抗微生物剂,并且其中所述组合物基本上不含阴离子表面活性剂。