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1. 发明申请

WO2009147218A1 PHARMACEUTICAL COMBINATION 审中-公开
标题翻译：药物组合
公开(公告)号：WO2009147218A1
公开(公告)日：2009-12-10
申请号：PCT/EP2009/056891
申请日：2009-06-04
申请人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH , STEFANIC, Martin Friedrich , HILBERG, Frank , KAISER, Rolf , SHAPIRO, David
发明人： STEFANIC, Martin Friedrich , HILBERG, Frank , KAISER, Rolf , SHAPIRO, David
IPC分类号： A61K31/496 , A61K31/519 , A61P35/00 , A61P3/10 , A61P17/06 , A61P19/02 , A61P25/02 , A61P9/00 , A61P11/06 , A61P27/02 , A61P1/16 , A61P43/00
CPC分类号： A61K31/519 , A61K9/4858 , A61K31/496 , A61N5/10 , A61K2300/00
摘要： The present invention relates to a pharmaceutical combination which may be useful for the treatment of diseases which involve cell proliferation, which involve migration or apoptosis of myeloma cells, which involve angiogenesis or which involve fibrosis. The invention also relates to a method for the treatment of said diseases, comprising simultaneous, separate or sequential administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
摘要翻译：本发明涉及可用于治疗涉及涉及血管生成或涉及纤维化的骨髓瘤细胞迁移或凋亡的细胞增殖的疾病的药物组合。本发明还涉及一种用于治疗所述疾病的方法，其包括以提供添加剂和协同效应的比例同时，分别或连续施用有效量的特定活性化合物和/或与放射治疗共同治疗，以及将这些特定化合物和/或放射疗法的组合使用用于制造相应的药物组合制剂。

2. 发明申请

WO2006076332A2 METHODS AND SYSTEMS FOR ORIGINATING AND SCORING A FINANCIAL INSTRUMENT 审中-公开
标题翻译：用于归档和分配财务仪器的方法和系统
公开(公告)号：WO2006076332A2
公开(公告)日：2006-07-20
申请号：PCT/US2006/000769
申请日：2006-01-11
申请人： EARN CORPORATION , SHAPIRO, David , PHILLIPS, Stuart , HENRY, Peter , DUCHESNE, Mark
发明人： SHAPIRO, David , PHILLIPS, Stuart , HENRY, Peter , DUCHESNE, Mark
IPC分类号： G06Q40/00
CPC分类号： G06Q40/06 , G06Q40/00 , G06Q40/02 , G06Q40/025
摘要： A financial instrument exchanged between an owner of real estate and a source of capital. A request for a cash payment is received from the owner. The cash payment is disbursed by the source of capital to the owner. The financial instrument is originated from the owner to the source of capital. The cash payment comprises an amount equal t a percentage of a value of the property measured upon the origination of the financial instrument. The financial instrument comprises an obligation of the owner to pay to the source of capital, at a time associated with a triggering event, a single payment in an amount equal to a percentage of a value of the real estate (including any amounts encumbered by any lien and any amounts unencumbered by any lien) measured at the time associated with the triggering event. The amount of the single payment may be less than the amount of the cash payment.
摘要翻译：在房地产所有者和资本来源之间交换的金融工具。业主收到现金付款请求。现金支付由资本来源支付给业主。金融工具源于所有者到资本来源。现金支付金额等于金融工具发行时计量的财产价值的百分比。金融工具包括业主在与触发事件相关的时间向资本来源支付的义务，单笔付款金额等于房地产价值的百分比（包括由任何金额担保的任何金额）留置权和任何不受任何留置权限制的任何金额）在与触发事件相关的时间度量。单笔付款的金额可能少于现金支付金额。

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