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1. 发明申请

WO2009026588A2 SYSTEM FOR TRANSMITTING ELECTRICAL CURRENT TO A BODILY TISSUE 审中-公开
标题翻译：将电流传输到身体组织的系统
公开(公告)号：WO2009026588A2
公开(公告)日：2009-02-26
申请号：PCT/US2008/074252
申请日：2008-08-25
申请人： BIONESS INC. , GLUKHOVSKY, Arkady , WILKIN, Kevin , GORD, John , REGEV, Einan
发明人： GLUKHOVSKY, Arkady , WILKIN, Kevin , GORD, John , REGEV, Einan
IPC分类号： A61N1/36 , A61N1/02
CPC分类号： A61N1/36017 , A61N1/36021 , A61N1/3625 , A61N1/3756
摘要： In some embodiments, an apparatus includes a substrate, a power source, a connector, electrical circuitry, and an electrode assembly. The substrate has a first surface and a second surface different than the first surface. The power source has a positive terminal and a negative terminal Each of the positive terminal and the negative terminal are coupled to the substrate. The power source is configured to provide power to an external stimulator coupled to the apparatus. The connector is disposed proximate to the first surface of the substrate and is electrically coupled to at least one of the positive terminal and the negative terminal of the power source. The connector is configured to electrically couple the external stimulator to the power source. The electrical circuitry is coupled to the substrate. The electrical circuitry is configured to electrically couple the connector to at least one of the positive terminal and the negative terminal of the power source. At least one of the connector or the electrical circuitry is configured to prevent a short circuit of the electrical circuit. The electrode assembly is coupled to the second surface of the substrate. At least one electrode of the electrode assembly is configured to contact bodily tissue and to facilitate transmission of an electrical current through the bodily tissue.
摘要翻译：在一些实施例中，装置包括基板，电源，连接器，电路和电极组件。基板具有与第一表面不同的第一表面和第二表面。电源具有正极端子和负极端子正极端子和负极端子各自耦接到基板。电源被配置为向耦合到该设备的外部刺激器提供电力。连接器设置在基板的第一表面附近并且电耦合到电源的正极端子和负极端子中的至少一个。连接器被配置为将外部刺激器电耦合到电源。电路耦合到衬底。电路被配置为将连接器电耦合到电源的正极端子和负极端子中的至少一个。连接器或电路中的至少一个被配置为防止电路的短路。电极组件耦合到衬底的第二表面。电极组件的至少一个电极构造成接触身体组织并且促进电流通过身体组织的传播。

2. 发明申请

WO2011068849A1 SYSTEM FOR TRANSMITTING ELECTRICAL CURRENT TO A BODILY TISSUE 审中-公开
标题翻译：将电流传输到身体组织的系统
公开(公告)号：WO2011068849A1
公开(公告)日：2011-06-09
申请号：PCT/US2010/058525
申请日：2010-12-01
申请人： BIONESS INC. , DAR, Amit , FELDMAN, Shai , GLUKHOVSKY, Arkady , SPRINGER, Shmuel , REGEV, Einan
发明人： DAR, Amit , FELDMAN, Shai , GLUKHOVSKY, Arkady , SPRINGER, Shmuel , REGEV, Einan
IPC分类号： A61N1/00
CPC分类号： A61N1/36 , A61N1/04 , A61N1/0456 , A61N1/0472 , A61N1/048 , A61N1/0492 , A61N1/36017 , A61N1/36021 , A61N1/3625 , A61N1/375 , A61N1/3756 , A61N1/3758 , Y10T29/49826
摘要： In some embodiments, an apparatus includes a substantially rigid base and a flexible substrate. The substantially rigid base has a first protrusion and a second protrusion, and is configured to be coupled to an electronic device. The flexible substrate has a first surface and a second surface, and includes an electrical circuit configured to electronically couple the electronic device to at least one of an electrode a battery, or an antenna. The flexible substrate is coupled to the base such that a first portion of the second surface is in contact with the first protrusion. A second portion of the second surface is non-parallel to the first portion.
摘要翻译：在一些实施例中，装置包括基本上刚性的基部和柔性基底。基本上刚性的基座具有第一突起和第二突起，并且被配置为联接到电子设备。柔性基板具有第一表面和第二表面，并且包括被配置为将电子设备电连接到电极，电池或天线中的至少一个的电路。柔性基板与基座相连，使得第二表面的第一部分与第一突起接触。第二表面的第二部分不平行于第一部分。

3. 发明申请

WO2009158389A1 TREATMENT OF INDICATIONS USING ELECTRICAL STIMULATION 审中-公开
标题翻译：使用电刺激治疗适应症
公开(公告)号：WO2009158389A1
公开(公告)日：2009-12-30
申请号：PCT/US2009/048419
申请日：2009-06-24
申请人： BIONESS INC. , GLUKHOVSKY, Arkady , LINDON, Mark, L. , ZILBERMAN, Yitzhak
发明人： GLUKHOVSKY, Arkady , LINDON, Mark, L. , ZILBERMAN, Yitzhak
IPC分类号： A61N1/34
CPC分类号： A61N1/36007 , A61N1/375
摘要： In one embodiment, a method includes implanting an implant entirely under the subject's skin. The implant includes a passive electrical conductor of sufficient length to extend from subcutaneous tissue located below one of a surface cathodic electrode and a surface anodic electrode to the tibial nerve. The surface electrodes are positioned in spaced relationship on the subject's skin, with one of the electrodes positioned over the pick-up end of the electrical conductor such that the portion of the current is transmitted through the conductor to the tibial nerve, and such that the current flows through the tibial nerve and returns to the other of the surface cathodic electrode and the surface anodic electrode. An electrical current is applied between the surface cathodic electrode and the surface anodic electrode to cause the portion of the electrical current to flow through the implant to stimulate the tibial nerve.
摘要翻译：在一个实施例中，一种方法包括将植入物完全植入对象的皮肤下。植入物包括足够长度的无源电导体，其从位于表面阴极电极和表面阳极电极之下的皮下组织延伸到胫神经。表面电极以对等体的皮肤间隔开地定位，其中一个电极位于电导体的拾取端上方，使得电流的一部分通过导体传递到胫神经，并且使得电流流过胫神经并返回到另一个表面阴极电极和表面阳极。在表面阴极电极和表面阳极之间施加电流以使电流的一部分流过植入物以刺激胫神经。

4. 发明申请

WO2018152190A1 METHODS AND APPARATUS FOR BODY WEIGHT SUPPORT SYSTEM 审中-公开
公开(公告)号：WO2018152190A1
公开(公告)日：2018-08-23
申请号：PCT/US2018/018166
申请日：2018-02-14
申请人： BIONESS INC. , MCBRIDE, Keith , GLUKHOVSKY, Arkady , SMITH, Augustine
发明人： MCBRIDE, Keith , GLUKHOVSKY, Arkady , SMITH, Augustine
IPC分类号： A61H3/00 , A63B24/00 , A63B69/00
摘要： A body weight support system includes a tether configured to be coupled to an attachment device worn by a user to couple the user to the body weight support system. A method of providing gait training includes defining a reference length of the tether when the attachment device is in an initial position and defining a threshold length of the tether. A first amount of body weight support is provided during the gait training as the user moves relative to a surface and the length of the tether is less than the threshold length. A second amount of body weight support is provided during the gait training as the user moves relative to the surface and the length of the tether is greater than the threshold length. The method further includes displaying data associated with the gait training on a display of an electronic device.

5. 发明申请

WO2010017004A1 INSERTION TOOLS AND METHODS FOR AN ELECTRICAL STIMULATION IMPLANT 审中-公开
标题翻译：插入工具和电刺激植入物的方法
公开(公告)号：WO2010017004A1
公开(公告)日：2010-02-11
申请号：PCT/US2009/050648
申请日：2009-07-15
申请人： BIONESS INC. , GLUKHOVSKY, Arkady , ZILBERMAN, Yitzhak
发明人： GLUKHOVSKY, Arkady , ZILBERMAN, Yitzhak
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0551 , A61N1/08
摘要： In some embodiments, a method includes inserting at least a distal end portion of an insertion tool within a body. The distal end portion of the insertion tool is coupled to an electronic implant having a stimulation portion, a terminal portion and a substantially flexible conductor disposed between the stimulation portion and the terminal portion. The distal end portion of the insertion tool is moved within the body such that the stimulation portion of the electronic implant is disposed adjacent a target location and the terminal portion of the electronic implant is disposed beneath a skin of the body.
摘要翻译：在一些实施例中，一种方法包括将插入工具的至少前端部分插入体内。插入工具的远端部分连接到具有刺激部分，端子部分和布置在刺激部分和终端部分之间的基本上柔性的导体的电子植入物。插入工具的远端部分在主体内移动，使得电子植入物的刺激部分邻近目标位置设置，并且电子植入物的终端部分设置在身体的皮肤之下。

6. 发明申请

WO2009021157A1 APPARATUS AND METHODS FOR REMOVING AN ELECTRONIC IMPLANT FROM A BODY 审中-公开
标题翻译：从身体移除电子植入物的装置和方法
公开(公告)号：WO2009021157A1
公开(公告)日：2009-02-12
申请号：PCT/US2008/072557
申请日：2008-08-08
申请人： BIONESS INC. , ZILBERMAN, Yitzhak , CHAMBERLAIN, Mark , GLUKHOVSKY, Arkady
发明人： ZILBERMAN, Yitzhak , CHAMBERLAIN, Mark , GLUKHOVSKY, Arkady
IPC分类号： A61N1/36
CPC分类号： A61N1/372 , A61N1/3605 , A61N1/37205 , A61N1/375 , A61N1/3756
摘要： An apparatus includes an electronic stimulator configured to be implanted within a body, and a flexible member coupled to the electronic stimulator by an adhesive. In some embodiments, the flexible member is formulated to be soluble when exposed to a bodily tissue.
摘要翻译：一种装置包括被配置为植入体内的电子刺激器，以及通过粘合剂耦合到电子刺激器的柔性构件。在一些实施方案中，将柔性构件配制成当暴露于身体组织时是可溶的。

7. 发明申请

WO2009088563A1 METHODS AND APPARATUS FOR IMPLANTING ELECTRONIC IMPLANTS WITHIN THE BODY 审中-公开
标题翻译：用于在体内植入电子植入物的方法和装置
公开(公告)号：WO2009088563A1
公开(公告)日：2009-07-16
申请号：PCT/US2008/083084
申请日：2008-11-11
申请人： BIONESS INC. , GLUKHOVSKY, Arkady
发明人： GLUKHOVSKY, Arkady
IPC分类号： A61N1/04
CPC分类号： A61N1/05 , A61B17/3468 , A61B2017/00026 , A61B2017/00115 , A61B2017/0608 , A61B2017/3405 , A61B2017/3407 , A61B2017/3447 , A61B2090/062 , A61B2090/067 , A61N1/37205
摘要： Apparatus and methods for implanting electronic implants within the body are described herein. Such electronic implants can include, for example, elongated stimulating devices, sensors and/or electronic leads. In some embodiments, an apparatus includes a first member and a second member operatively coupled to the first member. The first member has a proximal end portion and a distal end portion. The distal end portion of the first member includes a target probe. The second member has a proximal end portion and a distal end portion. The distal end portion of the second member is configured to be selectively coupled to an electronic implant.
摘要翻译：本文描述了用于在体内植入电子植入物的装置和方法。这种电子植入物可以包括例如细长的刺激装置，传感器和/或电子引线。在一些实施例中，装置包括第一构件和可操作地联接到第一构件的第二构件。第一构件具有近端部分和远端部分。第一构件的远端部分包括靶探针。第二构件具有近端部分和远端部分。第二构件的远端部分构造成选择性地联接到电子植入物。

8. 发明申请

WO2007002741A1 IMPROVEMENTS TO AN IMPLANT, SYSTEM AND METHOD USING IMPLANTED PASSIVE CONDUCTORS FOR ROUTING ELECTRICAL CURRENT 审中-公开
标题翻译：使用嵌入式被动导线器进行电流的植入，系统和方法的改进
公开(公告)号：WO2007002741A1
公开(公告)日：2007-01-04
申请号：PCT/US2006/025146
申请日：2006-06-28
申请人： BIONESS DEVELOPMENT, LLC , GLUKHOVSKY, Arkady , ZILBERMAN, Yitzhak , PROCHAZKA, Arthur , CHAMBERLAIN, Mark , DAVIS, Ross , SCHULMAN, Joseph
发明人： GLUKHOVSKY, Arkady , ZILBERMAN, Yitzhak , PROCHAZKA, Arthur , CHAMBERLAIN, Mark , DAVIS, Ross , SCHULMAN, Joseph
IPC分类号： A61N1/34 , A61N1/05
CPC分类号： A61N1/05 , A61N1/0456 , A61N1/0551 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： The present invention provides improvements to an implant, system and method using passive electrical conductors which route electrical current to either external or implanted electrical devices, to multiple target body tissues and to selective target body tissues. The passive electrical conductor extends from subcutaneous tissue located below either a surface cathodic electrode or a surface anodic electrode a) to a target tissue to route electrical signals from the target body tissue to devices external to the body; b) to implanted electrical devices to deliver electrical current to such devices, or c) to multiple target body tissues or to selective target body tissues to stimulate the target body tissues. The conductor has specialized ends for achieving such purposes.
摘要翻译：本发明提供对使用无源电导体的植入物，系统和方法的改进，所述无源电导体将电流路由到外部或植入的电气装置，多个靶体组织和选择性靶体组织。无源电导体从位于表面阴极电极或表面阳极电极a）下方的皮下组织延伸到目标组织，以将电信号从目标体组织转移到身体外部的装置; b）植入电气装置以将电流传送到这种装置，或c）到多个靶体组织或选择性靶组织以刺激靶体组织。导体具有实现此目的的专门目的。

9. 发明申请

WO2002102223A2 MOTILITY ANALYSIS WITHIN A GASTROINTESTINAL TRACT 审中-公开
标题翻译：动力学分析在气体分析中的应用
公开(公告)号：WO2002102223A2
公开(公告)日：2002-12-27
申请号：PCT/IL2002/000386
申请日：2002-05-19
申请人： GIVEN IMAGING LTD. , GLUKHOVSKY, Arkady , MERON, Gavriel , ZINATI, Ofra
发明人： GLUKHOVSKY, Arkady , MERON, Gavriel , ZINATI, Ofra
IPC分类号： A61B
CPC分类号： A61B1/041 , A61B1/042 , G06F19/00
摘要： A system and method for measuring and analyzing motility within a body lumen such as the gastrointestinal (GI) tract, where an in vivo imaging device such as a capsule captures images and transmits the images to a processor, which calculates the motility of the device based on comparison of the images. Preferably, the processor compares the intensity of pairs of images or of elements of pairs of images, generates a variance for the compared images, and calculates the motility of the imaging device from the variances. The motility data may be presented to a user in various manners; for example, a plot of motility over time may be generated, or indications of low motility may be presented to the user of the system.
摘要翻译：一种用于测量和分析诸如胃肠（GI）管道的体腔内的运动性的系统和方法，其中诸如胶囊的体内成像装置捕获图像并将图像发送到处理器，该处理器计算基于装置的运动性比较图像。优选地，处理器比较图像对或图像对的元素的强度，为比较的图像生成方差，并根据方差计算成像装置的运动性。运动数据可以以各种方式呈现给用户; 例如，可以产生随时间的运动性图，或者可以向系统的用户呈现低运动性的指示。

10. 发明申请

WO2002094337A3 A METHOD FOR IN VIVO IMAGING OF AN UNMODIFIED GASTROINTESTINAL TRACT 审中-公开
公开(公告)号：WO2002094337A3
公开(公告)日：2002-11-28
申请号：PCT/IL2002/000391
申请日：2002-05-20
申请人： GIVEN IMAGING LTD. , GLUKHOVSKY, Arkady
发明人： GLUKHOVSKY, Arkady
IPC分类号： A61B6/00
摘要： Imaging device (40) which is capable for insertion in the intestine has a convex shaped tip (402) of endoscope (400) with an optical window (42) through which the intestine is illuminated, viewed and/or imaged.

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