专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2008102932A1 COMPOSITIONS FOR TREATING HYPERPROLIFERATIVE VASCULAR DISORDERS AND CANCERS 审中-公开
标题翻译：用于治疗高血压性血管疾病和癌症的组合物
公开(公告)号：WO2008102932A1
公开(公告)日：2008-08-28
申请号：PCT/KR2007/002512
申请日：2007-05-23
申请人： BIOBUD CO., LTD. , CHUNG, Kwang Hoe , PAK, Chwang Siek , HONG, Sung Yu , KANG, Soo Jung , SOHN, Young Doug , HWANG, Jae Hoon , CHOI, Eun Bok , YON, Gyu Hwan , LEE, Hyeon-Kyu , YANG, Heui Cheol
发明人： CHUNG, Kwang Hoe , PAK, Chwang Siek , HONG, Sung Yu , KANG, Soo Jung , SOHN, Young Doug , HWANG, Jae Hoon , CHOI, Eun Bok , YON, Gyu Hwan , LEE, Hyeon-Kyu , YANG, Heui Cheol
IPC分类号： A61K31/47
CPC分类号： A61K31/47
摘要： The present invention relates to a pharmaceutical composition for preventing or treating hyperproliferative vascular disorders, and a pharmaceutical anticancer composition comprising the compound represented by the Formula 1. The present compounds exhibit IC 50 values of less than 0.16 μM for vascular smooth muscle cells and cancer cells to effectively prevent proliferation of vascular smooth muscle cells and cancer cells, thereby ensuring prevention or treatment of hyperproliferative vascular disorders such as arteriosclerosis and restenosis, and cancers.
摘要翻译：本发明涉及用于预防或治疗过度增殖性血管疾病的药物组合物，以及含有式1表示的化合物的药物抗癌组合物。本发明化合物的IC 50值小于0.16μM，血管平滑肌细胞和癌细胞，以有效地防止血管平滑肌细胞和癌细胞的增殖，从而确保预防或治疗过度增生性血管疾病如动脉硬化和再狭窄以及癌症。

2. 发明申请

WO2009084841A2 MUTATED NUCLEOTIDE SEQUENCES OF BATROXOBIN, MUTATED ALPHA FACTOR SECRETION SIGNAL SEQUENCE AND PROCESSES FOR PREPARING BATROXOBIN USING THE SAME 审中-公开
标题翻译：巴豆红素的突变核苷酸序列，突变的ALPHA因子分泌信号序列和使用其制备巴豆红素的方法
公开(公告)号：WO2009084841A2
公开(公告)日：2009-07-09
申请号：PCT/KR2008/007605
申请日：2008-12-23
申请人： BIOBUD CO., LTD. , SOHN, Young-Doug , KIM, Bum Joon , KIM, Ok Hwan , KIM, Kyoung Jun , SHIN, Ji Hun , HONG, Sung Yu , HWANG, Jae Hoon , CHUNG, Kwang Hoe
发明人： SOHN, Young-Doug , KIM, Bum Joon , KIM, Ok Hwan , KIM, Kyoung Jun , SHIN, Ji Hun , HONG, Sung Yu , HWANG, Jae Hoon , CHUNG, Kwang Hoe
IPC分类号： C12N9/64
CPC分类号： C12N9/6418 , C07K2319/02
摘要： The present invention relates to a batroxobin-encoding nucleotide sequence and/or a mutated α-factor secretion signal sequence, and a vector and a transformant using the same. The batroxobin-encoding nucleotide sequence of this invention exhibits an excellent expression efficiency in yeast, particular Pichia pastoris and the recombinant batroxobin is obtained at 4-13 fold higher yield than natural-occurring batroxobin-encoding sequences. The protein expression system which uses the batroxobin-encoding nucleotide sequence as well as mutated α-factor secretion signal peptide sequence of this invention obtains the recombinant batroxobin at about 20-fold higher yield than natural-occurring batroxobin-encoding sequences. In addition, the recombinant batroxobin prepared using the sequence of this invention has a significantly plausible activity and stability compared with natural-occuring batroxobin.
摘要翻译：本发明涉及一种编码巴曲酶的核苷酸序列和/或突变的a因子分泌信号序列，以及使用该序列的载体和转化体。本发明的巴曲酶编码核苷酸序列在酵母，特别是巴斯德毕赤酵母中表现出优异的表达效率，并且以比天然存在的巴曲酶编码序列高出4-13倍的产量获得重组巴曲酶。使用巴曲酶编码核苷酸序列以及本发明的突变型a因子分泌信号肽序列的蛋白质表达系统获得比天然存在的巴曲酶编码序列高约20倍的重组巴曲酶。此外，使用本发明的顺序制备的重组巴曲酶与天然发生的巴曲酶相比具有显着似乎合理的活性和稳定性。

3. 发明申请

WO2010010978A1 NOX SENSOR 审中-公开
标题翻译： NOX传感器
公开(公告)号：WO2010010978A1
公开(公告)日：2010-01-28
申请号：PCT/KR2008/004296
申请日：2008-07-23
申请人： CIOS INC. , PARK, Jinsu , HWANG, Jae Hoon
发明人： PARK, Jinsu , HWANG, Jae Hoon
IPC分类号： G01N27/407 , G01N27/12
CPC分类号： G01N27/4075 , G01N27/419
摘要： Disclosed is a NOx sensor which gives an output of the same direction with respect to NO and NO2 with the same sensitivity, thereby precisely measuring total NOx concentration, and also which can be reacted with only NO2 according to a forming method of an oxide sensing electrode. The NOx sensor comprises an oxygen ion conductive solid electrolyte 10; one or more oxide sensing electrodes 20 formed at the oxygen ion conductive solid electrolyte 10; a first noble metal electrode 30 formed at the oxide sensing electrode 20; a second noble metal electrode 40 formed at the oxygen ion conductive solid electrolyte 10; and an electromotive force lead line 50 for the electrical connection of the oxide sensing electrode 20 and the second noble metal electrode 40. The oxide sensing electrode 20 and the second noble metal electrode 40 are connected in parallel to each other through the first metal electrode 30.
摘要翻译：公开了一种NOx传感器，其以相同的灵敏度给出与NO和NO2相同方向的输出，从而精确测量总NOx浓度，并且还可以根据氧化物感测电极的形成方法仅与NO 2反应。 NOx传感器包括氧离子导电固体电解质10; 形成在氧离子传导性固体电解质10上的一个或多个氧化物检测电极20; 形成在氧化物感测电极20上的第一贵金属电极30; 在氧离子导电固体电解质10上形成的第二贵金属电极40; 以及用于氧化物检测电极20和第二贵金属电极40的电连接的电动势引线50.氧化物感测电极20和第二贵金属电极40通过第一金属电极30彼此并联连接。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式