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1. 发明申请

WO2014151596A2 SYSTEM AND METHOD FOR INHOMOGENEOUS MAGNETIZATION TRANSFER MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：非均匀磁化传输磁共振成像系统与方法
公开(公告)号：WO2014151596A2
公开(公告)日：2014-09-25
申请号：PCT/US2014/026077
申请日：2014-03-13
申请人： BETH ISRAEL DEACONESS MEDICAL CENTER , ALSOP, David , VARMA, Gopal
发明人： ALSOP, David , VARMA, Gopal
IPC分类号： A61B5/055
CPC分类号： G01R33/5605 , A61B5/055 , A61B5/4041 , A61B5/7278 , G01R33/4828 , G01R33/50 , G01R33/5659
摘要： A system and method for producing a report about a subject from data collected from the subject using a magnetic resonance imaging (MRI] system. The method includes directing the MRI system to perform a pulse sequence to manipulate exchangeable magnetization in the subject and acquiring, with the MRI system, imaging data from the subject in response to the pulse sequence. The method also includes analyzing the effects of the frequencies of applied RF energy on the imaging data to identify inhomogeneous lines formed by a summation of multiple sublines centered at multiple different frequencies. The method further includes generating a report pertaining to inhomogeneous magnetization transfer occurring in the subject in response to the pulse sequence.
摘要翻译：一种用于使用磁共振成像（MRI）系统从从受试者收集的数据产生关于受试者的报告的系统和方法，所述方法包括指导MRI系统执行脉冲序列以操纵受试者的可交换磁化，并以 MRI系统，响应于脉冲序列成像来自受试者的数据，该方法还包括分析所施加的RF能量的频率对成像数据的影响，以识别由以多个不同频率为中心的多个子集的求和形成的不均匀线该方法还包括响应于脉冲序列产生关于受试者中发生的非均匀磁化转移的报告。

2. 发明申请

WO2017124089A1 SYSTEM AND METHOD FOR IMPROVED HOMOGENEOUS AND INHOMOGENEOUS MAGNETIZATION TRANSFER MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：改进的均匀和不均匀磁化转移磁共振成像的系统和方法
公开(公告)号：WO2017124089A1
公开(公告)日：2017-07-20
申请号：PCT/US2017/013760
申请日：2017-01-17
申请人： BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
发明人： ALSOP, David , VARMA, Gopal
IPC分类号： G01R33/561 , A61B5/055 , G01R33/32 , G01R33/421 , G01R33/385 , G01R33/38
CPC分类号： G01R33/5605
摘要： A system and methods for improved homogeneous and inhomegeneous magnetic transfer imaging are provided. In some aspects, a plurality of gradient coils and an RF system of a magnetic resonance imaging ("MRI") system are controlled, using a computer, to perform, at least one pulse sequence that includes a preparation module followed by an imaging module, wherein the preparation module comprises a plurality of radio frequency ("RF") saturation pulses applied according to a concentrated pulse cycle to manipulate exchangeable magnetization from protons in the subject, and the imaging module is configured to acquire image data. The computer is also configured to analyze the image data acquired to generate frequency information indicative of the exchangeable magnetization from protons in the subject, and generate a report, using the frequency information, pertaining to inhomogeneous or homogeneous magnetization transfer occurring in the subject.
摘要翻译：提供了用于改善均匀和不均匀磁传递成像的系统和方法。在一些方面，使用计算机来控制磁共振成像（“MRI”）系统的多个梯度线圈和RF系统以执行至少一个脉冲序列，该脉冲序列包括准备模块，随后是成像模块，其中所述准备模块包括根据集中脉冲周期施加的多个射频（“RF”）饱和脉冲，以操纵来自所述对象中的质子的可交换磁化，并且所述成像模块被配置为获取图像数据。该计算机还被配置为分析获取的图像数据以生成指示来自受试者中的质子的可交换磁化的频率信息，并且使用关于发生在受试者中的不均匀或均匀磁化转移的频率信息生成报告。 p>

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