专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010000409A3 COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS 审中-公开
标题翻译：用于生产放射性药物的化合物和工艺
公开(公告)号：WO2010000409A3
公开(公告)日：2010-03-04
申请号：PCT/EP2009004537
申请日：2009-06-24
申请人： BAYER SCHERING PHARMA AG , SRINIVASAN ANANTH , BERNDT MATHIAS , GRAHAM KEITH , FRIEBE MATTHIAS , SCHMITT-WILLICH HERIBERT
发明人： SRINIVASAN ANANTH , BERNDT MATHIAS , GRAHAM KEITH , FRIEBE MATTHIAS , SCHMITT-WILLICH HERIBERT
IPC分类号： C07B59/00 , C07C309/65 , C07C309/73 , C07C309/80 , C07C309/86
CPC分类号： C07B59/00 , C07B2200/05 , C07C309/65 , C07C309/73
摘要： The present invention relates to novel perfluorinated precursors for the production of F- 18 labeled radiotracers for Positron Emission Tomography (PET) and processes for radiolabeling and purification using these precursors. The invention also comprises radiopharmaceutical kits using these precursors and processes.
摘要翻译：本发明涉及用于生产用于正电子发射断层扫描术（PET）的F-18标记的放射性示踪剂的新型全氟化前体和使用这些前体进行放射性标记和纯化的方法。本发明还包括使用这些前体和过程的放射性药物试剂盒。

2. 发明申请

WO2008028688A3 COMPOUNDS AND METHODS FOR 18F LABELED AGENTS 审中-公开
标题翻译： 18F标记药物的化合物和方法
公开(公告)号：WO2008028688A3
公开(公告)日：2008-11-13
申请号：PCT/EP2007008042
申请日：2007-09-07
申请人： BAYER SCHERING PHARMA AG , LEHMANN LUTZ , SRINIVASAN ANANTH , BRUMBY THOMAS , SUELZLE DETLEF , STELLFELD TIMO , GRAHAM KEITH , KARRAMKAM MYLENE , AMETAMEY SIMON
发明人： LEHMANN LUTZ , SRINIVASAN ANANTH , BRUMBY THOMAS , SUELZLE DETLEF , STELLFELD TIMO , GRAHAM KEITH , KARRAMKAM MYLENE , AMETAMEY SIMON
IPC分类号： A61K51/08 , A61K51/04 , C07C255/58 , C07K7/06
CPC分类号： C07K7/086 , A61K51/0491 , A61K51/088 , C07B59/00 , C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07K1/13 , C07K14/57545 , C07K14/6555
摘要： The present invention relates to novel compounds suitable for or already radiolabeled with 18 F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled compounds are characterized by Formula II, wherein the substituents G, Q, L, Y and U have the meaning as defined in the specification and claims.
摘要翻译：本发明涉及适用于或已经用18 F放射性标记的新颖化合物，制备此类化合物的方法以及这些化合物用于诊断成像的用途。此类标记的化合物由式II表征，其中取代基G，Q，L，Y和U具有如说明书和权利要求书中所定义的含义。

3. 发明申请

WO2008104203A2 RADIO FLUORIDATION METHODS 审中-公开
标题翻译：无线荧光法
公开(公告)号：WO2008104203A2
公开(公告)日：2008-09-04
申请号：PCT/EP2007007967
申请日：2007-09-07
申请人： BAYER SCHERING PHARMA AG , SRINIVASAN ANANTH , STELLFELD TIMO
发明人： SRINIVASAN ANANTH , STELLFELD TIMO
IPC分类号： A61K49/04 , A61K31/7072 , A61K38/08 , A61K49/08 , A61K49/10 , A61K51/04 , C07D249/18 , C07D405/04 , C07D405/14 , C07D409/04 , C07K1/13 , C07K5/02 , C07K5/023 , C07K7/06
CPC分类号： C07D249/18 , A61K38/00 , A61K49/085 , A61K49/14 , A61K51/088 , C07D233/64 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D471/04 , C07K1/13 , C07K5/0202 , C07K5/0205 , C07K7/086 , C07K14/655
摘要： The present invention relates to radiolabeled substitute benzene compounds for diagnostic imaging. The present invention provides methods for preparation of such compounds, in particular, preparation of novel compounds which serve as precursors for 18 F-labeling, and the use of thus 18 F-labeled compounds for diagnostic imaging.
摘要翻译：本发明涉及用于诊断成像的放射性标记的替代苯化合物。本发明提供了这样的化合物的制备方法，特别是制备用作 F-F标记的前体的新化合物，以及使用这样的“ 标记的化合物用于诊断成像。

4. 发明申请

WO2008040441A2 RADIOFLUORINATION 审中-公开
标题翻译：放射性氟化
公开(公告)号：WO2008040441A2
公开(公告)日：2008-04-10
申请号：PCT/EP2007008044
申请日：2007-09-07
申请人： BAYER SCHERING PHARMA AG , SRINIVASAN ANANTH , LEHMANN LUTZ , VOIGTMANN ULRIKE , STELLFELD TIMO , AMETAMEY SIMON , KLAR ULRICH , HOEHNE AILEEN , MU LINJING
发明人： SRINIVASAN ANANTH , LEHMANN LUTZ , VOIGTMANN ULRIKE , STELLFELD TIMO , AMETAMEY SIMON , KLAR ULRICH , HOEHNE AILEEN , MU LINJING
IPC分类号： A61K31/695 , A61K51/04 , A61K51/08 , C07F7/02 , C07K1/13
CPC分类号： C07K1/13 , A61K49/085 , A61K49/10 , A61K49/14 , A61K51/0491 , C07B59/004 , C07B59/008 , C07F7/0834 , C07F7/0896 , C07F7/12 , C07K7/02 , C07K7/086
摘要： The present invention relates to novel compounds suitable for or already radiolabeled with 18 F, methods of making such compounds and use of such compounds for diagnostic imaging. Such labeled vompounds are characerized by Formula II, wherein the moieties F, R 1 , R 2 , B 1,2, Y 1.2 ,, Z 1.2
摘要翻译：本发明涉及适用于或已经用<！ - SIPO - >已经放射性标记的新化合物，制备这些化合物的方法和用于诊断成像的这些化合物的用途。这种标记的化合物通过式II化合，其中部分F，R 1，R 2，B，1,2， 1.2，Z <1.2>

5. 发明申请

WO2008046493A3 RADIOACTIVE METAL COMPLEXES COMPRISING A TRIDENTATE COMPLEXING SEQUENCE 审中-公开
标题翻译：包含三元复合序列的放射性金属复合物
公开(公告)号：WO2008046493A3
公开(公告)日：2008-06-05
申请号：PCT/EP2007008334
申请日：2007-09-25
申请人： CIS BIO INT , CYR JOHN , DUATTI ADRIANO , UCCELLI LICIA , BOSCHI ALESSANDRA , SRINIVASAN ANANTH , PASQUALINI ROBERTO
发明人： CYR JOHN , DUATTI ADRIANO , UCCELLI LICIA , BOSCHI ALESSANDRA , SRINIVASAN ANANTH , PASQUALINI ROBERTO
IPC分类号： C07F13/00 , A61K51/08 , A61K51/10
CPC分类号： C07F13/005 , A61K51/088
摘要： The present invention relates to a metal complex of the general formula MX n (Q)L m , wherein M is a transition metal ion; X is nitrido or oxo; Q is a tridentate ligand comprising a peptide P, wherein P contains from 1 to 20 amino acids and optionally complexing moieties and includes a tridentate complexing sequence AB comprising at least three metal complexing donor atoms, wherein A and B are independently an amino acid or a complexing moiety and are linked by an amide bond, wherein the metal complexing donor atoms of AB consist of either two sulfur atoms and one nitrogen atom, or one sulfur atom and two nitrogen atoms in a sequence selected from SNS, SNN, and NNS, wherein the central nitrogen in the sequence SNS, SNN, and NNS is an amide bond nitrogen; L is a co-ligand selected from the group consisting of phosphine, thiol, arsine, carbonyl, and halide ligand; n is 0 or 1 and m = 1 or 3, with the proviso that when n = 0, m = 3, and that when n = 1, m = 1.
摘要翻译：本发明涉及通式为MX（Q）L m的金属络合物，其中M为过渡金属离子; X是硝基或氧代; Q是包含肽P的三齿配体，其中P含有1至20个氨基酸和任选的络合部分，并且包括包含至少三个金属络合供体原子的三齿络合序列AB，其中A和B独立地是氨基酸或络合部分并通过酰胺键连接，其中AB的金属络合供体原子由选自SNS，SNN和NNS的序列中的两个硫原子和一个氮原子，或一个硫原子和两个氮原子组成，其中序列SNS，SNN和NNS中的中心氮是酰胺键氮; L是选自磷化氢，硫醇，胂，羰基和卤化物配体的共配位体; n为0或1，m = 1或3，条件是当n = 0时，m = 3，当n = 1时，m = 1。

6. 发明申请

WO2012129029A3 MULTIPLE LINER HANGER ASSEMBLY 审中-公开
标题翻译：多头衬里吊架总成
公开(公告)号：WO2012129029A3
公开(公告)日：2012-11-22
申请号：PCT/US2012029075
申请日：2012-03-14
申请人： BAKER HUGHES INC , SRINIVASAN ANANTH , HARRIS ALEX D , TALBOT TODD J
发明人： SRINIVASAN ANANTH , HARRIS ALEX D , TALBOT TODD J
IPC分类号： E21B43/08 , E21B11/02 , E21B23/00
CPC分类号： E21B23/01 , E21B7/20 , E21B43/10
摘要： A hanger assembly provided for multiple hanging opportunities. If liner is being run and the primary hanger doesn't work then a backup hanger is available to set near the nonfunctional primary hanger. In drilling with casing applications when there is a steering equipment malfunction or an MWD breakdown or bit wear requiring the BHA to be pulled, the liner can be hung where it is and the BHA pulled. Upon running back in with the BHA on a running tool the initial hanger can be released and the running tool configured to only set a different hanger when the total depth is reached in drilling with the liner. The running tool is then retrieved and the completion can go on.
摘要翻译：为悬挂机会提供悬挂装置。如果班轮正在运行且主衣架不起作用，则可以在非功能主衣架附近设置备用衣架。在出现转向设备故障或MWD故障或需要拉动BHA的钻头磨损情况下进行套管应用钻孔时，可将衬管悬挂在其所在位置并将BHA拉出。在BHA运行的工具上运行时，初始吊架可以被释放，并且运行工具被配置为在与衬管一起钻入总深度时仅设置不同的吊架。然后检索正在运行的工具，完成可以继续。

7. 发明申请

WO2012129029A2 MULTIPLE LINER HANGER ASSEMBLY 审中-公开
标题翻译：多个内胆组件
公开(公告)号：WO2012129029A2
公开(公告)日：2012-09-27
申请号：PCT/US2012029075
申请日：2012-03-14
申请人： BAKER HUGHES INC , SRINIVASAN ANANTH , HARRIS ALEX D , TALBOT TODD J
发明人： SRINIVASAN ANANTH , HARRIS ALEX D , TALBOT TODD J
IPC分类号： E21B43/08 , E21B11/02 , E21B23/00
CPC分类号： E21B23/01 , E21B7/20 , E21B43/10
摘要： A hanger assembly provided for multiple hanging opportunities. If liner is being run and the primary hanger doesn't work then a backup hanger is available to set near the nonfunctional primary hanger. In drilling with casing applications when there is a steering equipment malfunction or an MWD breakdown or bit wear requiring the BHA to be pulled, the liner can be hung where it is and the BHA pulled. Upon running back in with the BHA on a running tool the initial hanger can be released and the running tool configured to only set a different hanger when the total depth is reached in drilling with the liner. The running tool is then retrieved and the completion can go on.
摘要翻译：提供多个悬挂机会的衣架组合。如果衬管正在运行，并且主衣架不起作用，则备用衣架可用于设置在非功能性主吊架附近。在有套管应用的情况下，当有转向设备故障或MWD故障或钻头磨损要求BHA被拉动时，衬管可以挂在其上并且BHA拉。在运行工具上返回BHA时，可以释放初始衣架，并且运行工具配置为仅在使用衬管钻孔时达到总深度时才设置不同的衣架。然后检索运行的工具，完成可以继续。

8. 发明申请

WO2007039318A3 NEUROPEPTIDE Y ANALOGS 审中-公开
标题翻译：神经元Y模拟
公开(公告)号：WO2007039318A3
公开(公告)日：2007-07-05
申请号：PCT/EP2006009812
申请日：2006-10-05
申请人： SCHERING AG , SRINIVASAN ANANTH
发明人： SRINIVASAN ANANTH
IPC分类号： C07K14/575 , A61K38/22 , G01N33/68
CPC分类号： C07K14/57545
摘要： The neuropeptideY (NPY) -receptor-subtype Yl is expressed differentially from breast tumor cells and is therefore an advantageous target molecule for the molecular imaging of breast cancer. Peptide analogs were synthesized, whose sequence is reduced to the receptor-binding sections of the natural ligand NPY. These Yl receptor-selective peptide analogs contain unnatural amino acids that increase the receptor affinity and are to ensure the stability of the greatly shortened peptide. New NPY analogs, which are to be used as radioligands, were tested for their binding affinity and selectivity for the Yl receptor.
摘要翻译：神经肽Y（NPY）受体亚型Y1与乳腺肿瘤细胞差异表达，因此是乳腺癌分子成像的有利靶分子。合成肽类似物，其序列被还原成天然配体NPY的受体结合部分。这些Y1受体选择性肽类似物含有增加受体亲和力的非天然氨基酸，并且确保大大缩短的肽的稳定性。测试用作放射性配体的新NPY类似物对Y1受体的结合亲和力和选择性。

9. 发明申请

WO2006114323A2 ORTHOGONALLY PROTECTED BIFUNCTIONAL AMINO ACID 审中-公开
标题翻译：正交保护的双官能氨基酸
公开(公告)号：WO2006114323A2
公开(公告)日：2006-11-02
申请号：PCT/EP2006003993
申请日：2006-04-28
申请人： SCHERING AG , SRINIVASAN ANANTH , LUYT LEONARD G
发明人： SRINIVASAN ANANTH , LUYT LEONARD G
IPC分类号： C07C217/22 , C07C269/04 , C07C269/06 , C07K7/06 , C07K7/52
CPC分类号： C07K14/6555 , C07C323/59 , C07C2603/18
摘要： The present invention concerns novel orthogonally protected amino acids, there production and use for the synthesis of binding Compounds usable in the diagnosis and treatment of proliferative diseases, in particular tumor diseases.
摘要翻译：本发明涉及新颖的正交保护的氨基酸，其中生产和用于合成结合的化合物可用于诊断和治疗增殖性疾病，特别是肿瘤疾病的化合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式