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    • 4. 发明申请
    • AN INTRAOCULAR LENS INCORPORATING A UV - ABSORBING BENZOTRIAZOLE
    • 含有紫外吸收苯并噻唑的内窥镜
    • WO2011071673A1
    • 2011-06-16
    • PCT/US2010/057323
    • 2010-11-19
    • BAUSCH & LOMB INCORPORATEDVANDERBILT, David, Paul
    • VANDERBILT, David, Paul
    • G02B1/04A61F2/16C07D249/20
    • A61F2/16A61F2/1613A61F2002/1681A61F2002/16965C07D249/20G02B1/043
    • An intraocular lens comprising:(a) monomeric units derived from at least one cationically polymerizable branched alkene monomer;(b) monomeric units derived from at least one cationically polymerizable monomer having a pendant benzocyclobutene group; and (c) a UV-absorbing benzotriazole component having the formula (I) wherein R 1 and R 2 are independently selected from hydrogen, methyl, ethyl, propyl, iso-propyl, a C 4 -C 10 branched alkyl with one or two optional ether linkages, C 2 -C 16 alkylene with one or two optional ether or aromatic linkages and -NHCOR 4 , wherein R 4 is a C 4 -C 10 branched alkyl with one or two optional ether linkages or C 2 -C 16 alkylene with one or two optional ether or aromatic linkages, and at least one of R 1 , R 2 and R 4 is a C 2 -C 16 alkylene with one or two optional ether or aromatic linkages; and R 3 is hydrogen, -OCH 3 , -OC 2 H 5 , fluoro, chloro, bromo or iodo.
    • 一种眼内透镜,其包含:(a)衍生自至少一种阳离子可聚合支化烯烃单体的单体单元;(b)衍生自至少一种具有侧链苯并环丁烯基的阳离子聚合单体的单体单元; 和(c)具有式(I)的UV吸收苯并三唑组分,其中R 1和R 2独立地选自氢,甲基,乙基,丙基,异丙基,具有一个或两个任选的醚键的C 4 -C 10支链烷基, C 2 -C 16亚烷基与一个或两个任选的醚或芳族键和-NHCOR 4,其中R 4是具有一个或两个任选的醚键的C 4 -C 10支链烷基或具有一个或两个任选的醚或芳族键的C 2 -C 16亚烷基, R 1,R 2和R 4中的至少一个是具有一个或两个任选的醚或芳族键的C 2 -C 16亚烷基; 和R 3为氢,-OCH 3,-OC 2 H 5,氟,氯,溴或碘。