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1. 发明申请

WO0172356A2 STOPPERING METHOD TO MAINTAIN STERILITY 审中-公开
标题翻译：停止方法维持不变性
公开(公告)号：WO0172356A2
公开(公告)日：2001-10-04
申请号：PCT/US0109778
申请日：2001-03-27
申请人： ATRIX LAB INC
发明人： YARBOROUGH CODY L , DUNCAN MICHAEL R , NORTON RICHARD L , BAWA RAJAN , MADRIL DOMINIC G , BARRETT CHRISTOPHER J
IPC分类号： A61M5/28 , A61M5/31 , A61M5/315 , A61M5/00
CPC分类号： A61M5/31511 , A61M5/284 , A61M5/3137 , A61M2005/3104 , A61M2005/3121 , A61M2005/3139
摘要： A syringe assembly is provided which includes a hollow barrel that has an interior wall. The interior wall defines a chamber that retains medication. The hollow barrel also includes a distal end and a proximal end. The distal end of the hollow barrel has a passageway that is in contact with the chamber. The proximal end of the hollow barrel has an aperture. The syringe assembly also includes a primary plunger tip that is slidably positioned, in fluid tight engagement, with the interior wall. The primary plunger tip has a receptor to engage an engager of an elongated tip removal rod. The syringe assembly also includes a secondary plunger tip that is slidably positioned, in fluid tight engagement, with the interior wall. The secondary plunger tip also has a receptor to engage an engager of a tip removal rod. The secondary plunger tip is disposed between the primary plunger tip and the proximal end of the hollow barrel. The syringe assembly also includes a tip removal rod, which facilitates operation of the secondary plunger tip, engaged to the secondary plunger tip. The present invention also provides a process for providing a lyophilized medication (i.e., lyophilized) in a syringe assembly and also provides a process for reconstituting a medication in a syringe assembly.
摘要翻译：提供了一种注射器组件，其包括具有内壁的中空筒体。内壁限定了保留药物的室。中空筒还包括远端和近端。中空筒的远端具有与腔接触的通道。中空筒的近端具有孔。注射器组件还包括与内壁以可流体紧密接合的方式可滑动地定位的主柱塞尖端。主柱塞头具有接合器以接合细长尖端移除杆的接合部。注射器组件还包括与内壁以可流体紧密接合的方式可滑动地定位的次级柱塞末端。次级柱塞尖端还具有接合器以接合尖端移除杆的接合器。次级柱塞头设置在主柱塞尖端和中空筒的近端之间。注射器组件还包括尖端移除杆，其有助于辅助柱塞尖端的操作，接合到次级柱塞尖端。本发明还提供了一种在注射器组件中提供冻干药物（即，冻干的）的方法，并且还提供了用于在注射器组件中重建药物的方法。

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