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1. 发明申请

WO2012178119A3 TISSUE EXTRACTION DEVICES AND METHODS 审中-公开
标题翻译：组织提取装置和方法
公开(公告)号：WO2012178119A3
公开(公告)日：2013-04-04
申请号：PCT/US2012043891
申请日：2012-06-22
申请人： ARQOS SURGICAL INC , GERMAIN AARON , KLEIN KYLE , ORCZY-TIMKO BENEDEK , WALKER MICHAEL D , SHADDUCK JOHN H , TRUCKAI CSABA , LESKO BALAZS
发明人： GERMAIN AARON , KLEIN KYLE , ORCZY-TIMKO BENEDEK , WALKER MICHAEL D , SHADDUCK JOHN H , TRUCKAI CSABA , LESKO BALAZS
IPC分类号： A61B17/32
CPC分类号： A61B18/1485 , A61B17/32002 , A61B18/1482 , A61B18/18 , A61B2017/320028 , A61B2018/00083 , A61B2018/00196 , A61B2018/00559 , A61B2018/00601 , A61B2018/00982 , A61B2018/142 , A61B2218/002 , A61B2218/007
摘要： The tissue cutting device comprises an elongated assembly including both an outer sleeve and an inner sleeve. The outer sleeve has a tissue-receiving window, and the inner sleeve has a distal end which cuts tissue as the inner sleeve is advanced past the window. The tissue is received into a lumen of the inner sleeve, and the inner sleeve lumen is typically enlarged in a proximal direction to reduce the tendency of resected tissue to lodge therein. The tissue displacement member is optionally provided at a distal end of the outer sleeve to further aid in dislodging tissue which becomes captured in a distal end of the inner sleeve of the lumen.
摘要翻译：组织切割装置包括包括外套筒和内套筒的细长组件。外套筒具有组织接收窗口，并且内套筒具有远端，当内套筒推进通过窗口时，其切断组织。组织被容纳到内套筒的内腔中，并且内套筒腔通常在近端方向上增大，以减少切除的组织在其中的倾向。组织移位构件任选地设置在外套筒的远端处，以进一步有助于移除在管腔的内套筒的远端中被捕获的组织。

2. 发明申请

WO2012018545A3 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠呼吸暂停的系统和方法
公开(公告)号：WO2012018545A3
公开(公告)日：2012-05-03
申请号：PCT/US2011044880
申请日：2011-07-21
申请人： REVENT MEDICAL INC , GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA , POUTIATINE ANDREW , BUSCEMI PAUL J
发明人： GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA , POUTIATINE ANDREW , BUSCEMI PAUL J
IPC分类号： A61F5/56 , A61F2/02
CPC分类号： A61F5/566
摘要： A method of treating an airway disorder includes placing an implant in a patient's tongue, wherein the implant has first and second end portions that attach to tissue, and a tensioned medial portion between the first and second ends. The medial portion is configured to apply a pressure of less than a predetermined amount. Device systems associated with such methods are also provided.
摘要翻译：治疗气道疾病的方法包括将植入物放置在患者的舌中，其中植入物具有附接到组织的第一和第二端部以及第一和第二端之间的张紧的中间部分。内侧部分构造成施加小于预定量的压力。还提供了与这些方法相关的设备系统。

3. 发明申请

WO2011116384A3 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：WO2011116384A3
公开(公告)日：2012-01-19
申请号：PCT/US2011029218
申请日：2011-03-21
申请人： REVENT MEDICAL INC , GILLIS EDWARD M , POUTIATINE ANDREW , SHADDUCK JOHN H , TRUCKAI CSABA
发明人： GILLIS EDWARD M , POUTIATINE ANDREW , SHADDUCK JOHN H , TRUCKAI CSABA
IPC分类号： A61F5/56 , A61F2/00
CPC分类号： A61F5/566 , A61F2/00 , A61F5/56 , A61F2210/0004
摘要： A system for treating an airway disorder is provided with an implant body configured to conform to an airway-interface tissue site in a manner compatible with normal physiological function of the site. In some embodiments, the implant body includes an adjustment element configured to allow in-situ adjustment of the implant body between first and second tensioning forces applied to the site. Methods of using such systems are also provided.
摘要翻译：一种用于治疗气道障碍的系统设置有植入体，其构造成以与该部位的正常生理功能相适应的方式与气道界面组织部位一致。在一些实施例中，植入物主体包括调整元件，其被配置为允许植入物本体在施加到部位的第一和第二张力之间进行原位调整。还提供了使用这种系统的方法。

4. 发明申请

WO2008137428A3 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2008137428A3
公开(公告)日：2009-11-12
申请号：PCT/US2008061911
申请日：2008-04-29
申请人： DFINE INC , TRUCKAI CSABA , SHADDUCK JOHN H , LUZZI ROBERT
发明人： TRUCKAI CSABA , SHADDUCK JOHN H , LUZZI ROBERT
IPC分类号： A61L24/02 , A61B17/56 , A61L27/02
CPC分类号： A61B17/8822 , A61B17/88 , A61B17/8805 , A61B17/8811 , A61B17/8816 , A61B17/8836
摘要： The present invention relates in certain embodiments to systems and methods for treating bone, such as vertebral compression fractures. In one embodiment, a method includes controllably applying energy from an energy source to a bone cement volume outside of a patient's body to selectively accelerate the polymerization rate of the bone fill material volume prior to introduction of the bone fill material into a bone. The method further includes sequentially introducing a plurality of cement carrying structures with said accelerated polymerization rate bone cement volume into the bone. A system for use in said method includes at least one elongated cement-carrying structure sized to carry a bone cement volume therein and an energy source operatively coupleable to the cement- carrying structure. The energy source applies energy to the bone cement volume to selectively accelerate a polymerization rate thereof. An elongated injector is insertable into the bone and has a passageway that removably receives the elongated cement- carrying structure to allow delivery of the accelerated polymerization rate bone cement into the bone.
摘要翻译：本发明在某些实施方案中涉及用于治疗骨的系统和方法，例如椎体压缩性骨折。在一个实施例中，一种方法包括将能量源可控地施加到患者身体外部的骨水泥体积，以在将骨填充材料引入骨骼之前选择性地加速骨填充材料体积的聚合速率。该方法还包括将具有所述加速聚合速率骨水泥体积的多个水泥承载结构顺序地引入骨中。用于所述方法的系统包括尺寸适于承载骨水泥体积的至少一个细长的水泥承载结构，以及可操作地连接到承载结构的能量源。能量源将能量施加到骨水泥体积以选择性地加速其聚合速率。细长的注射器可插入到骨中，并且具有可移除地容纳细长的水泥承载结构以允许将加速的聚合速率骨水泥输送到骨中的通道。

5. 发明申请

WO2005052959A2 POLYMER COMPOSITIONS EXHIBITING A PTC PROPERTY AND METHOD OF FABRICATION 审中-公开
标题翻译：聚合物组合物展示PTC性能和制造方法
公开(公告)号：WO2005052959A2
公开(公告)日：2005-06-09
申请号：PCT/US2004039251
申请日：2004-11-18
申请人： SURGRX INC , TRUCKAI CSABA , SHADDUCK JOHN H
发明人： TRUCKAI CSABA , SHADDUCK JOHN H
IPC分类号： A61B18/14 , H05B3/14 , H01C
CPC分类号： H05B3/146 , A61B18/14 , H05B2203/02
摘要： Various embodiments of the invention provide polymeric compositions including PTC composites that exhibit highly non-linear PTC effects together with extremely rapid, repeatable switching within a predetermined temperature range. In one embodiment, the polymer composite includes a polymer base material with dispersed conductive particles that have very low densities and very low thermal conductivity properties. The conductive particle component can comprise hollow glass microspheres to provide low mass and low thermal conductivity properties together with a nanoscale conductive cladding of silver or gold. The conductively clad microspheres have a core portion with a bulk density of less than about 2.0 g/cm3 and a mean thermal conductivity of less than about 5.0 W/m-oK.
摘要翻译：本发明的各种实施方案提供了包含PTC复合材料的聚合物组合物，其在预定温度范围内显示高度非线性的PTC效应以及非常快速，可重复的切换。在一个实施方案中，聚合物复合材料包括具有分散的导电颗粒的聚合物基体材料，其具有非常低的密度和非常低的导热性能。导电颗粒组分可以包括中空玻璃微球，以提供低质量和低导热性以及银或金的纳米级导电包层。导电包覆的微球体具有堆积密度小于约2.0g / cm 3并且平均热导率小于约5.0W / m-oK的核心部分。

6. 发明申请

WO2012075503A3 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：WO2012075503A3
公开(公告)日：2012-09-27
申请号：PCT/US2011063323
申请日：2011-12-05
申请人： REVENT MEDICAL INC , GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA
发明人： GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA
IPC分类号： A61F5/56 , A61F2/04
CPC分类号： A61F5/566
摘要： An implant for treating an obstructive airway disorder includes an elongate implant body configured for implanting in airway-interface tissue. At least a portion of the elongate body carries a light transmission material for permitting light transmission therein. Systems and methods of treating an airway disorder comprising implanting an implant in an airway-interface tissue are also provided.
摘要翻译：用于治疗阻塞性气道障碍的植入物包括构造成用于植入气道界面组织中的细长植入体。细长体的至少一部分携带用于允许光透射的透光材料。还提供了治疗气道障碍的系统和方法，包括将植入物植入气道界面组织中。

7. 发明申请

WO2012018545A2 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：WO2012018545A2
公开(公告)日：2012-02-09
申请号：PCT/US2011044880
申请日：2011-07-21
申请人： REVENT MEDICAL INC , GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA , POUTIATINE ANDREW , BUSCEMI PAUL J
发明人： GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA , POUTIATINE ANDREW , BUSCEMI PAUL J
IPC分类号： A61F5/56 , A61F2/02
CPC分类号： A61F5/566
摘要： A method of treating an airway disorder includes placing an implant in a patient's tongue, wherein the implant has first and second end portions that attach to tissue, and a tensioned medial portion between the first and second ends. The medial portion is configured to apply a pressure of less than a predetermined amount. Device systems associated with such methods are also provided.
摘要翻译：治疗气道障碍的方法包括将植入物放置在患者舌头中，其中植入物具有连接到组织的第一和第二端部以及在第一和第二端之间的张紧的中间部分。内侧部分构造成施加小于预定量的压力。还提供了与这种方法相关联的设备系统。

8. 发明申请

WO2011146930A3 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：WO2011146930A3
公开(公告)日：2012-04-05
申请号：PCT/US2011037584
申请日：2011-05-23
申请人： REVENT MEDICAL INC , GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA , POUTIATINE ANDREW , BUSCEMI PAUL J
发明人： GILLIS EDWARD M , SHADDUCK JOHN H , TRUCKAI CSABA , POUTIATINE ANDREW , BUSCEMI PAUL J
IPC分类号： A61F5/56 , A61F2/02
CPC分类号： A61F2/00 , A61F5/566 , A61F2210/0004
摘要： A system for treating an airway disorder is provided with an implant body configured to conform to an airway-interface tissue site in a manner compatible with normal physiological function of the site. In some embodiments, the implant body has first and second end portions and a medial portion. The implant body also includes a coupler configured to couple the end portions to one another such that the medial portion encircles targeted tissue. Methods of using such systems are also provided.
摘要翻译：一种用于治疗气道障碍的系统设置有植入体，其构造成以与该部位的正常生理功能相适应的方式与气道界面组织部位一致。在一些实施例中，植入体具有第一和第二端部和中间部分。植入体还包括耦合器，其被配置为将端部部分彼此耦合，使得内侧部分围绕目标组织。还提供了使用这种系统的方法。

9. 发明申请

WO2008097855A3 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2008097855A3
公开(公告)日：2009-07-23
申请号：PCT/US2008052821
申请日：2008-02-01
申请人： DFINE INC , LUZZI ROBERT , SHADDUCK JOHN H , TRUCKAI CSABA
发明人： LUZZI ROBERT , SHADDUCK JOHN H , TRUCKAI CSABA
IPC分类号： A61L24/02 , A61L24/06 , A61L27/02 , A61L27/16 , A61L27/50
CPC分类号： A61L24/0084 , A61B17/8822 , A61B17/8836 , A61B2017/00026 , A61B2017/00088 , A61B2017/00101 , A61L24/02 , A61L24/06 , A61L27/16 , A61L27/46 , A61L27/50 , A61L2430/02 , C08L33/12
摘要： Bone cement formulations are provided that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures. In one embodiment, a settable bone cement includes a polymerizable composition with a powder component comprising an X-Ray contrast medium and a liquid component, wherein the setting time of the cement is at least about 25 minutes, at least about 30 minutes, at least about 35 minutes, and at least about 40 minutes.
摘要翻译：提供骨水泥配方，其具有用于椎体成形术和其它成骨术程序的延长的工作时间。在一个实施方案中，可固化骨粘固剂包括具有包含X射线造影剂和液体组分的粉末组分的可聚合组合物，其中所述胶泥的凝固时间至少为约25分钟，至少约30分钟，至少约35分钟，以及至少约40分钟。

10. 发明申请

WO2006062939A3 BONE TREATMENT SYSTEMS AND METHODS 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：WO2006062939A3
公开(公告)日：2006-08-03
申请号：PCT/US2005044055
申请日：2005-12-06
申请人： DFINE INC , TRUCKAI CSABA , SHADDUCK JOHN H , LUZZI ROBERT
发明人： TRUCKAI CSABA , SHADDUCK JOHN H , LUZZI ROBERT
IPC分类号： A61F2/28 , A61B18/00 , A61L24/02
CPC分类号： A61B18/14 , A61B17/7095 , A61B17/7098 , A61B17/8811 , A61B17/8822 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2018/00565 , A61F2/44 , A61L27/50 , A61L2430/38
摘要： The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. A system 100 utilizes Rf energy in combination a conductive bone fill material 120 for polymerizing the surface of the inflow plume 165 to control the geometry of the fill material 120 and the application of force caused by inflows of fill material 120. In another embodiment, the method of treating bone includes injecting a volume of fill material 120 into a bone and selectively modifying a viscosity of a selected portion of the bone fill material 120 to control the direction of flow of the fill material 120 within the bone 90. The method can also include controlling at least one flow parameter of the flow of bone fill material 120. A system 100 for treating bone using this method includes an introducer 110A, 110B for delivering fill material 120 into the bone 90 and an energy source 125A selectively coupleable to the fill material 120 to alter the viscosity of the fill material 120 as it flows out of the introducer 110A, 110B.
摘要翻译：本发明在某些实施方案中涉及用于治疗诸如椎骨压缩性骨折之类的骨整形手术的医疗装置。更具体地说，本发明的实施例涉及通过控制引入松质骨的填充材料的几何形状来可控地恢复椎体高度的器械和方法。系统100利用Rf能量结合导电骨填充材料120来聚合流入羽流165的表面以控制填充材料120的几何形状和由填充材料120的流入引起的力的施加。在另一个实施例中，治疗骨的方法包括将一定体积的填充材料120注入到骨中并选择性地改变骨填充材料120的选定部分的粘度以控制填充材料120在骨90内的流动方向。该方法还可以包括控制骨填充材料120的流动的至少一个流动参数。用于使用该方法治疗骨骼的系统100包括用于将填充材料120输送到骨骼90中的导入器110A，110B以及可选择地与填充物耦合的能量源125A 材料120以在填充材料120流出导引器110A，110B时改变填充材料120的粘度。

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