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1. 发明申请

WO2017192558A1 THERMOACOUSTIC IMAGE-GUIDED MICROWAVE THERAPY SYSTEM 审中-公开
标题翻译：热声图像引导微波治疗系统
公开(公告)号：WO2017192558A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/030599
申请日：2017-05-02
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人： WITTE, Russell , XIN, Hao , MARTIN, Diego
IPC分类号： A61N7/02
CPC分类号： A61B18/1815 , A61B2017/00053 , A61B2017/00106 , A61B2017/008 , A61B2018/00333 , A61B2018/00446 , A61B2018/00529 , A61B2018/00577 , A61B2018/00642 , A61B2018/00809 , A61B2018/1853 , A61B2018/1884 , A61B2090/378 , A61N1/403 , A61N5/025 , A61N2005/027
摘要： A method and system capable of applying microwave therapy guided by thermoacoustic imaging and/or thermoacoustic thermometry is disclosed. The system includes a thermoacoustic imaging system and/or a thermoacoustic thermometry system that generate(s) a map of a region of interest; and a microwave therapy system that targets the region of interest using the 5 map, and that applies the microwave therapy to the targeted region of interest. Treatment of the targeted region of interest may be employed by the microwave therapy system using real-time feedback from the thermoacoustic imaging system and/or the thermoacoustic thermometry system. Imaging and therapy may be automatically co-registered.
摘要翻译：公开了一种能够应用通过热声成像和/或热声测温引导的微波疗法的方法和系统。该系统包括产生感兴趣区域的图的热声成像系统和/或热声测温系统; 以及使用该地图针对感兴趣区域的微波疗法系统，并且将微波疗法应用于目标感兴趣区域。利用来自热声成像系统和/或热声测温系统的实时反馈，微波治疗系统可以使用目标感兴趣区域的治疗。成像和治疗可能会自动共同注册。

2. 发明申请

WO2017210686A1 ACOUSTOELECTRIC IMAGE-GUIDED THERAPY 审中-公开
标题翻译：声学图像引导治疗
公开(公告)号：WO2017210686A1
公开(公告)日：2017-12-07
申请号：PCT/US2017/035963
申请日：2017-06-05
申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人： WITTE, Russell , INGRAM, Charles M. , LI, Qian , QIN, Yexian
IPC分类号： A61B5/05 , A61B5/06 , A61B8/13
摘要： An acoustoelectric image-guided therapy system and method for applying acoustoelectric image-guided therapy are disclosed. Embodiments are directed to therapy systems and methods that utilize and are based on acoustoelectric imaging. The acoustoelectric imaging may be combined with focused therapies such as ultrasound, ablation, or hyperthermia for treatment of, for example, acute or chronic conduction abnormalities (e.g., neuropathy, arrhythmia, epilepsy, etc.). Current-density maps are obtained near the region of interest using acoustoelectric imaging techniques. Targeting of the region of interest is then identified for therapy based on the current-density maps. Treatment of the targeted region of interest is then employed while optionally monitoring bioelectric properties using real-time feedback from the acoustoelectric imaging. Imaging and therapy may be automatically co-registered. Standard electrophysiology (e.g., ENG, ECG, EEG, etc.) may be performed simultaneously with the same electrodes used for the acoustoelectric imaging.
摘要翻译：公开了一种用于施加声电图像引导治疗的声电图像引导治疗系统和方法。实施例针对利用并基于声电成像的治疗系统和方法。声电成像可与用于治疗例如急性或慢性传导异常（例如神经病，心律失常，癫痫等）的聚焦疗法（例如超声，消融或高温）组合。使用声电成像技术在感兴趣区域附近获得电流密度图。然后基于电流密度图识别目标区域的靶向用于治疗。然后使用目标感兴趣区域的处理，同时可选地使用来自声电成像的实时反馈来监测生物电特性。成像和治疗可以自动共同注册。标准电生理学（例如，ENG，ECG，EEG等）可以与用于声电成像的相同电极同时执行。

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