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    • 5. 发明申请
    • SYSTEM AND METHODS FOR IN-LINE MONITORING OF PARTICLES IN OPAQUE FLOWS AND SELECTIVE OBJECT MANIPULATION IN MULTI-COMPONENT FLOW
    • 在OPAQUE流中对粒子进行在线监测的系统和方法以及多组分流中的选择性对象操作
    • WO2010004516A1
    • 2010-01-14
    • PCT/IB2009/052974
    • 2009-07-08
    • IPGRIP, INC.SCHWEIGER, MartinMAVLIEV, RashidMAVLIEV, Andrew
    • MAVLIEV, RashidMAVLIEV, Andrew
    • G01N15/00B01D43/00
    • G01N15/1404B01D43/00G01N15/1425G01N35/1097G01N2015/0092
    • Systems and methods are disclosed for particle monitoring, in particular in-line particle monitoring and selective object manipulation in multi-component flow. An exemplary system can include a detection system for the monitoring of a component, such as a particle in a opaque flow carrier. An exemplary system includes confining a flowable sample which is opaque to at least a first range of wavelengths of light waves; compressing the flowable sample in a first direction while confining the sample in a second direction parallel to a flow direction of the flowable sample and orthogonal to the first direction, while elongating the sample in a third direction orthogonal to the first and second directions. When the sample is compressed in the first direction, the sample becomes transparent to at least one of the wavelengths in the first range of wavelengths enabling optical means for particle detection. The system can also include a device such as a valve or actuator to manipulate the detected component from other components in the flow carrier. A controller or other processor can receive and process detected component data and distinguish a component of interest from the remaining flowable sample. Once the component is recognized, the controller synchronizes the flow manipulation device with the detection system to manipulate the detected component from the flow carrier.
    • 公开了用于粒子监测的系统和方法,特别是在多分量流中的在线粒子监测和选择性对象操作。 示例性系统可以包括用于监测部件(例如不透明流动载体中的颗粒)的检测系统。 示例性系统包括限制对至少第一波长波长的光波是不透明的可流动样品; 同时在与第一和第二方向正交的第三方向延伸样品的同时将样品限制在平行于可流动样品的流动方向并与第一方向正交的第二方向上,同时沿着第一方向压缩可流动样品。 当样品在第一方向被压缩时,样品变得透明,使得能够进行粒子检测的光学装置的第一波长范围中的至少一个波长。 该系统还可以包括诸如阀门或致动器的装置,以便从流动载体中的其它部件操纵检测到的部件。 控制器或其他处理器可以接收和处理检测到的组件数据并将感兴趣的组件与剩余的可流动样本区分开。 一旦识别出部件,控制器将流量操纵装置与检测系统同步,以便从流动载体中操纵检测到的部件。
    • 6. 发明申请
    • METHOD AND APPARATUS FOR DETECTING INDIVIDUAL PARTICLES IN A FLOWABLE SAMPLE
    • 用于检测可流动样品中的个体颗粒的方法和装置
    • WO2004005894A1
    • 2004-01-15
    • PCT/US2003/020640
    • 2003-07-01
    • MAVLIEV, Rashid
    • MAVLIEV, Rashid
    • G01N15/02
    • G01N15/1404G01N15/1459G01N2015/1406G01N2015/1409G01N2015/1413G01N2015/1497
    • An apparatus (100) and method are disclosed for the optical characterization of particles in highly concentrated systems (i.e. suspensions and dispersions, hereinafter referred to as the "sample"), such as solid-particle slurries and liquid-in-liquid (e.g. oil-in-water) emulsions, which do not require dilution of the samples. Reduction of the optical transparency of the sample, which is required to avoid the influence of multiple light scattering, is achieved by forming the sample into a sheet flow with controlled thickness. The sample transparency is measured by using a light extinction method and the sample thickness in the optical cell (102) is controlled in order to keep the sample transparency within a range of predetermined values. By this means, an improved efficiency of single-particle detection is achieved and the usual reduction of signal quality due to multiple light scattering is avoided.
    • 公开了一种用于光学表征高浓度系统(即悬浮液和分散体,以下称为“样品”)中的颗粒的装置(100)和方法,例如固体颗粒浆液和液体液体(例如油 - 水)乳液,其不需要稀释样品。 通过将样品形成具有受控厚度的片材流,实现了避免多次光散射影响所需的样品的光学透明度的降低。 通过使用消光方法测量样品透明度,并且控制光学单元(102)中的样品厚度,以将样品透明度保持在预定值的范围内。 通过这种方式,可以实现提高单粒子检测效率,避免由于多光散射引起的信号质量的普遍降低。