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1. 发明申请

WO2009151212A2 EXTERNAL PREPARATION COMPOSITION FOR SKIN COMPRISING GINSENG FLOWER OR GINSENG SEED EXTRACTS 审中-公开
标题翻译：金山花或金松籽提取物外用外用组合物
公开(公告)号：WO2009151212A2
公开(公告)日：2009-12-17
申请号：PCT/KR2009002206
申请日：2009-04-28
申请人： AMOREPACIFIC CORP , YEOM MYEONG HUN , LEE JIN YOUNG , HWANG JUNG SUN , PARK NOK HYUN , PARK JUN SEONG , KIM DUCK HEE , KIM HAN KON
发明人： YEOM MYEONG HUN , LEE JIN YOUNG , HWANG JUNG SUN , PARK NOK HYUN , PARK JUN SEONG , KIM DUCK HEE , KIM HAN KON
IPC分类号： A61K8/97 , A61K36/258 , A61P17/06 , A61P17/12 , A61P17/14 , A61Q5/00 , A61Q7/00 , A61Q17/04 , A61Q19/02 , A61Q19/08
CPC分类号： A61K36/258 , A61K8/97 , A61Q5/006 , A61Q5/12 , A61Q7/00 , A61Q19/02 , A61Q19/08
摘要： The present invention relates to uses of ginseng flower extract and ginseng seed extract. The ginseng seed extract comprises ginseng seed oil or ginseng seed skin extract. The uses include skin protection, antiaging, antiwrinkle, improvement of skin elasticity, whitening, skin moisturization, prevention and improvement of xeroderma such as atopy, keratin removal, sebum control, anti-inflammation, prevention and improvement of skin troubles such as acne, improvement of skin tone, prevention of hair loss, anti-dandruff, improvement of hair sheen and softness, enhancement of volume and elasticity of face or body's skin, and improvement of face or body lines.
摘要翻译：本发明涉及人参花提取物和人参种子提取物的用途。人参种子提取物包括人参种子油或人参种子皮肤提取物。用途包括皮肤保护，抗衰老，抗皱纹，改善皮肤弹性，美白，皮肤保湿，预防和改善诸如特应性，角蛋白去除，皮脂控制，抗炎，预防和改善皮肤麻烦如痤疮，改善的皮肤病的皮肤色调，防止脱发，防头皮屑，改善头发光泽和柔软度，增强面部或身体皮肤的体积和弹性，改善面部或身体线条。

2. 发明申请

WO2009107996A3 METHOD FOR FERMENTING NATURAL MATERIALS WITH SALT AND FERMENTED EXTRACTS PREPARED THEREFROM 审中-公开
标题翻译：用盐生产天然物质的方法及其制备的发酵提取物
公开(公告)号：WO2009107996A3
公开(公告)日：2010-01-07
申请号：PCT/KR2009000935
申请日：2009-02-27
申请人： AMOREPACIFIC CORP , PARK JUN SEONG , PARK HYE YOON , LEE JIN YOUNG , KIM EUN JOO , KWAK IL YOUNG , SUH KYUNG HEE , KIM DUCK HEE , KIM HAN KON
发明人： PARK JUN SEONG , PARK HYE YOON , LEE JIN YOUNG , KIM EUN JOO , KWAK IL YOUNG , SUH KYUNG HEE , KIM DUCK HEE , KIM HAN KON
IPC分类号： A23L1/105
CPC分类号： A61K8/97 , A23L7/104 , A23L33/105 , A61K36/75 , A61K36/752 , A61K2800/85 , A61Q19/00
摘要： The present invention relates to a method for fermenting natural materials with salt and fermented extracts prepared therefrom. More particularly, the disclosed method comprises: adding the predetermined amount of salts to the natural materials such as oriental medicines and cereals and then naturally fermenting the above materials; and extracting the mixture in solvent. Accordingly, the invention can remove bad smells and prevent the growth of various germs such as putrefactive bacteria, Escherichia coli, and anaerobic bacteria which are harmful to the human body. Also, the method has fewer side effects and is safer than conventional fermentation methods.
摘要翻译：本发明涉及一种用盐发酵天然物质的方法和由其制备的发酵提取物。更具体地说，所公开的方法包括：将预定量的盐加入天然物质如东方药物和谷物中，然后天然发酵上述物质; 并在溶剂中萃取混合物。因此，本发明可以除去对人体有害的各种细菌，例如腐败菌，大肠杆菌，厌氧菌等不良气味。此外，该方法具有较少的副作用，并且比常规发酵方法更安全。

3. 发明申请

WO2009107996A2 METHOD FOR FERMENTING NATURAL MATERIALS WITH SALT AND FERMENTED EXTRACTS PREPARED THEREFROM 审中-公开
标题翻译：用盐和发酵剂提取天然材料的方法
公开(公告)号：WO2009107996A2
公开(公告)日：2009-09-03
申请号：PCT/KR2009000935
申请日：2009-02-27
申请人： AMOREPACIFIC CORP , PARK JUN SEONG , PARK HYE YOON , LEE JIN YOUNG , KIM EUN JOO , KWAK IL YOUNG , SUH KYUNG HEE , KIM DUCK HEE , KIM HAN KON
发明人： PARK JUN SEONG , PARK HYE YOON , LEE JIN YOUNG , KIM EUN JOO , KWAK IL YOUNG , SUH KYUNG HEE , KIM DUCK HEE , KIM HAN KON
IPC分类号： A23L1/105
CPC分类号： A61K8/97 , A23L7/104 , A23L33/105 , A61K36/75 , A61K36/752 , A61K2800/85 , A61Q19/00
摘要： The present invention relates to a method for fermenting natural materials with salt and fermented extracts prepared therefrom. More particularly, the disclosed method comprises: adding the predetermined amount of salts to the natural materials such as oriental medicines and cereals and then naturally fermenting the above materials; and extracting the mixture in solvent. Accordingly, the invention can remove bad smells and prevent the growth of various germs such as putrefactive bacteria, Escherichia coli, and anaerobic bacteria which are harmful to the human body. Also, the method has fewer side effects and is safer than conventional fermentation methods.
摘要翻译：本发明涉及用盐发酵天然材料的方法和由其制备的发酵提取物。更具体地说，所公开的方法包括：将预定量的盐加入天然材料如东方药物和谷物中，然后自然发酵上述材料; 并在溶剂中萃取混合物。因此，本发明可去除不良气味并防止对人体有害的各种细菌如腐败菌，大肠杆菌和厌氧菌的生长。此外，该方法副作用较少，比传统发酵方法更安全。

4. 发明申请

WO2010056012A3 METHOD FOR QUANTIFYING SKIN CHANGES CAUSED BY SIX EXTERNAL EVILS AND METHOD FOR SCREENING SKIN CONDITION-IMPROVING MATERIALS USING THE SAME 审中-公开
标题翻译：用于定量六种外部因素引起的皮肤变化的方法和使用其来筛选皮肤状况的方法 - 改善材料
公开(公告)号：WO2010056012A3
公开(公告)日：2010-09-30
申请号：PCT/KR2009006480
申请日：2009-11-05
申请人： AMOREPACIFIC CORP , LEE JIN YOUNG , KWON SUN SANG , YEOM MYEONG HOON , KIM DUCK HEE , KIM HAN KON
发明人： LEE JIN YOUNG , KWON SUN SANG , YEOM MYEONG HOON , KIM DUCK HEE , KIM HAN KON
IPC分类号： C12Q1/16
CPC分类号： G01N33/53 , C12Q1/02 , C12Q1/30 , C12Q1/32 , C12Q1/68 , C12Q1/686 , G01N33/5044 , G01N2500/04
摘要： Disclosed herein are a method for quantifying skin changes caused by six external evils and a method of screening skin condition-improving materials using the quantification method. More specifically, disclosed are a method of measuring cellular changes caused by external stimuli in a skin cell culture system, in which the degree of cellular changes obtained by applying suitable stimuli of six external evils to skin cells being cultured is measured by cellular biochemical methods, such that the conceptual effects of six external evils suggested in the prior art can be scientifically and quantitatively expressed, and a method of screening skin condition-improving materials using the measurement method.
摘要翻译：本文公开了一种量化六种外部病害引起的皮肤变化的方法和使用定量方法筛选皮肤状况改善材料的方法。更具体地，公开了测量皮肤细胞培养系统中由外部刺激引起的细胞变化的方法，其中通过细胞生物化学方法测量通过对正在培养的皮肤细胞施加六种外部恶性的合适刺激而获得的细胞变化程度，使得现有技术中提出的六种外部邪恶的概念效应可以被科学地和定量地表达，以及使用测量方法筛选皮肤状况改善材料的方法。

5. 发明申请

WO2012173383A3 SKIN COMPOSITION FOR EXTERNAL USE CONTAINING CRYPTOTANSHINONE AS ACTIVE INGREDIENT 审中-公开
标题翻译：含有CRYPTOTANSHINONE作为活性成分的外用皮肤组合物
公开(公告)号：WO2012173383A3
公开(公告)日：2013-03-14
申请号：PCT/KR2012004647
申请日：2012-06-13
申请人： AMOREPACIFIC CORP , LEE OK CHAN , YEOM MYEONG HUN , CHO GA YOUNG , LEE JIN YOUNG
发明人： LEE OK CHAN , YEOM MYEONG HUN , CHO GA YOUNG , LEE JIN YOUNG
IPC分类号： A61K31/58 , A61K31/343 , A61P17/00
CPC分类号： A61K31/343 , A61K9/5138 , A61K31/58
摘要： The present invention provides a skin composition for external use containing cryptotanshinone, an isomer thereof, a precursor thereof, a salt thereof, a hydrate thereof, or a solvate thereof as an active ingredient. The composition according to the present invention has the effects of suppressing skin aging, smoothing skin wrinkles, skin whitening, skin moisturizing, improving atopic dermatitis, and improving skin tone and skin transparency.
摘要翻译：本发明提供了含有隐丹参酮，其异构体，其前体，其盐，其水合物或其溶剂合物作为活性成分的外用皮肤组合物。根据本发明的组合物具有抑制皮肤老化，平滑皮肤皱纹，皮肤美白，皮肤保湿，改善特应性皮炎，改善肤色和皮肤透明度的效果。

6. 发明申请

WO2012173382A2 SKIN COMPOSITION FOR EXTERNAL USE CONTAINING TANSHINONE II A AS ACTIVE INGREDIENT 审中-公开
标题翻译：含有TANSHINONE II A外用的皮肤组合物作为活性成分
公开(公告)号：WO2012173382A2
公开(公告)日：2012-12-20
申请号：PCT/KR2012004644
申请日：2012-06-13
申请人： AMOREPACIFIC CORP , LEE OK CHAN , YEOM MYEONG HUN , CHO GA YOUNG , LEE JIN YOUNG
发明人： LEE OK CHAN , YEOM MYEONG HUN , CHO GA YOUNG , LEE JIN YOUNG
IPC分类号： A61K31/343 , A61K8/33 , A61K8/49 , A61Q19/02
CPC分类号： A61K8/4973 , A61K8/0208 , A61K31/343 , A61Q1/02 , A61Q1/06 , A61Q19/00 , A61Q19/02
摘要： The present invention provides a skin composition for external use containing Tanshinone II A, an isomer thereof, a precursor thereof, a salt thereof, a hydrate thereof, or a solvate thereof as an active ingredient. The composition according to the present invention has the effects of skin whitening, skin moisturizing, and improving skin tone and skin transparency.
摘要翻译：本发明提供了含有丹参酮IIA，其异构体，其前体，其盐，其水合物或其溶剂化物作为活性成分的外用皮肤组合物。根据本发明的组合物具有皮肤美白，皮肤保湿和改善肤色和皮肤透明度的作用。

7. 发明申请

WO2011159098A2 METHOD FOR PREPARING BROUSSONETIA KAZINOKI EXTRACT 审中-公开
标题翻译：制备高锰酸钾提取物的方法
公开(公告)号：WO2011159098A2
公开(公告)日：2011-12-22
申请号：PCT/KR2011004380
申请日：2011-06-15
申请人： AMOREPACIFIC CORP , LIM HYUNG JUN , LEE JIN YOUNG , PARK SUN YOUNG , AN SOON AE , LEE CHAN WOO , KIM EUN JOO , KIM JUN OH , HAN SANG HUN , KIM HAN KON
发明人： LIM HYUNG JUN , LEE JIN YOUNG , PARK SUN YOUNG , AN SOON AE , LEE CHAN WOO , KIM EUN JOO , KIM JUN OH , HAN SANG HUN , KIM HAN KON
IPC分类号： A61K36/60 , A61K8/97 , A61P17/00 , A61Q19/00 , A61Q19/02
CPC分类号： A61K36/60 , A61K8/97 , A61K2800/805 , A61Q19/02
摘要： The present invention provides a method for preparing a Broussonetia kazinoki extract, comprising the following steps: solvent extracting Broussonetia kazinoki; isolating the Broussonetia kazinoki extract, extracted in the previous step; and crystallizing the Broussonetia kazinoki extract isolated in the previous step. It is possible to prepare a Broussonetia kazinoki extract having a remarkable skin whitening effect and excellent stability through the method for preparing a Broussonetia kazinoki extract.
摘要翻译：本发明提供了一种制备布鲁氏酵母提取物的方法，包括以下步骤：溶剂提取布鲁氏菌属（Broussonetia kazinoki）; 在前一步骤中提取的Broussonetia kazinoki提取物; 并结晶在前一步骤中分离的布鲁氏菌（Broussonetia kazinoki）提取物。通过制备布鲁氏菌（Broussonetia kazinoki）提取物的方法，可以制备具有显着的皮肤美白效果和优异的稳定性的布鲁氏菌（Broussonetia kazinoki）提取物。

8. 发明申请

WO2012074246A3 METHOD FOR SCREENING SKIN AGING-RELATED GENES AND MATERIALS FOR PREVENTING SKIN AGING 审中-公开
标题翻译：用于筛选皮肤老化相关基因和预防皮肤老化的材料的方法
公开(公告)号：WO2012074246A3
公开(公告)日：2012-10-04
申请号：PCT/KR2011009057
申请日：2011-11-25
申请人： AMOREPACIFIC CORP , SNU R&DB FOUNDATION , SON EUI DONG , LEE JIN YOUNG , NA YONG JU , KIM HYAE KYOUNG , KIM JI HYUN , AHN SOO MI , KIM HAN KON , CHUNG JIN HO , PARK CHI HYUN , SEO EUN YOUNG , LEE MIN JUNG , OH INN GYUNG , YOON HYUN SUN
发明人： SON EUI DONG , LEE JIN YOUNG , NA YONG JU , KIM HYAE KYOUNG , KIM JI HYUN , AHN SOO MI , KIM HAN KON , CHUNG JIN HO , PARK CHI HYUN , SEO EUN YOUNG , LEE MIN JUNG , OH INN GYUNG , YOON HYUN SUN
IPC分类号： C12Q1/68 , C12N15/12
CPC分类号： C12Q1/6809 , C12Q1/6883 , C12Q2600/158
摘要： The present invention relates to a method for screening skin aging-specific genes and a method for screening anti-aging materials by controlling the expression of the genes. The invention can provide a new material having an effect on the prevention of skin aging and the treatment of skin diseases by obtaining new target genes related to skin aging and controlling the expression of the genes.
摘要翻译：本发明涉及一种筛选皮肤老化特异性基因的方法以及通过控制基因表达来筛选抗衰老材料的方法。本发明可以通过获得与皮肤老化相关的新靶基因并控制基因的表达，提供一种具有预防皮肤老化和皮肤病治疗效果的新材料。

9. 发明申请

WO2012141531A3 METHOD FOR SCREENING INHIBITORY SUBSTANCES TO INFLAMMATORY SKIN-AGING 审中-公开
标题翻译：用于筛选抑制性物质至炎性皮肤老化的方法
公开(公告)号：WO2012141531A3
公开(公告)日：2013-03-07
申请号：PCT/KR2012002825
申请日：2012-04-13
申请人： AMOREPACIFIC CORP , KIM JI SEONG , LEE JIN YOUNG , PARK JUN SEONG , CHOI HYANG TAE , KIM HAN BYUL , BAE JI HYUN
发明人： KIM JI SEONG , LEE JIN YOUNG , PARK JUN SEONG , CHOI HYANG TAE , KIM HAN BYUL , BAE JI HYUN
IPC分类号： C12Q1/02 , G01N33/15
CPC分类号： C12Q1/37 , G01N33/502 , G01N2333/8146 , G01N2500/10
摘要： The present invention relates to a method for screening inhibitory substances to inflammatory skin-aging comprising the following steps: treating immune cells with an inflammatory stimulant; treating skin cells with a candidate material; treating the skin cells that were treated with the candidate material with the immune cells treated with the inflammatory stimulant; and measuring the concentration of matrix metalloproteinase-1 (MMP-1) in the skin cells treated with the immune cells.
摘要翻译：本发明涉及一种筛选炎症皮肤老化抑制物质的方法，包括以下步骤：用炎症刺激剂处理免疫细胞; 用候选材料处理皮肤细胞; 用用炎症刺激剂处理的免疫细胞处理用候选物质处理的皮肤细胞; 并测量用免疫细胞处理的皮肤细胞中基质金属蛋白酶-1（MMP-1）的浓度。

10. 发明申请

WO2012008776A3 METHOD FOR PREPARING BROUSSONETIA KAZINOKI EXTRACTS, BROUSSONETIA KAZINOKI EXTRACTS PREPARED BY THE METHOD, AND COSMETIC COMPOSITION COMPRISING THE EXTRACTS 审中-公开
标题翻译：本发明涉及一种黄芩金合欢提取物的制备方法，以及由该提取物组成的化妆品组合物
公开(公告)号：WO2012008776A3
公开(公告)日：2012-08-23
申请号：PCT/KR2011005191
申请日：2011-07-14
申请人： AMOREPACIFIC CORP , KWON SUN SANG , LEE JIN YOUNG , CHUNG HAN SUN , KIM SO YEON , AN SUNG JUN
发明人： KWON SUN SANG , LEE JIN YOUNG , CHUNG HAN SUN , KIM SO YEON , AN SUNG JUN
IPC分类号： A61K8/97 , A61Q19/00 , A61Q19/08
CPC分类号： A61Q19/00 , A61K8/97 , A61K2800/85 , A61Q15/00 , A61Q17/005 , A61Q19/02 , A61Q19/08
摘要： The present invention relates to a method for preparing Broussonetia kazinoki extracts, to Broussonetia kazinoki extracts prepared by the method, and to a cosmetic composition comprising the extracts. More particularly, the present invention relates to a method for preparing Broussonetia kazinoki extracts, which involves extracting Broussonetia kazinoki using an ultra-high-pressure technique, a supercritical technique, or an oil-extraction technique, to thereby increase active ingredients and improve skin-whitening, anti-aging, anti-wrinkle, skin-moisturizing and skin-elasticity-enhancing effects. The present invention also relates to Broussonetia kazinoki extracts prepared by the method, and to a cosmetic composition comprising the extracts. In addition, the present invention relates to a method for fermenting Broussonetia kazinoki or extracts thereof, to fermented extracts prepared by the method, and to a cosmetic composition comprising the fermented extracts. More particularly, the present invention relates to a method for fermenting Broussonetia kazinoki or the extracts thereof, which involves naturally fermenting Broussonetia kazinoki or extracts thereof, or ferments Broussonetia kazinoki or extracts thereof by adding a fermentation strain or a predetermined amount of salt, and extracting the fermented Broussonetia kazinoki or extracts thereof using a solvent, to thereby prevent the propagation of various bacteria such as putrefactive bacteria, colon bacteria and anaerobic bacteria, which are harmful to the human body, remove offensive odors, and improve skin-whitening, anti-aging, anti-wrinkle, skin-moisturizing, and skin-elasticity-enhancing effects as compared to conventional extracts. The present invention also relates to fermented extracts prepared by the method, and to a cosmetic composition comprising the fermented extracts.
摘要翻译：本发明涉及一种用于制备长寿花提取物的方法，一种由该方法制备的长寿花（Broussonetia kazinoki）提取物以及一种包含该提取物的化妆品组合物。更具体地说，本发明涉及一种用于制备构树提取物的方法，该方法包括使用超高压技术，超临界技术或油提取技术提取构树，从而增加活性成分并改善皮肤 - 美白，抗衰老，抗皱，保湿和增强皮肤弹性的功效。本发明还涉及通过该方法制备的构树（Broussonetia kazinoki）提取物和包含该提取物的化妆品组合物。另外，本发明涉及用于发酵构树或其提取物的发酵方法，通过该方法制备的发酵提取物以及包含发酵提取物的化妆品组合物。更具体地说，本发明涉及一种发酵Broussonetia kazinoki或其提取物的方法，涉及天然发酵Broussonetia kazinoki或其提取物，或通过添加发酵菌株或预定量的盐发酵Broussonetia kazinoki或其提取物，并提取使用溶剂的发酵构树或其提取物，从而防止对人体有害的各种细菌如腐败菌，结肠菌和厌氧菌的繁殖，除去难闻的气味，改善皮肤美白，与传统提取物相比，具有抗老化，抗皱，保湿和提高皮肤弹性的作用。本发明还涉及通过该方法制备的发酵提取物，并且涉及包含发酵提取物的化妆品组合物。

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