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1. 发明申请

WO2013080053A1 LENSES, SYSTEMS AND METHODS FOR PROVIDING CUSTOM ABERRATION TREATMENTS AND MONOVISION TO CORRECT PRESBYOPIA 审中-公开
标题翻译：镜片，系统和方法，用于提供自定义去除处理和单独校正PRESBYOPIA
公开(公告)号：WO2013080053A1
公开(公告)日：2013-06-06
申请号：PCT/IB2012/002937
申请日：2012-11-30
申请人： AMO GRONINGEN B.V. , CANOVAS VIDAL, Carmen , PIERS, Patricia, Ann , WEEBER, Hendrik, A.
发明人： CANOVAS VIDAL, Carmen , PIERS, Patricia, Ann , WEEBER, Hendrik, A.
IPC分类号： G02C7/02 , A61F2/14 , A61F2/16 , G02C7/04
CPC分类号： G02C7/028 , A61F2/145 , A61F2/1613 , A61F2/1621 , A61F2/1637 , A61F2002/1699 , G02C7/02 , G02C7/027 , G02C7/04 , G02C2202/22
摘要： An apparatus, such as lenses, a system and a method for providing custom ocular aberrations that provide higher visual acuity. This scaling version of a patient's aberration pattern may either attenuate or amplify the overall amount of ocular aberrations, to either correct or partially correct patient's aberrations in order to provide excellent vision in the first case, or to extend depth of focus in the second case. This customized scaled aberrations' pattern concept may be binocularly applied inducing customized monovision, in order to provide high visual acuity in a patient at least at near, far and intermediate distances. The apparatus, system and method may include obtaining an optimized binocular summation of both eyes of the patient, the optimized binocular summation including at least natural aberrations of the patient, a dominant and non dominant eye measure of the patient, and changes in both the dominant eye and non dominant measure due to the natural aberrations of the patient; designing a first lens solution to correct or partially correct dominant eye's aberrations according to an attenuated scaled version of patient's ocular aberrations in the dominant eye; and designing a second lens solution to provide an additional customized extension of depth of focus by the induction of scaled patterns of ocular aberrations in the non dominant eye.
摘要翻译：诸如透镜，系统和用于提供提供更高视力的定制眼睛像差的方法的装置。患者的像差图案的缩放版本可以衰减或放大眼睛像差的总量，以校正或部分校正患者的像差，以便在第一种情况下提供优异的视力，或者在第二种情况下提供焦点深度。这种定制的缩放像差图案概念可以双眼应用诱导定制单视觉，以便至少在近距离和远距离处在患者体内提供高视力。装置，系统和方法可以包括获得患者双眼的优化双目总和，优化的双眼求和包括患者的至少自然畸变，患者的显性和非优势眼睛测量以及两者的主要变化由于患者的自然异常，眼睛和非主要措施; 设计第一透镜解决方案以根据优势眼中患者眼睛像差的衰减缩放版本校正或部分矫正主眼的畸变; 以及设计第二透镜解决方案，以通过感应非优势眼睛中的眼睛像差的缩放图案来提供焦点深度的附加定制延伸。

2. 发明申请

WO2012024152A1 CUSTOMIZED INTRAOCULAR LENS POWER CALCULATION SYSTEM AND METHOD 审中-公开
标题翻译：定制的内窥镜镜头功率计算系统和方法
公开(公告)号：WO2012024152A1
公开(公告)日：2012-02-23
申请号：PCT/US2011/047370
申请日：2011-08-11
申请人： ABBOTT MEDICAL OPTICS INC. , CANOVAS VIDAL, Carmen , ARTAL, Pablo , VAN DER MOOREN, Marrie , PIERS, Patricia, Ann
发明人： CANOVAS VIDAL, Carmen , ARTAL, Pablo , VAN DER MOOREN, Marrie , PIERS, Patricia, Ann
IPC分类号： A61B3/10 , A61F2/16
CPC分类号： A61B3/103 , A61B3/0025 , A61F2/16 , A61F2/1637 , A61F2240/002
摘要： Selecting an optimal intraocular lens (IOL) from a plurality of lOLs for implanting in a subject eye, including measuring anterior corneal topography (ACT), axial length (AXL), and anterior chamber depth (ACD) of a subject eye; selecting a default equivalent refractive index depending on preoperative patient's stage or calculating a personalized value or introducing a complete topographic representation if posterior corneal data are available; creating a customized model of the subject eye with each of a plurality of identified intraocular lenses (IOL) implanted, performing a ray tracing through that model eye; calculating from the ray tracing a RpMTF or RMTF value; and selecting the IOL corresponding to the highest RpMTF or RMTF value for implanting in the subject eye.
摘要翻译：从多个lOL中选择最佳眼内透镜（IOL），用于植入目标眼睛，包括测量对象眼睛的前角膜形态（ACT），轴向长度（AXL）和前房深度（ACD）; 根据术前患者的阶段选择默认的等效折射率或计算个性化价值，或者如果后角膜数据可用，则引入完整的形态表示; 用植入的多个所识别的眼内透镜（IOL）中的每一个创建所述被检眼的定制模型，通过所述模型眼进行光线跟踪; 从光线跟踪计算RpMTF或RMTF值; 以及选择对应于最高RpMTF或RMTF值的IOL以植入对象眼睛。

3. 发明申请

WO2013028992A1 OPHTHALMIC DEVICES, SYSTEMS, AND METHODS FOR OPTIMIZING PERIPHERAL VISION 审中-公开
标题翻译： OPHTHALMIC设备，系统和优化外部视觉的方法
公开(公告)号：WO2013028992A1
公开(公告)日：2013-02-28
申请号：PCT/US2012/052311
申请日：2012-08-24
申请人： AMO GRONINGEN B.V. , LI, Kaccie, Y. , CANOVAS VIDAL, Carmen , WEEBER, Henk, A. , FRANSSEN, Luuk , VAN DER MOOREN, Marrie , PIERS, Patricia, A.
发明人： LI, Kaccie, Y. , CANOVAS VIDAL, Carmen , WEEBER, Henk, A. , FRANSSEN, Luuk , VAN DER MOOREN, Marrie , PIERS, Patricia, A.
IPC分类号： A61F2/16
CPC分类号： A61F2/1602 , A61F2/16 , A61F2/1618 , A61F2002/1699 , G02C7/044 , G02C2202/10
摘要： The present invention relates to devices, systems, and methods for optimizing peripheral vision. In particular, methods are disclosed which include utilizing particular characteristics of the retina in optimizing peripheral vision. Additionally, various IOL designs, as well as IOL implantation locations, are disclosed which optimize peripheral vision,
摘要翻译：本发明涉及用于优化周边视觉的装置，系统和方法。具体地，公开了包括利用视网膜的优化周边视觉的特定特征的方法。此外，公开了各种IOL设计以及IOL植入位置，其优化了周边视觉，

4. 发明申请

WO2012082898A1 APPARATUS, SYSTEM, AND METHOD FOR INTRAOCULAR LENS POWER CALCULATION USING A REGRESSION FORMULA INCORPORATING CORNEAL SPHERICAL ABERRATION 审中-公开
标题翻译：装置，系统和方法使用回归公式进行角膜透镜功率计算，并进行角膜球磨
公开(公告)号：WO2012082898A1
公开(公告)日：2012-06-21
申请号：PCT/US2011/064914
申请日：2011-12-14
申请人： ABBOTT MEDICAL OPTICS INC. , CANOVAS VIDAL, Carmen , ARTAL, Pablo
发明人： CANOVAS VIDAL, Carmen , ARTAL, Pablo
IPC分类号： A61F2/16
CPC分类号： A61B3/0025 , A61B3/10 , A61B3/107 , A61F2/1613 , A61F2/1637 , A61F2/164 , A61F2240/002
摘要： An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition. The empirically derived regression calculation includes at least a product of the corneal spherical aberration with an empirically derived corneal spherical aberration constant, and a mathematical indication of the at least one biometric parameter or one of the paraxial regression formulas commonly used in clinical practice to calculate IOL power in normal patients.
摘要翻译：眼内透镜，以及提供眼内透镜的系统和方法，其具有根据包括角膜球面像差的修改的修正回归定制的眼内透镜的至少一个特征。透镜，系统和方法可以指示以期望的光水平测量眼睛的至少一个生物特征参数，确定眼睛的期望的术后状态，获得眼睛的角膜球面像差，应用至少一个经验导出的回归计算，以及根据所述至少一个经验导出的回归计算的输出，预测所述眼内透镜的至少一个特征以获得所需的术后状态。经验导出的回归计算至少包括角膜球面像差与经验衍生的角膜球面像差常数的乘积，以及临床实践中通常用于计算IOL的至少一个生物特征参数或近轴回归公式之一的数学指示正常患者的功能

5. 发明申请

WO2023036841A1 LENSES HAVING DIFFRACTIVE PROFILES WITH ELEVATED SURFACE ROUGHNESS 审中-公开
公开(公告)号：WO2023036841A1
公开(公告)日：2023-03-16
申请号：PCT/EP2022/074906
申请日：2022-09-07
申请人： AMO GRONINGEN B.V.
发明人： WEEBER, Hendrik A. , ALARCON HEREDIA, Aixa , CANOVAS VIDAL, Carmen , GOUNOU, Franck , PIERS, Patricia A. , FARIA RIBEIRO, Miguel
IPC分类号： A61F2/16 , G02C7/04
摘要： Apparatuses, systems and methods for providing improved ophthalmic lenses, particularly intraocular lenses (IOLs), include features for reducing adverse optical effects from diffractive profiles of such a lens. Exemplary ophthalmic lenses can include an optic including a diffractive profile including a transition zone having an elevated surface roughness.

6. 发明申请

WO2019048707A1 INTRAOCULAR LENSES WITH CUSTOMIZED ADD POWER 审中-公开
公开(公告)号：WO2019048707A1
公开(公告)日：2019-03-14
申请号：PCT/EP2018/074493
申请日：2018-09-11
申请人： AMO GRONINGEN B.V.
发明人： CANOVAS VIDAL, Carmen , ROSÉN, Robert , VAN DER MOOREN, Marrie , PIERS, Patricia A.
IPC分类号： A61F2/16 , G02C7/04 , G02C7/02
摘要： Intraocular lenses with a base optical power and a customized add power. The add power is customized based on at least one of ocular biometry of an individual, position of the intraocular lens in the eye and a preferred reading distance.

7. 发明申请

WO2017137841A1 PROGRESSIVE POWER INTRAOCULAR LENS, AND METHODS OF USE AND MANUFACTURE 审中-公开
标题翻译：渐进功率人工晶状体，以及使用和制造方法
公开(公告)号：WO2017137841A1
公开(公告)日：2017-08-17
申请号：PCT/IB2017/000173
申请日：2017-02-09
申请人： AMO GRONINGEN B.V.
发明人： CANOVAS VIDAL, Carmen , ALARCON HEREDIA, Aixa , PIERS, Patricia, Ann , WEEBER, Hendrik, A.
IPC分类号： A61F2/16 , G02C7/04
CPC分类号： A61F2/1654 , A61F2/1618 , A61F2/1637 , A61F2/164 , G02B27/0075 , G02C7/027 , G02C7/028 , G02C7/04 , G02C7/044 , G02C7/066 , G02C7/068 , G02C2202/20 , G02C2202/22
摘要： Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.
摘要翻译：用于提供改进的眼内透镜（IOL）的设备，系统和方法包括用于减少多焦点折射透镜和延伸焦深透镜中的副作用（例如晕圈，眩光和最佳焦点位移）的特征。示例性眼科透镜可以包括基于两个或更多个合并光学区域的连续的功率递增非球面表面，非球面表面由单个非球面方程定义。连续功率渐进式人工晶状体可以减轻通常由突然的光学步骤引起的光学副作用。非球面光焦度渐进和非球面扩展深度聚焦透镜可与衍射透镜配置相结合，以进一步增强视觉表现，同时最大限度地减少视光不良效应。该组合可以提供比折射轮廓或衍射轮廓的单独焦深更大的增加的焦深。

8. 发明申请

WO2017137840A1 PROGRESSIVE POWER INTRAOCULAR LENS, AND METHODS OF USE AND MANUFACTURE 审中-公开
公开(公告)号：WO2017137840A1
公开(公告)日：2017-08-17
申请号：PCT/IB2017/000170
申请日：2017-02-09
申请人： AMO GRONINGEN B.V.
发明人： CANOVAS VIDAL, Carmen , ALARCON HEREDIA, Aixa , PIERS, Patricia, Ann , WEEBER, Hendrik, A.
IPC分类号： A61F2/16
CPC分类号： A61F2/1654 , A61F2/1618 , A61F2/1637 , A61F2/164 , G02B27/0075 , G02C7/027 , G02C7/028 , G02C7/04 , G02C7/044 , G02C7/066 , G02C7/068 , G02C2202/20 , G02C2202/22
摘要： Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

9. 发明申请

WO2016087914A1 APPARATUS, SYSTEMS AND METHODS FOR IMPROVING VISUAL OUTCOMES FOR PSEUDOPHAKIC PATIENTS 审中-公开
标题翻译：用于改善PSEUDOPHAKIC患者视觉结果的装置，系统和方法
公开(公告)号：WO2016087914A1
公开(公告)日：2016-06-09
申请号：PCT/IB2015/002109
申请日：2015-10-08
申请人： AMO GRONINGEN B.V.
发明人： ALARCON HEREDIA, Aixa , CANOVAS VIDAL, Carmen , ROSEN, Robert , WEEBER, Henk, A. , PIERS, Patricia, Ann
IPC分类号： G06F19/00
CPC分类号： G01M11/0292 , G01M11/0235 , G06F19/00 , G16H50/50
摘要： A system and method of characterizing through-focus visual performance of an IOL using metrics based on an area under the modulation transfer function for different spatial frequencies at different defocus positions of the IOL. Also disclosed is a system and method of characterizing through-focus visual performance of an IOL using a metric based on an area under a cross-correlation coefficient for an image of a target acquired by the IOL at different defocus positions of the IOL.
摘要翻译：使用基于在调制传递函数下的面积的度量的量测IOL的不同散焦位置处的不同空间频率来表征IOL的焦点视觉表现的系统和方法。还公开了一种使用基于IOL在不同离散位置处由IOL获取的目标的互相关系数下的面积的度量的度量来表征IOL的焦点视觉表现的系统和方法。

10. 发明申请

WO2020083829A1 INTRAOCULAR LENSES FOR REDUCING NEGATIVE DYSPHOTOPSIA 审中-公开
公开(公告)号：WO2020083829A1
公开(公告)日：2020-04-30
申请号：PCT/EP2019/078555
申请日：2019-10-21
申请人： AMO GRONINGEN B.V.
发明人： ROSEN, Robert , ZONNEVELD, Robin , ALARCON HEREDIA, Aixa , MEIJER, Sieger , STATE, Mihai , CANOVAS VIDAL, Carmen
IPC分类号： A61F2/16
摘要： Intraocular lenses for reducing negative dysphotopsia (ND) are described herein. An example ophthalmic lens can include an optic (200) with a central optical zone (225) disposed about the optical axis (OA) and an attenuation optical zone (220) disposed about the central optical zone (225), wherein the attenuation optical zone (220) is contiguous with the central optical zone (225), and wherein optical power of the ophthalmic lens is gradually reduced within the attenuation optical zone (220).

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