专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010151740A3 POLYCYCLIC DERIVATIVES OF PYRIDINE AND THEIR USE IN THE TREATMENT OF (INTER ALIA) RHEUMATOID ARTHRITIS AND SIMILAR DISEASES 审中-公开
标题翻译：吡啶的多环衍生物及其在治疗类风湿关节炎和类似疾病中的应用
公开(公告)号：WO2010151740A3
公开(公告)日：2011-03-31
申请号：PCT/US2010039942
申请日：2010-06-25
申请人： AMGEN INC
发明人： BUI MINNA HUE THANH , CHEN YI , CUSHING TIMOTHY D , DUQUETTE JASON A , FISHER BENJAMIN , GONZALEZ LOPEZ DE TURISO FELIX , HAO XIAOLIN , HE XIAO , JOHNSON MICHAEL G , LUCAS BRIAN
IPC分类号： C07D401/12 , A61K31/4375 , A61K31/444 , A61P19/02 , C07D401/14 , C07D471/04 , C07D487/04
CPC分类号： C07D487/04 , C07D401/12 , C07D401/14 , C07D471/04 , C07D473/34
摘要： Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110 activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia ( T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
摘要翻译：取代的双环杂芳基及其组合物，用于治疗一般炎症，关节炎，风湿性疾病，骨关节炎，炎性肠病，炎症性眼病，炎性或不稳定性膀胱病，牛皮癣，具有炎性成分的皮肤病，慢性炎症，包括但不限于（SLE），重症肌无力，类风湿性关节炎，急性播散性脑脊髓炎，特发性血小板减少性紫癜，多发性硬化症，Sjoegren综合征和自身免疫性溶血性贫血，包括所有形式的超敏反应的过敏性病症的自身免疫性疾病。本发明还包括（AML）骨髓增生异常综合征（MDS）骨髓增生性疾病（MPD）慢性骨髓性白血病（MPD）慢性粒细胞白血病（MPD）的治疗癌症的方法，所述方法用于治疗依赖于或关联于p110活性的癌症的方法包括但不限于白血病 C ML）T细胞急性淋巴细胞白血病（T-ALL）B细胞急性淋巴细胞白血病（B-ALL）非霍奇金淋巴瘤（NHL）B细胞淋巴瘤和实体瘤，如乳腺癌。

2. 发明申请

WO2010151740A4 POLYCYCLIC DERIVATIVES OF PYRIDINE AND THEIR USE IN THE TREATMENT OF (INTER ALIA) RHEUMATOID ARTHRITIS AND SIMILAR DISEASES 审中-公开
标题翻译：吡啶的多环衍生物及其在治疗（相互之间）炎症性脑脊髓炎和类似疾病中的用途
公开(公告)号：WO2010151740A4
公开(公告)日：2011-05-19
申请号：PCT/US2010039942
申请日：2010-06-25
申请人： AMGEN INC
发明人： BUI MINNA HUE THANH , CHEN YI , CUSHING TIMOTHY D , DUQUETTE JASON A , FISHER BENJAMIN , GONZALEZ LOPEZ DE TURISO FELIX , HAO XIAOLIN , HE XIAO , JOHNSON MICHAEL G , LUCAS BRIAN
IPC分类号： C07D401/12 , A61K31/4375 , A61K31/444 , A61P19/02 , C07D401/14 , C07D471/04 , C07D487/04
CPC分类号： C07D487/04 , C07D401/12 , C07D401/14 , C07D471/04 , C07D473/34
摘要： Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110 activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia ( T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
摘要翻译：取代的双环杂芳基和含有它们的组合物，用于治疗一般炎症，关节炎，风湿性疾病，骨关节炎，炎性肠病，炎症性眼病，炎性或不稳定性膀胱病，牛皮癣，皮肤炎症成分的投诉，慢性炎性病症不限于自身免疫性疾病如系统性红斑狼疮（SLE），重症肌无力，类风湿性关节炎，急性播散性脑脊髓炎，特发性血小板减少性紫癜，多发性硬化症，Sjoegren综合征和自身免疫性溶血性贫血，包括所有形式的超敏反应的过敏症状包括但不限于白血病，如急性骨髓性白血病（AML）骨髓增生异常综合征（MDS）骨髓增殖性疾病（MPD）慢性骨髓性白血病（MPD），慢性骨髓性白血病 C ML）T细胞急性淋巴细胞白血病（T-ALL）B细胞急性淋巴细胞白血病（B-ALL）非霍奇金淋巴瘤（NHL）B细胞淋巴瘤和实体瘤如乳腺癌。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式