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1. 发明申请

WO2012112836A1 UNIT DOSE BREAKABLE VIAL WITH INTEGRATED BRUSH APPLICATOR 审中-公开
标题翻译：具有集成式刷毛器的单元配件断开
公开(公告)号：WO2012112836A1
公开(公告)日：2012-08-23
申请号：PCT/US2012/025558
申请日：2012-02-17
申请人： ALLERGAN, INC. , SLOKOVIC, Lorens , GREMEL, Julie L.
发明人： SLOKOVIC, Lorens , GREMEL, Julie L.
IPC分类号： A61M35/00 , A45D34/04
CPC分类号： A61M35/006 , A45D34/04 , A45D34/042 , A45D40/0087 , A46B9/028 , A46D1/0207
摘要： A disposable sterile breakable vial includes a handle section and a vial section which are completely separable in response to a manually applied separation force. The vial section includes a sterile void dimensioned to contain a unit dose of a sterile therapeutic topical agent. An elongated member comprises a proximal portion supported by the handle section and a distal portion provided with a sterile applicator element, such as a brush. At least the applicator element is completely enclosed within the vial section with the applicator element immersed within the therapeutic topical agent. A hermetic seal between the handle and vial sections maintains sterility of at least the vial section prior to handle and vial section separation. Complete separation of the handle section and the vial section exposes the elongated member and the applicator element for topical application of the therapeutic agent saturating the applicator element.
摘要翻译：一次性无菌可破坏的小瓶包括手柄部分和小瓶部分，其可以响应于手动施加的分离力而完全分离。小瓶部分包括无菌空腔，其尺寸被设计成包含单位剂量的无菌治疗性外用剂。细长构件包括由手柄部分支撑的近端部分和设置有无菌施用器元件（例如刷子）的远端部分。至少涂抹器元件完全封闭在小瓶部分内，其中施用器元件浸入治疗性外用剂中。手柄和小瓶部之间的气密密封在手柄和小瓶部分离之前保持至少小瓶部分的无菌性。手柄部分和小瓶部分的完全分离暴露细长构件和施用器元件，用于局部施用饱和施用器元件的治疗剂。

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