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    • 1. 发明申请
    • TRIAZOLE PHOSPHONATE PESTICIDES
    • 三唑磷酸酯类农药
    • WO1995014385A1
    • 1995-06-01
    • PCT/GB1994002568
    • 1994-11-23
    • AGREVO UK LIMITEDWRIGHT, Gillian +hfLINDELL, Stephen, DavidFOSTER, Stephen, GeorgeMILLING, Richard, James
    • AGREVO UK LIMITEDWRIGHT, Gillian +hfWRIGHT, Brian, John +di
    • A01N57/24
    • C12Q1/18A01N57/24A01N61/00C07F9/6518
    • Compounds of formula (I), where Tr is optionally substituted 1,2,4-triazol-1-yl or 1.2.4-triazol-3-yl; A is a) Q, where Q is an optionally substituted chain containing 3 to 6 atoms, and in which (i) when the chain is of 3 atoms, at least one of the chain atoms is a hetero atom, (ii) when the chain comprises 4 carbon atoms, then the second carbon from the triazole is not substituted by optionally substituted hydroxy, and (iii) when the chain is of 3 to 5 atoms, the phospho group is not attached directly to an oxygen atom; or b) an optionally substituted three membered carbon chain or ring, in which two optional substituents can together with the chain atoms form a carbocyclic ring; and in which when A is a chain, various proviso apply, can be used for combating fungi. The compounds have been shown to be inhibitors of imidazole glycerol phosphate dehydratase. Many of the compounds are novel and these also have other pesticidal activity.
    • 式(I)化合物,其中Tr是任选取代的1,2,4-三唑-1-基或1.2,4-三唑-3-基; A是a)Q,其中Q是含有3至6个原子的任选取代的链,并且其中(i)当链为3原子时,至少一个链原子为杂原子,(ii)当 链包含4个碳原子,则来自三唑的第二碳不被任选取代的羟基取代,和(iii)当链为3至5个原子时,磷基不直接附着在氧原子上; 或b)任选取代的三元碳链或环,其中两个任选的取代基与链原子一起形成碳环; 并且当A是链时,各种附带条件适用,可用于对抗真菌。 这些化合物已被证明是咪唑甘油磷酸酯脱水酶的抑制剂。 许多化合物是新颖的,并且也具有其他杀虫活性。