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1. 发明申请

WO2021152019A1 INTRAVASCULAR BLOOD PUMP 审中-公开
公开(公告)号：WO2021152019A1
公开(公告)日：2021-08-05
申请号：PCT/EP2021/052002
申请日：2021-01-28
申请人： ABIOMED EUROPE GMBH
发明人： SPANIER, Gerd , SIESS, Thorsten
IPC分类号： A61M60/13 , A61M60/414 , A61M60/205 , A61M60/808 , A61M60/825
摘要： An intravascular blood pump (1) comprises a pumping device and a catheter (5). The pumping device comprises a drive shaft (12), a rotor (10) located at a distal end of the drive shaft (5), a housing (11), in which the rotor (10) is housed, and a distal bearing (14) for rotatably supporting a distal end of the rotor (10). The distal bearing (14) comprises a static support member (18), which protrudes into or up against the distal end of the rotor (10). The rotor (10) and housing (11) may be expandable, and the pin (19) may have a sufficient length to prevent disengagement of the pin (19) from the distal end of the rotor (10) when the rotor (10) and the housing (11) are in a collapsed state.

2. 发明申请

WO2018234454A1 CANNULA FOR INTRAVASCULAR BLOOD PUMP 审中-公开
公开(公告)号：WO2018234454A1
公开(公告)日：2018-12-27
申请号：PCT/EP2018/066590
申请日：2018-06-21
申请人： ABIOMED EUROPE GMBH
发明人： ABOULHOSN, Walid , SIESS, Thorsten , KIRCHHOFF, Frank
IPC分类号： A61M1/10 , A61M1/12
摘要： A method of manufacturing a cannula (4) for an intravascular blood pump comprises the steps of forming a first axial section (13) and a second axial section (15) of an elongate tubular body of the cannula (4) by dispensing a first liquid material and a second liquid material, respectively, onto a mandrel (7) by means of at least one dispenser (8). The mandrel (7) is rotated and the dispenser (8) moves relative to the mandrel (7) in an axial direction during dispensing of the liquid materials. The first and second axial sections (13,15) are formed so as to have different bending stiffnesses. The first and second liquid materials are dispensed onto the mandrel (7) such that the first and second liquid materials blend into each other to form a smooth transition area (14).

3. 发明申请

WO2017137604A1 BLOOD PUMP 审中-公开
标题翻译：血泵
公开(公告)号：WO2017137604A1
公开(公告)日：2017-08-17
申请号：PCT/EP2017/053074
申请日：2017-02-10
申请人： ABIOMED EUROPE GMBH
发明人： SIESS, Thorsten , ABOULHOSN, Walid , KIRCHHOFF, Frank , NIX, Christoph , SPANIER, Gerd
IPC分类号： A61M1/10 , A61M1/12
CPC分类号： A61M1/125 , A61M1/1008 , A61M1/122
摘要： A blood pump (1) comprises a pump section (2) and a flow cannula (3). A proximal end portion (14) of the flow cannula (3) is connected to the pump section (2) such that blood can enter the blood flow inlet (11), and a distal end portion (13) of the flow cannula (3) includes at least one blood flow-through opening (16) for blood to enter the flow cannula (3). The distal end portion (13) comprises an enlarged diameter portion (15), with at least a major portion of the blood flow-through opening (16) being disposed in the enlarged diameter portion (15). The blood pump (1) further comprises a sleeve (4) overlapping the enlarged diameter portion (15). The sleeve (4) has a structure that prevents its distal end (42) from bending radially inwards into the blood flow- through openings (16).
摘要翻译：血泵（1）包括泵部分（2）和流动套管（3）。流动套管（3）的近端部分（14）连接到泵部分（2），使得血液可以进入血流入口（11），并且流动套管（3）的远端部分）包括用于血液进入流动套管（3）的至少一个血液流通开口（16）。远端部分（13）包括直径扩大部分（15），其中血液流通开口（16）的至少大部分布置在扩大直径部分（15）中。血泵（1）还包括与扩大直径部分（15）重叠的套筒（4）。套筒（4）具有防止其远端（42）径向向内弯曲进入血液流通开口（16）的结构。

4. 发明申请

WO2016207293A1 BLOOD PUMP 审中-公开
标题翻译：血液泵
公开(公告)号：WO2016207293A1
公开(公告)日：2016-12-29
申请号：PCT/EP2016/064562
申请日：2016-06-23
申请人： ABIOMED EUROPE GMBH
发明人： SIESS, Thorsten , ABOULHOSN, Walid
IPC分类号： A61M1/10 , A61M1/12
CPC分类号： A61M1/101 , A61M1/1008 , A61M1/1012 , A61M1/1018 , A61M1/1034 , A61M1/122 , A61M1/125
摘要： A blood pump (1) comprises a pump casing (2) having a blood flow inlet (21) and a blood flow outlet (22), and an impeller (3) arranged in said pump casing (2) so as to be rotatable about an axis of rotation, wherein the impeller (3) has blades (31) sized and shaped for conveying blood from the blood flow inlet (21) to the blood flow outlet (22). The blood pump (1) further comprises an outflow cannula (4) having an upstream end portion (41), a downstream end portion (43) and an intermediate portion (42) extending between the upstream end portion (41) and the downstream end portion (43). The upstream end portion (41) of the outflow cannula (4) is connected to the pump casing (2) such that blood is conveyed from the blood flow outlet (22) of the pump casing (2) into and through the intermediate portion (42) of the outflow cannula (4) towards the downstream end portion (43) of the outflow cannula (4), wherein the downstream end portion (43) has a blood flow outlet (44) through which blood can exit the outflow cannula (4). At least a portion of the intermediate portion (42) of the outflow cannula (4) has an outer diameter that is larger than an outer diameter of the pump casing (2).
摘要翻译：血泵（1）包括具有血液流入口（21）和血液流出口（22）的泵壳体（2）和布置在所述泵壳体（2）中的叶轮（3），以便围绕旋转轴线，其中所述叶轮（3）具有尺寸和形状用于将血液从所述血流入口（21）输送到所述血流出口（22）的叶片（31）。血泵（1）还包括具有上游端部分（41），下游端部分（43）和在上游端部分（41）和下游端部（41）之间延伸的中间部分（42）的流出套管（4）部分（43）。流出套管（4）的上游端部分（41）连接到泵壳体（2），使得血液从泵壳体（2）的血流出口（22）输送到中间部分（4）的下游端部（43）的流出套管（4）的流体出口（42），其中下游端部（43）具有血液流出口（44） 4）。流出套管（4）的中间部分（42）的至少一部分的外径大于泵壳体（2）的外径。

5. 发明申请

WO2016001440A1 SHEATH FOR SEALED ACCESS TO A VESSEL 审中-公开
标题翻译：密封进入船只的密封
公开(公告)号：WO2016001440A1
公开(公告)日：2016-01-07
申请号：PCT/EP2015/065292
申请日：2015-07-06
申请人： ABIOMED EUROPE GMBH
发明人： SIESS, Thorsten , NIX, Christoph , KIRCHHOFF, Frank , HUNZIKER, Patrick
IPC分类号： A61M39/02
CPC分类号： A61M39/0247 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/122 , A61M1/125 , A61M39/0606 , A61M2039/0258 , A61M2039/0267 , A61M2039/0273 , A61M2039/0279 , A61M2039/062 , A61M2039/0626 , A61M2039/0633 , A61M2205/32 , A61M2205/3344 , A61M2205/6063 , A61M2230/30 , A61M2230/50
摘要： A sheath ( 10) for producing a fully sealed access to the interior of a vessel of an animal or human body comprises a base sheath (20) having a tubular body defining a pass-through channel (22). The base sheath (20) is adapted to be inserted into the vessel through a vessel aperture. A wall of the tubular body of the base sheath has a through channel (27). This channel extends in the wall from the distal end (20a) towards the proximal end (20b). The channel (27) can be present separately from the pass-through channel (22) of the base sheath or can form a sideways extension of the pass-through channel (22), at least at the distal end.. Such through channel (27) is adapted to conduct blood from the vessel to the proximal end of the sheath when the sheath has been inserted into a vessel.
摘要翻译：用于产生对动物或人体的容器内部的完全密封通路的护套（10）包括具有限定穿过通道（22）的管状体的基部护套（20）。基部护套（20）适于通过血管孔插入血管。基部护套的管状体的壁具有贯通通道（27）。该通道从远端（20a）延伸到壁的近端（20b）。通道（27）可以与基底护套的通过通道（22）分开存在，或者至少在远端处形成通过通道（22）的侧向延伸。这样的通道（ 27）适于在鞘被插入血管时将血液从血管传导到鞘的近端。

6. 发明申请

WO2022189585A1 PUMP INCLUDING A COMPRESSIBLE ROTOR HAVING OFFSET ROTOR BLADES 审中-公开
公开(公告)号：WO2022189585A1
公开(公告)日：2022-09-15
申请号：PCT/EP2022/056244
申请日：2022-03-10
申请人： ABIOMED EUROPE GMBH
发明人： SIESS, Thorsten , SPANIER, Gerd Bruno , BOELKE, Tino Andreas
IPC分类号： A61M60/13 , A61M60/237 , A61M60/804 , A61M60/806 , A61M60/808
摘要： Aspects of the present technology relate to compressible and expandable pumps. In one aspect, a pump is provided including a pump housing that is expandable and compressible and a rotor that is expandable and compressible and disposed in the pump housing. The rotor includes at least one rotor blade, a hub, and an axis of rotation. At least a portion of the at least one rotor blade extends from the hub along a first axis that is offset a predetermined distance from a radial axis of the rotor that traverses the axis of rotation. The pump further includes a drive shaft having a proximal end and a distal end, wherein the hub of the rotor is mounted to the distal end of the drive shaft and the drive shaft is rotated to rotate the rotor.

7. 发明申请

WO2019137911A1 METHOD AND APPARATUS FOR CALIBRATION AND USE IN ESTIMATING BLOOD FLOW IN AN INTRAVASCULAR BLOOD PUMP 审中-公开
公开(公告)号：WO2019137911A1
公开(公告)日：2019-07-18
申请号：PCT/EP2019/050339
申请日：2019-01-08
申请人： ABIOMED EUROPE GMBH
发明人： SIESS, Thorsten , NIX, Christoph , BÖNSCH, Stefan
IPC分类号： A61M1/10 , A61M1/12
摘要： A method and an apparatus for use in estimating blood flow in an intravascular blood pump comprise retrieving reference data from a set of reference data obtained in a test environment. The set of reference data comprises, for at least one motor speed at different pump loads, including a first pump load, both a reference motor current (I) of a motor driving the blood pump and an amount of fluid flow through the blood pump. After placement of the blood pump in the patient, a patient-specific motor current for said motor speed at said first pump load is measured, and a motor current deviation value (ΔΙ) is calculated from the reference motor current (I) at said first pump load and patient-specific motor current. Finally, the motor current deviation value ΔΙ is used for estimating a patient-specific blood flow amount through the blood pump.

8. 发明申请

WO2019057636A1 BLOOD PUMP 审中-公开
公开(公告)号：WO2019057636A1
公开(公告)日：2019-03-28
申请号：PCT/EP2018/074929
申请日：2018-09-14
申请人： ABIOMED EUROPE GMBH
发明人： SIESS, Thorsten , KERKHOFFS, Wolfgang , SKRODSKY, Peter , WANG, Jimpo , GRAUWINKEL, Marius
IPC分类号： A61M1/10 , A61M1/12
摘要： An intravascular blood pump (1) comprises a pump casing (2) having a blood flow inlet (21) and a blood flow outlet (22), and an impeller (3) arranged in said pump casing (2) so as to be rotatable about an axis of rotation, wherein the impeller (3) has blades (31) sized and shaped for conveying blood from the blood flow inlet (21) to the blood flow outlet (22). The blood pump (1) further comprises a drive unit (104) for rotating the impeller (3), the drive unit (104) comprising a plurality of posts (140) arranged about the axis of rotation (10). Coil windings (47) around the posts are sequentially controllable so as to create a rotating magnetic field. The shaft portion (141) of each of the posts (140) comprises a soft magnetic material which is discontinuous in cross-section transverse to the longitudinal axis of the respective post (140).

9. 发明申请

WO2018036927A1 VENTRICULAR ASSIST DEVICE 审中-公开
标题翻译：心室辅助装置
公开(公告)号：WO2018036927A1
公开(公告)日：2018-03-01
申请号：PCT/EP2017/070953
申请日：2017-08-18
申请人： ABIOMED EUROPE GMBH
发明人： NIX, Christoph , LUNZE, Katrin , SIESS, Thorsten , ABOULHOSN, Walid
IPC分类号： A61M1/10
摘要： A control device (100) for controlling the rotational speed ( n VAD (t) ) of a non-pulsatile ventricular assist device, VAD, (50) uses an event-based within-a-beat control strategy, wherein the control device is configured to alter the rotational speed of the VAD within the cardiac cycle of the assisted heart and to synchronize the alteration of the rotational speed with the heartbeat by at least one sequence of trigger signals (σ(t)) that is related to at least one predetermined characteristic event in the cardiac cycle. Further, a VAD (50) for assistance of a heart comprises the control device (100) for controlling the VAD, wherein the VAD is preferably a non-pulsatile rotational, for example catheter-based, blood pump.
摘要翻译：控制装置（100）用于控制非旋转速度的转速（n VAD（t）），所述控制装置（100）脉搏式心室辅助装置VAD（50）使用基于事件的节拍内控制策略，其中该控制装置被配置为在辅助心脏的心动周期内改变VAD的旋转速度，并且同步通过与心动周期中的至少一个预定特征事件相关的至少一个触发信号序列（σ（t））来改变心率的旋转速度。此外，用于心脏辅助的VAD（50）包括用于控制VAD的控制装置（100），其中VAD优选是非脉动旋转的，例如基于导管的血泵。

10. 发明申请

WO2011039101A1 VERRIEGELBARE SCHNELLKUPPLUNG 审中-公开
标题翻译： LOCKABLE快速释放
公开(公告)号：WO2011039101A1
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064059
申请日：2010-09-23
申请人： ABIOMED EUROPE GMBH , SIESS, Thorsten , SPANIER, Gerd
发明人： SIESS, Thorsten , SPANIER, Gerd
IPC分类号： A61M39/10
CPC分类号： A61M39/1011 , A61M2039/1033 , A61M2039/1066
摘要： Eine einfach verriegelbare Schnellkupplung (10) zum lösbaren Verbinden eines Schlauchs (12) mit einem implantierbaren Apparat weist ein mit dem Schlauch (12) verbindbares, erstes Ansatzstück (14) und ein mit dem Apparat verbindbares zweites Ansatzstück (16) auf, wobei die Ansatzstücke (14, 16) im verriegelten Zustand gegeneinander verdrehbar sind.
摘要翻译：用于可拆卸地与可植入的装置连接的软管（12）一种容易可锁定的快速联接器（10）包括一个软管（12）可以被连接，所述第一端件（14）和一个连接到所述装置的第二端件（16），其中所述延伸件（14，16）是针对在锁定状态下彼此旋转。

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