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1. 发明申请

WO2019123171A1 ORAL COMPOSITIONS AND METHODS OF USE 审中-公开
公开(公告)号：WO2019123171A1
公开(公告)日：2019-06-27
申请号：PCT/IB2018/060108
申请日：2018-12-14
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： WLASCHIN, Katie F. , ENGLER, Amanda C. , COHEN, Hannah C. , WANG, Yizhong , GONG, Tao , TON, Tiffany T. , OXMAN, Joel D. , YANG, Jie
IPC分类号： A61K9/00 , A61K9/10 , A61K6/00 , A61K8/00 , A61K31/05 , A61K31/133 , A61K36/00 , A61K36/28 , A61P1/02
摘要： Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula based on the total weight of the composition HOCH 2 ―(CHOH) n ―CH 2 NR 1 R 2 wherein R 1 and R 2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R 3 , and SO 2 R 4 ; with R 3 and R 4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.

2. 发明申请

WO2016164316A1 REMOVABLE FILM FORMING GEL COMPOSITIONS AND METHODS FOR THEIR APPLICATION 审中-公开
标题翻译：可拆卸膜形成凝胶组合物及其应用方法
公开(公告)号：WO2016164316A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/025910
申请日：2016-04-04
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： LANGER-ANDERSON, Delony L. , GRIESGRABER, George W. , COLAK ATAN, Semra , PEREIRA, Junia , WLASCHIN, Katie F. , YOUNG, Alexi J. , ASMUS, Robert A. , KOHLER RIEDI, Petra L. , HAYS, David S. , RASMUSSEN, Jerald K. , SOLBERG, Michael J.
IPC分类号： C08L31/00
CPC分类号： A61L26/0066 , A61K9/7015 , A61K31/275 , A61K47/34 , A61L24/001 , A61L24/0015 , A61L24/043 , A61L24/06 , A61L26/00 , A61L26/0004 , A61L26/0019 , A61L26/0052 , A61L26/0061 , A61L26/0095 , A61L2300/404 , A61L2300/418 , A61L2400/04 , A61L2430/34 , Y02A50/473 , C08L83/04
摘要： Film forming gel compositions, useful in creating conformable and flexible gel bandages, can be formulate from a film forming polymer, a tackifier, and a volatile solvent. The film forming gels can also include antiseptics, cationic polymer coagulants, fillers, and other additives. The gel compositions form relatively thick films when dried on tissue, and can exhibit enhanced breathability to promote wound healing.
摘要翻译：可用于形成适形和柔性凝胶绷带的成膜凝胶组合物可以由成膜聚合物，增粘剂和挥发性溶剂配制。成膜凝胶也可以包括防腐剂，阳离子聚合物凝结剂，填料和其它添加剂。凝胶组合物在组织上干燥时形成相对厚的膜，并且可以表现出增强的透气性以促进伤口愈合。

3. 发明申请

WO2010129795A1 ORAL CARE METHOD AND KIT 审中-公开
标题翻译：口腔护理方法和包装
公开(公告)号：WO2010129795A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/033902
申请日：2010-05-06
申请人： 3M INNOVATIVE PROPERTIES COMPANY , WLASCHIN, Katie F. , DOMBROWSKI, Alan R. , SCHOLZ, Matthew T. , PARTHASARATHY, Ranjani V.
发明人： WLASCHIN, Katie F. , DOMBROWSKI, Alan R. , SCHOLZ, Matthew T. , PARTHASARATHY, Ranjani V.
IPC分类号： A61K31/155 , A61P17/00
CPC分类号： A61K31/155 , A61M16/04
摘要： A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue; wherein the mammalian tissue is oral tissue of a subject; wherein the multi-valent cationic antiseptic is other than a metal ion; and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and/or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 10 6 cfu of Pseudomonas auerginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B; an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition; and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.
摘要翻译：一种在哺乳动物组织非殖化时保湿的方法，该方法包括将多价阳离子防腐组合物施用于组织，以及将保湿组合物施用于相同组织的至少一部分; 其中哺乳动物组织是受试者的口腔组织; 其中所述多价阳离子防腐剂不是金属离子; 并且其中当根据测试方法F测试时，所施加的组合物基本上排除任何与多价阳离子防腐组合物中包含的多价阳离子防腐剂组合时引起沉淀的组分，和/或其中所述保湿组合物使得当将106cfu的绿脓假单胞菌与1.1g的保湿组合物和1.5g多价阳离子防腐组合物混合在一起时，提供至少为2的活细菌细胞数目的对数减少，其中含有0.12重量％根据测试方法B的阳离子抗菌剂; 口腔护理套件，其包含包含所述多价阳离子防腐剂和所述保湿组合物的组合物; 提供了使用保湿组合物和使用阳离子防腐剂涂布或浸渍的气管内导管的需要插管的患者的口腔组织的保湿方法。

4. 发明申请

WO2020234811A1 ORAL COMPOSITIONS AND METHODS OF USE 审中-公开
公开(公告)号：WO2020234811A1
公开(公告)日：2020-11-26
申请号：PCT/IB2020/054805
申请日：2020-05-20
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RUSIN, Richard P. , YANG, Jie , KOHLER RIEDI, Petra , CONNELL, Jodi L. , HAEBERLEIN, Ingo , WLASCHIN, Katie F. , COHEN, Hannah C. , TON, Tiffany T. , KLAIBER, Paul R. , WANG, Yizhong , OXMAN, Joel D.
IPC分类号： A61K8/44 , A61K8/60 , A61Q11/00
摘要： A composition comprising: from 0.2 wt-% to 3 wt-% total of arginine, glycine, or a combination thereof based on the total weight of the composition; and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula I: HOCH 2 -(CHOH) n -CH 2 NR 1 R 2 (I) wherein R 1 and R 2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R 3 , and SO2R 4 ; with R 3 and R 4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5.

5. 发明申请

WO2020136606A1 ORAL ARTICLES AND METHODS OF USE 审中-公开
公开(公告)号：WO2020136606A1
公开(公告)日：2020-07-02
申请号：PCT/IB2019/061380
申请日：2019-12-26
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： ENGLER, Amanda C. , WLASCHIN, Katie F. , COHEN, Hannah C. , WANG, Yizhong , TON, Tiffany T. , YANG, Jie , OXMAN, Joel D. , WOLLMUTH, Emily M.
IPC分类号： A61K8/02 , A61K8/34 , A61K8/36 , A61K8/73 , A61K8/92 , A61P1/02 , A61Q11/00 , A61K9/00 , A61K9/70
摘要： Articles that include from 20 wt-% to 45 wt-% of one or more plant based oils based on the total weight of the article; from 50 wt-% to 70 wt-% of one or more polymer film formers based on the total weight of the article; and from 5 wt-% to 15 wt-% of one or more humectants based on the total weight of the article. Further articles comprises this combination of oil, film former and humectant as a first layer adjacent to which a second layer comprises a mucoadhesive polymer. The articles may be used to prevent formation or maintenance of biofilm in an oral tissue, affect hydration loss in an oral tissue, affect lubricity or lubriciousness in an oral tissue or treat xerostomia or dry mouth. Preferred polymer film formers include pullulan, xanthan gum, HP guar, ethyl cellulose and carrageenan.

6. 发明申请

WO2019123261A3 ORAL COMPOSITIONS AND METHODS OF USE 审中-公开
公开(公告)号：WO2019123261A3
公开(公告)日：2019-06-27
申请号：PCT/IB2018/060270
申请日：2018-12-18
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： WLASCHIN, Katie F. , ENGLER, Amanda C. , COHEN, Hannah C. , WANG, Yizhong , GONG, Tao , TON, Tiffany , OXMAN, Joel D. , YANG, Jie
IPC分类号： A61K8/92 , A61Q11/00 , A61K36/00 , A61K9/00 , A61K47/44 , A61K8/41 , A61K8/42 , A61K8/44 , A61P1/02
摘要： Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

7. 发明申请

WO2014035981A1 CHLORHEXIDINE GLUCONATE COMPOSITIONS, RESIN SYSTEMS AND ARTICLES 审中-公开
标题翻译：氯林酮葡萄糖酸酯组合物，树脂体系和文章
公开(公告)号：WO2014035981A1
公开(公告)日：2014-03-06
申请号：PCT/US2013/056823
申请日：2013-08-27
申请人： 3M INNOVATIVE PROPERTIES COMPANY , MENON, Vinod P. , RULE, Joseph D. , ROSS, Richard B. , CONRAD-VLASAK, Deena M. , WLASCHIN, Katie F.
发明人： MENON, Vinod P. , RULE, Joseph D. , ROSS, Richard B. , CONRAD-VLASAK, Deena M. , WLASCHIN, Katie F.
IPC分类号： A61L31/16 , A61L15/44 , A61L15/46 , A61L15/58
CPC分类号： A61L31/16 , A61L15/44 , A61L15/46 , A61L15/58 , A61L31/14 , A61L2300/206 , A61L2300/404
摘要： Compositions containing chlorhexidine gluconate solubilized in hydrophobic vehicles are described. Resin systems containing such chlorhexidine gluconate compositions, including adhesives and articles incorporating such resin systems, including medical articles such as drapes are also described.
摘要翻译：描述了含有溶解在疏水载体中的葡聚糖氯己定的组合物。还描述了含有这种葡萄糖酸组合物的树脂体系，包括粘合剂和掺入这种树脂体系的制品，包括医疗制品如窗帘。

8. 发明申请

WO2021038529A1 TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS 审中-公开
公开(公告)号：WO2021038529A1
公开(公告)日：2021-03-04
申请号：PCT/IB2020/058075
申请日：2020-08-28
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： LANDGREBE, Kevin D. , PARTHASARATHY, Ranjani V. , WLASCHIN, Katie F.
IPC分类号： A61K31/79 , A61K9/00 , A61K33/18 , A61P31/16
摘要： Aspects of the present disclosure relate to a method of using an antiseptic composition or a pharmaceutically acceptable salt thereof comprising between 3.5 and 10.5 weight percent, inclusive, iodophor as a prophylaxis against influenza. The method includes applying the antiseptic composition to a mucosal tissue of a mammalian subject according to a treatment plan.

9. 发明申请

WO2020234744A1 ORAL COMPOSITIONS AND METHODS OF USE 审中-公开
公开(公告)号：WO2020234744A1
公开(公告)日：2020-11-26
申请号：PCT/IB2020/054685
申请日：2020-05-18
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： RUSIN, Richard P. , YANG, Jie , KOHLER RIEDI, Petra L. , CONNELL, Jodi L. , HAEBERLEIN, Ingo R. , COHEN, Hannah C. , WLASCHIN, Katie F. , KLAIBER, Paul R. , WANG, Yizhong , OXMAN, Joel D. , TON, Tiffany T. , BOEHMER, Roxanne A.
IPC分类号： A61Q11/00 , A61K8/41 , A61K8/60
摘要： A composition comprising from 1 wt-% to 3 wt-% total of glucosamine a derivative of glucosamine, or a combination thereof based on the total weight of the composition, and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula (I) : ΗΟCΗ 2 -(ΟΗΟΗ) n -CΗ 2 ΝR 1 R 2 (I) wherein R 1 and R 2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R 3 and SO 2 R 4 with R 3 and R 4 being independently selected from the group consisting of an alkyl group, an aryl group and an aralkyl group, wherein n is an integer from 2 to 5.

10. 发明申请

WO2020136604A2 ORAL ARTICLES AND METHODS OF USE 审中-公开
公开(公告)号：WO2020136604A2
公开(公告)日：2020-07-02
申请号：PCT/IB2019/061378
申请日：2019-12-26
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： COHEN, Hannah C , WLASCHIN, Katie F. , WANG, Yizhong , ENGLER, Amanda C. , YANG, Jie , TON, Tiffany T. , OXMAN, Joel D.
IPC分类号： A61K9/00 , A61K31/00 , A61K47/12 , A61K47/36 , A61K47/44
摘要： Articles that include not greater than 60 wt-% of one or more plant based oil that is solid at 25 ° C (room temperature), the weight percent based on the total weight of the article; and from 4 wt-% to 10 wt-% of gelatin, from 0.8 to 5 wt-% of agar, or a combination thereof, the weight percent based on the total weight of the article, wherein the article is solid set and homogeneous. Methods of using the articles and compositions for forming the articles are also disclosed.

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