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1. 发明申请

WO2006086449A3 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 审中-公开
标题翻译：烷基取代的二氮杂环戊二烯和噻唑啉
公开(公告)号：WO2006086449A3
公开(公告)日：2007-07-05
申请号：PCT/US2006004391
申请日：2006-02-08
申请人： 3M INNOVATIVE PROPERTIES CO , PRINCE RYAN B , MERRILL BRYON A , HEPPNER PHILIP D , KSHIRSAGAR TUSHAR A , WURST JOSHUA R , MANSKE KARL J , RICE MICHAEL J
发明人： PRINCE RYAN B , MERRILL BRYON A , HEPPNER PHILIP D , KSHIRSAGAR TUSHAR A , WURST JOSHUA R , MANSKE KARL J , RICE MICHAEL J
IPC分类号： C07D513/04 , A61K31/4365
CPC分类号： C07D513/04 , C07D519/00
摘要： Thiazoloquinolines and thiazolonaphthyridines with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
摘要翻译：含有这些化合物的化合物，中间体，制备方法和这些化合物作为免疫调节剂的使用方法的6,7,8或9位具有烷氧基取代基的噻唑并喹啉和噻唑并萘啶在动物中诱导细胞因子生物合成公开了包括病毒和肿瘤疾病在内的疾病的治疗。

2. 发明申请

WO2006107753A2 PYRAZOLOPYRIDINES AND ANALOGS THEREOF 审中-公开
标题翻译：吡咯并吡啶及其类似物
公开(公告)号：WO2006107753A2
公开(公告)日：2006-10-12
申请号：PCT/US2006011953
申请日：2006-03-31
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： HAYS DAVID S , DANIELSON MICHAEL E , GERSTER JOHN F , NIWAS SHRI , PRINCE RYAN B , KSHIRSAGAR TUSHAR A , HEPPNER PHILIP D , MOSER WILLIAM H , MOSEMAN JOAN T , RADMER MATTHEW R , KAVANAGH MAUREEN A , STRONG SARAH A , BONK JASON D
IPC分类号： C07D471/02 , A61K31/4745
CPC分类号： C07D471/04 , C07D471/14
摘要： Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, and prodrugs thereof, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
摘要翻译：吡唑并吡啶-4-胺，吡唑啉-4-胺，吡唑啉-4-基胺，6,7,8,9-四氢吡唑并喹啉-4-胺及其前药，含有这些化合物的药物组合物，中间体，制备方法和方法这些化合物作为免疫调节剂的用途，用于诱导或抑制动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。

3. 发明申请

WO2014168825A3 COATING SYSTEM AND METHOD 审中-公开
标题翻译：涂层系统和方法
公开(公告)号：WO2014168825A3
公开(公告)日：2014-12-24
申请号：PCT/US2014032958
申请日：2014-04-04
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： JONES CLINTON L , SWEENEY SHAWN R , FABOZZI SCOTT M , APEL CORI S , PRINCE RYAN B , MACCALLUM CARSON
IPC分类号： B05C7/08 , B29B7/74
CPC分类号： B05B13/06 , B05B7/32 , B05B12/1418 , B05C7/08 , B05D1/02 , F16L58/1027
摘要： A portable delivery system for delivering a multiple part coating composition for in situ coating an internal pipeline surface comprises a housing including a controller, at least two composition containers, a first hose, a hose delivery system, a pump, and at least two mass flow meters. The composition containers contain differing compositions, and each container includes a composition depth monitoring apparatus. The first hose comprises at least two additional hoses, where two of the additional hoses each deliver one of the compositions to a composition applicator. The hose delivery system stores and delivers the first hose to the pipeline, and the pump is coupled to the composition containers and the first hose. The mass flow meters are each coupled to a pump outlet corresponding to an outlet of the respective first or second composition container.
摘要翻译：用于递送用于原位涂覆内部管道表面的多部分涂料组合物的便携式递送系统包括外壳，所述外壳包括控制器，至少两个组合物容器，第一软管，软管递送系统，泵以及至少两个质量流量米。组合物容器包含不同的组合物，并且每个容器包括组合物深度监测装置。第一软管包括至少两个额外的软管，其中两个另外的软管各自将组合物中的一种递送至组合物施用器。软管输送系统将第一软管储存并输送到管道，并且将泵连接到组合物容器和第一软管。质量流量计各自连接到对应于相应的第一或第二组合物容器的出口的泵出口。

4. 发明申请

WO2004058759A8 ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES 审中-公开
标题翻译： ARYL / HETARYL取代的咪唑啉
公开(公告)号：WO2004058759A8
公开(公告)日：2005-03-17
申请号：PCT/US0340373
申请日：2003-12-18
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： HAYS DAVID S , NIWAS SHRI , KSHIRSAGAR TUSHAR , GHOSH TARUN K , GUPTA SHALLEY K , HEPPNER PHILIP D , MERRILL BRYON A , BONK JASON D , DANIELSON MICHAEL E , GERSTER JOHN F , HARALDSON CHAD A , JOHANNESSEN SARAH C , KAVANAGH MAUREEN A , LINDSTROM KYLE J , PRINCE RYAN B , RADMER MATTHEW R , RICE MICHAEL J , SQUIRE DAVID J , STRONG SARAH A , WURST JOSHUA R
IPC分类号： A61P35/00 , C07D471/04 , A61K31/437
CPC分类号： C07D471/04
摘要： Aryl substituted imidazoquinoline compounds, according to formula I, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing w or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral., and neoplastic, are disclosed. formula (I): wherein: R is selected from the group consisting of alkyl, alkoxy, hydroxy, and trifluoromethyl;. N is 0 or 1; R3 is selected from the group consisting of: -Z-Ar,-Z-Ar'-Y-R4, -Z-Ar'-X-Y-R4, Z-Ar'-R5, and-Z-Ar'-X-R5; Ar is selected from the group consisting of aryl and heteroaryl both of which can be unsubstituted or can be substituted by one or more substituents independently selected from the group consisting of alkyl, alkenyl, alkoxy, methylenedioxy, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, hydroxyalkyl, mercapto, cyano, carboxy, formyl, aryl, aryloxy, arylalkoxy, heteroaryl, heteroaryloxy, heteroarylalkoxy; heterocyctyl, heterocyclylalkyl, amino, alkylamino, and dialkylamino.
摘要翻译：根据式I的芳基取代的咪唑并喹啉化合物，含有这些化合物的化合物，中间体和使用这些化合物作为免疫调节剂的药物组合物，用于在动物中诱导w或抑制细胞因子生物合成以及治疗包括病毒和肿瘤的疾病，被披露。式（I）：其中：R选自烷基，烷氧基，羟基和三氟甲基。 N为0或1; R3选自：-Z-Ar，-Z-Ar'-Y-R4，-Z-Ar'-XY-R4，Z-Ar'-R5和-Z-Ar'-X- R5; Ar选自芳基和杂芳基，它们都可以是未取代的或可以被一个或多个独立地选自烷基，烯基，烷氧基，亚甲二氧基，卤代烷基，卤代烷氧基，卤素，硝基，羟基羟基烷基，巯基，氰基，羧基，甲酰基，芳基，芳氧基，芳基烷氧基，杂芳基，杂芳氧基，杂芳基烷氧基; 杂环基，杂环基烷基，氨基，烷基氨基和二烷基氨基。

5. 发明申请

WO2009158179A3 APPLICATOR TOOL 审中-公开
标题翻译：申请人工具
公开(公告)号：WO2009158179A3
公开(公告)日：2010-04-15
申请号：PCT/US2009046563
申请日：2009-06-08
申请人： 3M INNOVATIVE PROPERTIES CO
发明人： DYER JOHN J , HAAK CHRISTOPHER A , PRINCE RYAN B
IPC分类号： B25B27/00 , B05C5/00 , B25B27/02 , B25B33/00
CPC分类号： B25B27/0092 , Y10T156/10 , Y10T156/1788
摘要： A tool for applying an elongate adhesive attachment article to a window assembly including a window film and window frame includes a body having a contact surface for guiding the tool along the substrate, a positioner arranged to align the adhesive article on the window assembly, and a force applier configured to apply a force to the attachment article in the direction of the window assembly. A method of securing a window film to a window frame using such a tool is also provided.
摘要翻译：用于将细长的粘合剂附着制品应用于包括窗膜和窗框的窗组件的工具包括：主体，其具有用于沿着基板引导工具的接触表面;布置成将粘合剂制品对准在窗组件上的定位器，施力器构造成在窗组件的方向上向附件施加力。还提供了使用这种工具将窗膜固定到窗框的方法。

6. 发明申请

WO2006093514A3 ARYL AND ARYLALKYLENYL SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 审中-公开
标题翻译：亚芳基和亚苄基取代的噻唑啉和噻唑啉
公开(公告)号：WO2006093514A3
公开(公告)日：2007-07-12
申请号：PCT/US2005021334
申请日：2005-06-17
申请人： 3M INNOVATIVE PROPERTIES CO , PRINCE RYAN B , MERRILL BRYON A , KSHIRSAGAR TUSHAR A , HEPPNER PHILIP D , LUNDQUIST GREGORY D JR
发明人： PRINCE RYAN B , MERRILL BRYON A , KSHIRSAGAR TUSHAR A , HEPPNER PHILIP D , LUNDQUIST GREGORY D JR
IPC分类号： C07D471/14 , A61K31/437
CPC分类号： C07D513/04
摘要： Thiazoloquinoline and thiazolonaphthyridine compounds having an aryl or arylalkylenyl substituent at the 6-, 7-, 8-, or 9-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals 10 and in the treatment of diseases including viral and neoplastic diseases are disclosed.
摘要翻译：在6-，7-，8-或9-位具有芳基或芳基亚烷基取代基的噻唑并喹啉和噻唑并吡啶化合物，其含有化合物，中间体和制备方法以及这些化合物作为免疫调节剂的使用方法，用于调节公开了动物10中的细胞因子生物合成和包括病毒和肿瘤疾病在内的疾病的治疗。

7. 发明申请

WO2005079195A2 PYRAZOLOPYRIDINES AND ANALOGS THEREOF 审中-公开
标题翻译：吡咯并吡啶及其类似物
公开(公告)号：WO2005079195A2
公开(公告)日：2005-09-01
申请号：PCT/US2004032480
申请日：2004-10-01
申请人： 3M INNOVATIVE PROPERTIES CO , HAYS DAVID S , DANIELSON MICHAEL E , GERSTER JOHN F , NIWAS SHRI , PRINCE RYAN B , KSHIRSAGAR TUSHAR A , HEPPNER PHILIP D , MOSER WILLIAM H , MOSEMAN JOAN T , RADMER MATTHEW R , KAVANAGH MAUREEN A , STRONG SARAH A , BONK JASON D
发明人： HAYS DAVID S , DANIELSON MICHAEL E , GERSTER JOHN F , NIWAS SHRI , PRINCE RYAN B , KSHIRSAGAR TUSHAR A , HEPPNER PHILIP D , MOSER WILLIAM H , MOSEMAN JOAN T , RADMER MATTHEW R , KAVANAGH MAUREEN A , STRONG SARAH A , BONK JASON D
IPC分类号： C07D471/04 , C07D471/14
CPC分类号： C07D471/04 , C07D401/14 , C07D471/14 , C07D495/14
摘要： Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
摘要翻译：吡唑并吡啶-4-胺，吡唑啉-4-胺和6,7,8,9-四氢吡唑并喹啉-4-胺，含有这些化合物的化合物，中间体和使用方法作为免疫调节剂的药物组合物，用于诱导或抑制动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。

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