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    • 3. 发明申请
    • 消化管運動促進飲食物
    • 刺激性移动运动的重塑
    • WO2004002978A1
    • 2004-01-08
    • PCT/JP2003/008081
    • 2003-06-26
    • サントリー株式会社諏訪 芳秀藤居 亙堀 妃佐子横尾 芳明糠谷 東雄辻 邦郎
    • 諏訪 芳秀藤居 亙堀 妃佐子横尾 芳明糠谷 東雄辻 邦郎
    • C07D307/84
    • C07D307/84A23L33/105A61K31/343
    • A substance capable of stimulating the movement of digestive tract, comprising a compound of the formula: (I) (active substance alpha and active substance beta being stereoisomers), which substance is derived from natural products and hence causes no side effects, is highly safe even when continuously used for a prolonged period of time and can be widely employed as additives to refreshments, etc.; and a refreshment containing an additive comprising the stimulating substance. In particular, a digestive tract movement stimulating substance capable of acting on muscarine M3 receptor, obtained from beer through isolation and purification, which substance is one having drinkability stimulating effect; and a composition from natural products or natural processed products, comprising the above substance. The thus provided substance or composition is used as an additive to refreshment, thereby providing a refreshment capable of stimulating the movement of digestive tract.
    • 能够刺激消化道运动的物质,其包含下列化合物:(I)(活性物质α和活性物质β为立体异构体),该物质衍生自天然产物,因此不产生副作用,是高度安全的 即使连续使用较长时间,也可广泛用作茶点等添加剂; 以及含有包含刺激物质的添加剂的茶点。 特别是能够通过分离和纯化从啤酒获得的能够作用于毒蕈碱M3受体的消化道运动刺激物质,其具有可饮用性刺激作用; 以及包含上述物质的天然产物或天然加工产品的组合物。 因此提供的物质或组合物用作茶点的添加剂,从而提供能够刺激消化道运动的茶点。