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1. 发明申请

WO2007028157A1 SYSTEMS, APPARATUS AND METHODS FOR VACUUM FILTRATION 审中-公开
标题翻译：用于真空过滤的系统，装置和方法
公开(公告)号：WO2007028157A1
公开(公告)日：2007-03-08
申请号：PCT/US2006/034560
申请日：2006-09-05
申请人： ZUK, Peter, Jr.
发明人： ZUK, Peter, Jr.
IPC分类号： B01L3/00 , G01N1/28
CPC分类号： G01N1/4077 , B01D29/085 , B01D2201/204 , B01L3/563 , G01N2035/1053
摘要： A liquid filtering system (100) and methods for filtering are disclosed. One embodiment of the system includes a filtering apparatus (100a) having a receiving receptacle (50) coupled with an (30) adapter. The adapter has an adapter port (34) for receiving a vacuum and an interface for coupling with an output receptacle (80) that receives filtered liquid from the filtering apparatus. The adapter (30) is between the receiving receptacle (50) and output receptacle (80) when the output receptacle is coupled with the adapter interface. The system also includes a base (1) having a substantially rigid housing containing an internal vacuum channel (2) terminating at a base vacuum delivery port (2a). The adapter is couplable with the base to connect the adapter port to the base vacuum delivery port.
摘要翻译：公开了一种液体过滤系统（100）和过滤方法。该系统的一个实施例包括具有与（30）适配器耦合的接收容器（50）的过滤装置（100a）。适配器具有用于接收真空的适配器端口（34）和用于与从过滤装置接收过滤液体的输出插座（80）耦合的接口。当输出插座与适配器接口耦合时，适配器（30）在接收插座（50）和输出插座（80）之间。该系统还包括具有基本上刚性的壳体的底座（1），其包含终止于基部真空输送口（2a）的内部真空通道（2）。适配器可与基座连接，以将适配器端口连接到基本真空输送端口。

2. 发明申请

WO2008103142A1 A HIGH CAPACITY BIOLOGICAL FLUID FILTRATION APPARATUS 审中-公开
标题翻译：高容量生物流体过滤装置
公开(公告)号：WO2008103142A1
公开(公告)日：2008-08-28
申请号：PCT/US2007/004661
申请日：2007-02-22
申请人： HEMERUS MEDICAL, LLC , ZUK, Peter Jr.
发明人： ZUK, Peter Jr.
IPC分类号： B01D11/00 , B01D61/00 , C02F1/44
CPC分类号： A61M1/3633 , A61M1/0209 , A61M1/0218 , A61M1/3635 , B01D2323/42
摘要： A biological fluid filtration device, system, and method, for filtering a biological fluid, the device comprising a housing having an inlet, a first outlet and a second outlet, with a first fluid flow path defined between the inlet and the first outlet, with a second fluid flow path defined between the inlet and the second outlet, with a first biological fluid filtration media interposed between the inlet and the first outlet and across the first fluid flow path, with a second biological fluid filtration media interposed between the inlet and the second outlet and across the second fluid flow path, the housing essentially lacking a solid partition wall between the first biological fluid filtration media and the second biological fluid filtration media, a first flow restriction may be added downstream of the first biological fluid filtration media, and a second flow restriction may be added downstream of the second biological fluid filtration media, in another embodiment, the device comprises a housing having an inlet an outlet with a flow path defined between the inlet and the outlet, with a biological fluid filtration media interposed between the inlet and the outlet and across the fluid flow path, the device further including a flow restriction downstream of the biological fluid filtration media.
摘要翻译：一种用于过滤生物流体的生物流体过滤装置，系统和方法，所述装置包括具有入口，第一出口和第二出口的壳体，所述第一流体流动路径限定在所述入口和所述第一出口之间，限定在所述入口和所述第二出口之间的第二流体流动路径，其中介于所述入口和所述第一出口之间并跨越所述第一流体流动路径的第一生物流体过滤介质，所述第二生物流体过滤介质介于所述入口和所述第二出口之间，第二出口并穿过第二流体流动路径，壳体基本上在第一生物流体过滤介质和第二生物流体过滤介质之间缺少固体分隔壁，第一流动限制可以被添加到第一生物流体过滤介质的下游，以及在另一个实施方案中，第二生物流体过滤介质的下游可以添加第二流量限制将具有入口的入口设置为具有限定在入口和出口之间的流动路径的外壳的壳体，其中插入在入口和出口之间并跨越流体流动路径的生物流体过滤介质，该装置还包括在生物流体过滤介质。

3. 发明申请

WO2005023395A1 A BIOLOGICAL FLUID FILTRATION APPARATUS 审中-公开
标题翻译：生物流体过滤装置
公开(公告)号：WO2005023395A1
公开(公告)日：2005-03-17
申请号：PCT/US2004/029026
申请日：2004-09-07
申请人： ZUK, Peter, Jr.
发明人： ZUK, Peter, Jr.
IPC分类号： B01D37/00
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/0231 , A61M1/3633 , B01D69/06 , B01D69/10
摘要： Biological fluid filtration systems (3000) include biological fluid filtration devices (1500) capable of filtering blood or blood products, including the removal of leukocytes from the blood or blood product. Each system (3000) includes a means (1440) to automatically drain the biological fluid upstream of the biological fluid filtration media disposed in the biological fluid filtration device (1500). Both single sided and double sided biological fluid filtration devices (1500) are disclosed, independent fluid flow path on one side of the partition wall, and a second independent fluid flow path on the other side of the partition wall. Draining means include vent filtration devices (1440), diaphragm draining devices, and biological fluid filtration devices (1500) that include an integral diaphragm. The biological fluid filtration devices (1500) include low hold-up volume filter underdrains that purge in excess of 95% of the initial air in the device before liquid begins to flow from the outlet, thereby allowing the devices (1500) to be used in bed side applications. Variable surface area biological fluid filtration devices (1500) are disclosed that further reduce hold-up volume.
摘要翻译：生物流体过滤系统（3000）包括能够过滤血液或血液制品的生物流体过滤装置（1500），包括从血液或血液制品中除去白细胞。每个系统（3000）包括用于自动排出设置在生物流体过滤装置（1500）中的生物流体过滤介质上游的生物流体的装置（1440）。公开了单面和双面生物流体过滤装置（1500），分隔壁一侧上的独立流体流动路径和分隔壁另一侧上的第二独立流体流动路径。排水装置包括排气过滤装置（1440），隔膜排放装置和包括整体隔膜的生物流体过滤装置（1500）。生物流体过滤装置（1500）包括低的滞留体积过滤器下水排泄物，其在液体开始从出口流出之前吹扫装置中初始空气的95％以上，从而允许将装置（1500）用于床边应用。公开了可变表面积生物流体过滤装置（1500），其进一步减少了保持体积。

4. 发明申请

WO2008144083A1 METHODS AND APPARATUS FOR FOAM CONTROL IN A VACUUM FILTRATION SYSTEM 审中-公开
标题翻译：在真空过滤系统中的泡沫控制的方法和装置
公开(公告)号：WO2008144083A1
公开(公告)日：2008-11-27
申请号：PCT/US2008/052642
申请日：2008-01-31
申请人： NYPRO INC. , KANE, Jeffrey, F. , TAYLOR, Thomas , ZUK, Peter, Jr. , PHILLIPS, Sean, Landis
发明人： KANE, Jeffrey, F. , TAYLOR, Thomas , ZUK, Peter, Jr. , PHILLIPS, Sean, Landis
IPC分类号： B01D29/05 , G01N1/28
CPC分类号： B01D29/05 , B01D29/085 , B01D29/925 , B01D29/965 , B01D2201/204 , B01L3/502 , B01L2300/0681 , B01L2400/049 , G01N1/4077 , G01N2001/4088
摘要： A flow diverter, vacuum control and tilting of the liquid filtering system are used alternatively or in conjunction to reduce foam production in a filtered liquid sample. A liquid filtering system (20) includes an upper sample reservoir (21), a filter (22) and a lower storage bottle (23). A vacuum is applied below the sample filter to draw sample liquid through the sample filter (22) into the storage bottle (23). A flow diverter may be used to direct flow of the filtered liquid sample onto a sidewall of the storage bottle or guide flow to a bottom of the storage bottle. The vacuum may be regulated to reduce foaming. The liquid filtering system may be tilted to direct fluid to the sidewall of the lower storage bottle and reduce foaming.
摘要翻译：替代地或结合使用液体过滤系统的分流器，真空控制和倾斜来减少过滤的液体样品中的泡沫产生。液体过滤系统（20）包括上部样品贮存器（21），过滤器（22）和下部储存瓶（23）。在样品过滤器下方施加真空以将样品液体通过样品过滤器（22）抽入储存瓶（23）中。流量分流器可以用于将过滤的液体样品的流动引导到存储瓶的侧壁或引导流到存储瓶的底部。可以调节真空以减少起泡。液体过滤系统可以倾斜以将流体引导到下储存瓶的侧壁并减少发泡。

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