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1. 发明申请

WO2014144100A3 SGC STIMULATORS 审中-公开
标题翻译： SGC刺激者
公开(公告)号：WO2014144100A3
公开(公告)日：2014-11-06
申请号：PCT/US2014028370
申请日：2014-03-14
申请人： NAKAI TAKASHI , MOORE JOEL , PERL NICHOLAS ROBERT , IYENGAR RAJESH R , MERMERIAN ARA , IM G-YOON JAMIE , LEE THOMAS WAI-HO , HUDSON COLLEEN , RENNIE GLEN ROBERT , JIA JAMES , RENHOWE PAUL ALLEN , BARDEN TIMOTHY CLAUDE , YU XIANG Y , SHEPPECK JAMES EDWARD , IYER KARTHIK , JUNG JOON
发明人： NAKAI TAKASHI , MOORE JOEL , PERL NICHOLAS ROBERT , IYENGAR RAJESH R , MERMERIAN ARA , IM G-YOON JAMIE , LEE THOMAS WAI-HO , HUDSON COLLEEN , RENNIE GLEN ROBERT , JIA JAMES , RENHOWE PAUL ALLEN , BARDEN TIMOTHY CLAUDE , YU XIANG Y , SHEPPECK JAMES EDWARD , IYER KARTHIK , JUNG JOON
IPC分类号： C07D413/14 , A61K31/506 , A61P3/00 , A61P9/00 , A61P15/00 , A61P25/00 , C07D403/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D495/04
CPC分类号： A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K45/06 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D451/02 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/107 , C07D495/04 , C07D498/04
摘要： Compounds of Formulae (I') and (I) are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
摘要翻译：描述了式（I'）和（I）的化合物，其可用作sGC的刺激剂，特别是NO-非依赖性血红素依赖性刺激物。这些化合物也可用于治疗，预防或治疗本文公开的各种疾病。

2. 发明申请

WO2014144100A2 SGC STIMULATORS 审中-公开
标题翻译： SGC刺激剂
公开(公告)号：WO2014144100A2
公开(公告)日：2014-09-18
申请号：PCT/US2014/028370
申请日：2014-03-14
申请人： NAKAI, Takashi , MOORE, Joel , PERL, Nicholas Robert , IYENGAR, Rajesh R. , MERMERIAN, Ara , IM, G-Yoon Jamie , LEE, Thomas Wai-Ho , HUDSON, Colleen , RENNIE, Glen Robert , JIA, James , RENHOWE, Paul Allen , BARDEN, Timothy Claude , YU, Xiang Y , SHEPPECK, James Edward , IYER, Karthik , JUNG, Joon
发明人： NAKAI, Takashi , MOORE, Joel , PERL, Nicholas Robert , IYENGAR, Rajesh R. , MERMERIAN, Ara , IM, G-Yoon Jamie , LEE, Thomas Wai-Ho , HUDSON, Colleen , RENNIE, Glen Robert , JIA, James , RENHOWE, Paul Allen , BARDEN, Timothy Claude , YU, Xiang Y , SHEPPECK, James Edward , IYER, Karthik , JUNG, Joon
IPC分类号： C07D413/14
CPC分类号： A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K45/06 , C07D401/14 , C07D403/04 , C07D413/14 , C07D417/14 , C07D451/02 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10 , C07D491/107 , C07D495/04 , C07D498/04
摘要： Compounds of Formulae (I') and (I) are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
摘要翻译：描述了式（I'）和（I）的化合物，其可用作sGC的刺激物，特别是不依赖NO的血红素依赖性刺激物。这些化合物也可用于治疗，预防或管理本文公开的各种病症。

3. 发明申请

WO2013053070A1 HEAT TOLERANCE MICRORNA 审中-公开
标题翻译：耐热微波炉
公开(公告)号：WO2013053070A1
公开(公告)日：2013-04-18
申请号：PCT/CN2011/001685
申请日：2011-10-09
申请人： SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CAS , KEYGENE N.V. , HE, Yuke , PRINS, Marcel , YU, Xiang
发明人： HE, Yuke , PRINS, Marcel , YU, Xiang
IPC分类号： C12N15/82 , C12N15/113 , C12N15/67 , A01H1/00
CPC分类号： C12N15/8271 , C12N15/113 , C12N15/8218 , C12N15/8273 , C12N2310/141
摘要： The involvement of a known miRNA and its target in the heat stress response of plants is provided. Downregulation of said miRNA, upregulation of its target, reducing or eliminating binding of said miRNA to its target, and/or reducing or eliminating cleavage of said target by said miRNA provide strategies to improve heat tolerance in said plants. Also provided are strategies to downregulate said miRNA, upregulate said target, reduce or eliminate binding of said miRNA to its target and/or cleavage of said target by said miRNA.
摘要翻译：提供已知的miRNA及其靶标参与植物的热应激反应。所述miRNA的下调，其靶标的上调，减少或消除所述miRNA与其靶标的结合，和/或减少或消除所述miRNA对所述靶标的切割提供了改善所述植物耐热性的策略。还提供了下调所述miRNA，上调靶标，降低或消除所述miRNA与其靶标的结合和/或所述miRNA切割所述靶标的策略。

4. 发明申请

WO2013053069A1 HEAT TOLERANCE MICRORNA 审中-公开
标题翻译：耐热微波炉
公开(公告)号：WO2013053069A1
公开(公告)日：2013-04-18
申请号：PCT/CN2011/001684
申请日：2011-10-09
申请人： SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CAS , KEYGENE N.V. , HE, Yuke , PRINS, Marcel , YU, Xiang
发明人： HE, Yuke , PRINS, Marcel , YU, Xiang
IPC分类号： C12N15/113 , C12N15/82 , A01H1/00
CPC分类号： C12N15/8218 , C12N15/113 , C12N15/8271 , C12N15/8273 , C12N2310/141
摘要： Provided is the miRNA miR1855b.3 which has the nucleotide sequence of SEQ ID NO:l and its precursor and target genes. Also provided is its application in enhancing heat stress response of plants. Downregulation of miR1855b.3, upregulation of its target(s), reducing or eliminating binding of miR1855b.3 to its target(s), and/or reducing or eliminating the cleavage of the target(s) by miR1855b.3 prvide strategies to improve heat tolerance in plants. Furthermore, strategies to downregulate miR1855b.3, upregulate its target(s), to reduce or eliminate binding of miR1855b.3 to its target(s), and/or cleavage of the target(s) by miR1855b.3 are also provided.
摘要翻译：提供具有SEQ ID NO：1的核苷酸序列及其前体和靶基因的miRNA miR1855b.3。还提供其在增强植物的热应激反应中的应用。 miR1855b.3的下调，其靶标的上调，减少或消除miR1855b.3与其靶标的结合，和/或通过miR1855b.3预防策略减少或消除靶标的切割提高植物耐热性。此外，还提供了下调miR1855b.3的上调策略，以减少或消除miR1855b.3与其靶标的结合，和/或miR1855b.3对靶点的切割。

5. 发明申请

WO2011139440A2 LOOSELY-COUPLED ENCRYPTION FUNCTIONALITY FOR OPERATING SYSTEMS 审中-公开
标题翻译：用于操作系统的LOUSELY-COUPLED加密功能
公开(公告)号：WO2011139440A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/030742
申请日：2011-03-31
申请人： SONUS NETWORKS, INC. , BHARRAT, Shaun, Jaikarran , JOACHIMPILLAI, Damascene, M. , KURIAKOSE, Aby , LU, Vivian , YU, Xiang
发明人： BHARRAT, Shaun, Jaikarran , JOACHIMPILLAI, Damascene, M. , KURIAKOSE, Aby , LU, Vivian , YU, Xiang
IPC分类号： H04L29/06
CPC分类号： H04L63/164 , H04L63/0281 , H04L63/06
摘要： Described are computer-based methods and apparatuses, including computer program products, for loosely-coupled encryption functionality for operating systems. A data packet is processed through one or more internet protocol stack layers to generate a processed data packet. Encryption information is determined that includes parameters for encrypting and decrypting data packets transmitted between the first computing device and the remote computer. A message comprising data indicative of the encryption information is transmitted to a second computing device, wherein an operating system being executed is unaware of a security nature of the transmission. A bypass encryption routine is executed to generate a unencrypted data packet, wherein the bypass encryption routine does not encrypt the processed data packet. The unencrypted data packet is transmitted to the second computing device. The unencrypted data packet is encrypted based on the message transmitted from the first computing device to generate an encrypted data packet.
摘要翻译：描述了基于计算机的方法和装置，包括用于操作系统的松散耦合加密功能的计算机程序产品。数据包通过一个或多个互联网协议栈层进行处理，以产生经处理的数据包。确定加密信息，其包括用于加密和解密在第一计算设备和远程计算机之间传输的数据分组的参数。包括指示加密信息的数据的消息被发送到第二计算设备，其中正在执行的操作系统不知道传输的安全性质。执行旁路加密例程以生成未加密的数据分组，其中旁路加密例程不加密经处理的数据分组。未加密的数据分组被发送到第二计算设备。基于从第一计算设备发送的消息来加密未加密的数据分组，以生成加密的数据分组。

6. 发明申请

WO2011090686A2 COATED ABRASIVE BACKINGS WITH CLOTH TREATED WITH COLLOIDAL SILICON OXIDE 审中-公开
标题翻译：用胶体氧化硅处理过的涂层的涂布磨具
公开(公告)号：WO2011090686A2
公开(公告)日：2011-07-28
申请号：PCT/US2010062021
申请日：2010-12-23
申请人： SAINT GOBAIN ABRASIVES INC , SAINT GOBAIN ABRASIFS SA , YANG YU XIANG , SESHU ADISESHAIAH K , FENG LIN HUA
发明人： YANG YU XIANG , SESHU ADISESHAIAH K , FENG LIN HUA
IPC分类号： B24D3/02 , B24D18/00 , C09C1/68 , C09K3/14
CPC分类号： B24D11/02 , B24D3/004 , B24D11/001 , Y10T442/2738
摘要： A cloth backing for an abrasive article is treated by combining a phenolic resin, a latex and a colloidal silicon oxide composition to prepare a colloidal formulation, which is then applied to the cloth backing and cured. Coated abrasive articles are formed by applying a make coat formulation to the treated cloth backing, applying an abrasive and then curing the make coat formulation.
摘要翻译：通过将酚醛树脂，胶乳和胶体氧化硅组合物组合以处理磨料制品的布背衬以制备胶体制剂，然后将其施加到布背衬上并固化。涂覆的磨料制品通过将涂层制剂施加到处理过的布料背衬上，施加研磨剂然后固化该涂层制剂而形成。

7. 发明申请

WO2011088577A1 SYSTEM AND METHOD FOR ENCODING AND DECODING PULSE INDICES 审中-公开
标题翻译：编码和解码脉冲指标的系统和方法
公开(公告)号：WO2011088577A1
公开(公告)日：2011-07-28
申请号：PCT/CA2011/050036
申请日：2011-01-21
申请人： RESEARCH IN MOTION LIMITED , YU, Xiang , HE, Dake , YANG, En-Hui
发明人： YU, Xiang , HE, Dake , YANG, En-Hui
IPC分类号： G10L19/08 , G10L19/12
CPC分类号： G10L19/12 , G10L2019/0007
摘要： Methods and corresponding codec-containing devices are provided that have source coding schemes for encoding a component of an excitation. In some cases, the source coding scheme is an enumerative source coding scheme, while in other cases the source coding scheme is an arithmetic source coding scheme. In some cases, the source coding schemes are applied to encode a fixed codebook component of the excitation for a codec employing codebook excited linear prediction, for example an AMR-WB (Adaptive Multi-Rate - Wideband) speech codec.
摘要翻译：提供了具有用于编码激励分量的源编码方案的方法和相应的编解码器装置。在一些情况下，源编码方案是枚举源编码方案，而在其他情况下，源编码方案是算术源编码方案。在一些情况下，源编码方案被应用于编码采用码本激励线性预测的编解码器的激励的固定码本分量，例如AMR-WB（自适应多速率 - 宽带）语音编解码器。

8. 发明申请

WO2010091505A1 MODIFIED ENTROPY ENCODING FOR IMAGES AND VIDEOS 审中-公开
标题翻译：用于图像和视频的修改的入侵编码
公开(公告)号：WO2010091505A1
公开(公告)日：2010-08-19
申请号：PCT/CA2010/000181
申请日：2010-02-12
申请人： RESEARCH IN MOTION LIMITED , YU, Xiang , HE, Dake , YANG, En-Hui
发明人： YU, Xiang , HE, Dake , YANG, En-Hui
IPC分类号： H04N7/50
CPC分类号： H04N21/2383 , H04N19/117 , H04N19/124 , H04N19/129 , H04N19/13 , H04N19/134 , H04N19/14 , H04N19/154 , H04N19/176 , H04N19/18 , H04N19/82 , H04N19/86 , H04N19/91 , H04N21/4382 , H04N21/8543
摘要： A method and encoder for entropy encoding image data using a dynamically determined coding order, and a method and decoder for entropy decoding encoded data encoded using a dynamically determined coding order. The coding order for encoding quantized transform domain coefficients is dynamically determined for the image based on at least one characteristic of the quantized transform domain coefficients. The characteristic may be quantization step size if non-uniform quantization is employed for blocks of data.
摘要翻译：一种用于使用动态确定的编码顺序对图像数据进行熵编码的方法和编码器，以及用于熵解码使用动态确定的编码顺序编码的编码数据的方法和解码器。基于量化的变换域系数的至少一个特性，动态地为图像动态地确定编码量化的变换域系数的编码顺序。如果对数据块采用非均匀量化，则该特性可以是量化步长。

9. 发明申请

WO2010091503A1 ADAPTIVE QUANTIZATION WITH BALANCED PIXEL-DOMAIN DISTORTION DISTRIBUTION IN IMAGE PROCESSING 审中-公开
标题翻译：图像处理中平衡像素域分布分布的自适应量化
公开(公告)号：WO2010091503A1
公开(公告)日：2010-08-19
申请号：PCT/CA2010/000179
申请日：2010-02-10
申请人： RESEARCH IN MOTION LIMITED , YU, Xiang , HE, Dake , YANG, En-Hui
发明人： YU, Xiang , HE, Dake , YANG, En-Hui
IPC分类号： G06T9/00 , H04N7/50
CPC分类号： H04N19/14 , H04N19/124 , H04N19/147 , H04N19/154 , H04N19/18 , H04N19/61
摘要： Methods and encoders and decoders for adaptively quantizing transform domain coefficients in image and/or video encoding/decoding. For an image having a number of blocks, each block having N coefficients, the quantization step size for each coefficient is selected dynamically, thus resulting in a quantizer that may apply different step sizes to different coefficients. The selected step sizes for each coefficient are used for those coefficients within all blocks in the image/frame. In one aspect, the step sizes are selected on the basis of balancing pixel domain distortion when the image/frame is decoded.
摘要翻译：用于自适应地量化图像和/或视频编码/解码中的变换域系数的方法和编码器和解码器。对于具有多个块的图像，每个块具有N个系数，动态地选择每个系数的量化步长，从而得到量化器，该量化器可以将不同的步长应用于不同的系数。每个系数的所选步长被用于图像/帧中所有块内的那些系数。在一个方面中，在解码图像/帧时平衡像素域失真来选择步长。

10. 发明申请

WO2008157157A3 DROUGHT-RESISTANT PLANTS AND METHOD FOR PRODUCING THE PLANTS 审中-公开
标题翻译：抗旱植物和生产植物的方法
公开(公告)号：WO2008157157A3
公开(公告)日：2009-02-26
申请号：PCT/US2008066495
申请日：2008-06-11
申请人： HELIX D , ZHANG DA-PENG , ZHU SAI-YONG , YU XIANG-CHUN , WANG XIAO-JING , WANG XIAO-FANG
发明人： ZHANG DA-PENG , ZHU SAI-YONG , YU XIANG-CHUN , WANG XIAO-JING , WANG XIAO-FANG
IPC分类号： C12N15/82 , C12N5/04
CPC分类号： C12N15/8273
摘要： This application provides a recombinant expression cassette for expressing CPK4 or CPK11, two calcium-dependent protein kinases found in plants. Also provided are a transgenic plant with heightened ABA-sensitivity and drought-resistance, as well as a method for producing such plants.
摘要翻译：本申请提供了用于表达在植物中发现的两种钙依赖性蛋白激酶的CPK4或CPK11的重组表达盒。还提供了具有高ABA敏感性和抗旱性的转基因植物，以及用于生产这种植物的方法。

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