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1. 发明申请

WO2006045004A9 A SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC INFORMATION OF AN INDIVIDUAL OR POPULATION 审中-公开
标题翻译：获取，存储，处理和利用个人或人口的免疫学信息的系统和方法
公开(公告)号：WO2006045004A9
公开(公告)日：2006-08-24
申请号：PCT/US2005037686
申请日：2005-10-18
申请人： BIOVERIS CORP , MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES Q , COLEMAN DAVID , SHETTY SURAJ , JOSHI KAMINI
发明人： MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES Q , COLEMAN DAVID , SHETTY SURAJ , JOSHI KAMINI
IPC分类号： G06F19/00 , G06F19/18 , G06Q50/24
CPC分类号： G06F19/3456 , G06F19/18 , G06Q50/24 , G16H10/60 , G16H15/00 , G16H50/20 , G16H50/30 , G16H50/80 , Y02A90/22 , Y02A90/24 , Y02A90/26
摘要： A system and method for obtaining, storing, processing and utilizing immunologic information of individuals and populations is presented. In exemplary embodiments of the present invention, a biological sample can be taken from one or more individuals and the sample submitted to one or more panels of assays. The results of the assays can be stored and analyzed, and such analysis can include (i) calculating derived quantities which take the results of the assays as inputs, and (ii) submitting the results and the derived quantities to a set of rules, each of which has a defined output state. In exemplary embodiments of the present invention, based upon the output state of the rules, an appropriate recommendation as to one or more immunization or other interventions can be generated and incorporated with provider and patient reminders. In exemplary embodiments of the present invention the results of the assays and the recommendation, as well as additional information specific to the individual can be stored for further analysis. In exemplary embodiments of the present invention the assay panel or panels can be chosen as a function of a defined demographic group or enterprise affinity into which the individual corresponds. In exemplary embodiments a database can be maintained for storing and further processing of all immunologic informatics collected according to the methods of the present invention, and can be further processed or used to optimize the delivery of products and/or services in various commercial, research and governmental contexts.
摘要翻译：介绍了获取，存储，处理和利用个人和群体免疫学信息的系统和方法。在本发明的示例性实施方案中，可以从一个或多个个体获取生物样品，并将样品提交给一个或多个测定组。测定结果可以被存储和分析，并且这种分析可以包括（i）计算将测定结果作为输入的衍生量，以及（ii）将结果和派生数量提交到一组规则，每个规则其中有一个定义的输出状态。在本发明的示例性实施例中，基于规则的输出状态，可以生成关于一个或多个免疫或其他干预的适当建议，并且与提供者和患者提醒并入。在本发明的示例性实施方案中，可以存储测定和推荐结果以及个体特有的附加信息用于进一步分析。在本发明的示例性实施方案中，测定面板或面板可以作为个体对应的定义的人口统计组或企业亲和力的函数来选择。在示例性实施例中，可以维护数据库以存储和进一步处理根据本发明的方法收集的所有免疫信息，并且可以进一步处理或使用数据库来优化各种商业，研究和/或服务的产品和/或服务的递送政府背景。

2. 发明申请

WO2006045004A3 SYSTEM AND METHOD FOR OBTAINING, STORING, AND PROCESSING IMMUNOLOGIC INFORMATION OF INDIVIDUALS AND POPULATIONS 审中-公开
公开(公告)号：WO2006045004A3
公开(公告)日：2006-04-27
申请号：PCT/US2005/037686
申请日：2005-10-18
申请人： BIOVERIS CORPORATION , MICHON, Francis , MOORE, Samuel, L. , FUSCO, Peter, C. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Q. , COLEMAN, David , SHETTY, Suraj , JOSHI, Kamini
发明人： MICHON, Francis , MOORE, Samuel, L. , FUSCO, Peter, C. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Q. , COLEMAN, David , SHETTY, Suraj , JOSHI, Kamini
IPC分类号： G06F19/00 , G01N33/48
摘要： A system and method for obtaining, storing, and processing immunologic information of individuals and populations is presented. A biological sample can be taken from at least one individual and submitted to one or more panels of assays. The results of the assays can be stored and analyzed, and such analyses include (i) calculating derived quantities which take the results of the assays as inputs, and (ii) submitting the results and the derived quantities to a set of rules, each of which has a defined output state. Based upon the output state of the rules, an appropriate recommendation as to one or more immunization or other interventions can be generated and incorporated with provider and patient reminders. The results of the assays and recommendation, and additional information specific to the individual can be stored for further analysis.

3. 发明申请

WO2009061514A1 AUTOMATED SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC AND OTHER INFORMATION OF AN INDIVIDUAL AND POPULATION FOR VARIOUS USES 审中-公开
标题翻译：自动化系统和获取，存储，处理和使用个体和人口的各种用途的免疫和其他信息的方法
公开(公告)号：WO2009061514A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/012658
申请日：2008-11-10
申请人： 32 MOTT STREET ACQUISITION I, LLC, d/b/a , MICHON, Francis , MOORE, Samuel, L. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , OTERO, Glen , HALEVA, Aaron, S.
发明人： MICHON, Francis , MOORE, Samuel, L. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , OTERO, Glen , HALEVA, Aaron, S.
IPC分类号： G06F17/18 , G06Q50/00
CPC分类号： G01N33/5023 , G06F19/24 , G06F19/28
摘要： A system and method for assessing the immunological status of one or more individuals in a patient population Is presented The method includes establishing a database comprising a plurality of records of information each representative of the immune status of individual in the population, each of said records including (1 ) current information from one or more assays for the presence of a biochemical, and (2) individual specific information compπsing one or more of said individual's medical history, said individual's docto observations and historical, demographic, lifestyle, and familial information relating to said individual The method further includes processing the information in said database to find trends or patterns relating to the immune status of individuals in said pati population, and using the said trends or patterns as part of a health care related decision making process.
摘要翻译：用于评估患者群体中一个或多个个体的免疫状态的系统和方法本方法包括建立数据库，该数据库包括多个代表个体在个体中的免疫状态的信息记录，每个记录包括（1）来自一种或多种用于生物化学物质存在的测定的现有信息，和（2）压制所述个体的病史中的一种或多种的个体特异性信息，所述个体的病历观察和与之相关的历史，人口统计学，生活方式和家族性信息所述个体该方法还包括处理所述数据库中的信息以发现与所述pati群体中的个体的免疫状态相关的趋势或模式，并且将所述趋势或模式用作与保健相关的决策过程的一部分。

4. 发明申请

WO2007127490A3 SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC AND OTHER INFORMATION OF AN INDIVIDUAL OR POPULATION 审中-公开
公开(公告)号：WO2007127490A3
公开(公告)日：2007-11-08
申请号：PCT/US2007/010576
申请日：2007-04-27
申请人： BIOVERIS CORPORATION , MICHON, Francis , MOORE, Samuel, L. , FUSCO, Peter, C. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , COLEMAN, David , SHETTY, Suraj , TRAPATHI, Vinay , JOSHI, Kamini
发明人： MICHON, Francis , MOORE, Samuel, L. , FUSCO, Peter, C. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , COLEMAN, David , SHETTY, Suraj , TRAPATHI, Vinay , JOSHI, Kamini
IPC分类号： G06Q50/00
摘要： A system and method for assessing the immunological status of one or more individuals in a patient population is presented. The method includes establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, each of said records including (1 ) current information from one or more assays for the presence of a biochemical, and (2) individual specific information comprising one or more of said individual's medical history, said individual's doctors; observations and historical, demographic, lifestyle, and familial information relating to said individual. The method further includes processing the information in said database to find trends or patterns relating to the. immune status of individuals in said patient population; and using the said trends or patterns as part of a health care related decision making process.

5. 发明申请

WO2007127490A2 SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC AND OTHER INFORMATION OF AN INDIVIDUAL OR POPULATION 审中-公开
标题翻译：用于获取，存储，处理和使用个体或人口的免疫和其他信息的系统和方法
公开(公告)号：WO2007127490A2
公开(公告)日：2007-11-08
申请号：PCT/US2007010576
申请日：2007-04-27
申请人： BIOVERIS CORP , MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES QUENTIN , COLEMAN DAVID , SHETTY SURAJ , TRAPATHI VINAY , JOSHI KAMINI
发明人： MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES QUENTIN , COLEMAN DAVID , SHETTY SURAJ , TRAPATHI VINAY , JOSHI KAMINI
IPC分类号： G06Q10/00 , G06Q50/00
CPC分类号： G06Q10/00 , G06F19/18 , G06F19/24 , G06Q50/22 , Y02A90/22 , Y02A90/24 , Y02A90/26
摘要： A system and method for assessing the immunological status of one or more individuals in a patient population is presented. The method includes establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, each of said records including (1) current information from one or more assays for the presence of a biochemical, and (2) individual specific information comprising one or more of said individual's medical history, said individual's doctors' observations and historical, demographic, lifestyle, and familial information relating to said individual. The method further includes processing the information in said database to find trends or patterns relating to the. immune status of individuals in said patient population; and using the said trends or patterns as part of a health care related decision making process. In exemplary embodiments of the present invention, processing the information in the database includes generating a list of correlations between variables or fields in the database, and for each correlation in the list generating a set of hypotheses that may explain said correlation. In exemplary embodiments of the present invention, as to each hypothesis in the set, automatically refuting, supporting or stating that there is insufficient data to analyze said hypothesis by further processing of the database; and reporting the correlations, their associated hypotheses and the refutation, support, or determination of insufficient data to refute or support, to a user.
摘要翻译：提出了一种用于评估患者群体中一个或多个个体的免疫状态的系统和方法。该方法包括建立数据库，该数据库包括多个代表个体在个体中的免疫状态的信息记录，每个所述记录包括（1）来自一个或多个生物化学物质存在的测定的当前信息，和 2）个体特定信息，其包括所述个人的病史，所述个人的医生观察以及与所述个人有关的历史，人口，生活方式和家庭信息中的一个或多个。该方法还包括处理所述数据库中的信息以找出与该数据库有关的趋势或模式。个体在所述患者群体中的免疫状态; 并将所述趋势或模式用作与保健相关的决策过程的一部分。在本发明的示例性实施例中，处理数据库中的信息包括生成数据库中的变量或字段之间的相关性的列表，以及生成可以解释所述相关性的一组假设中的每个相关。在本发明的示例性实施例中，关于集合中的每个假设，通过进一步处理数据库自动驳斥，支持或指出没有足够的数据来分析所述假设; 并向用户报告相关性，相关假设以及不足数据的反驳，支持或确定。

6. 发明申请

WO2006045004A2 A SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC INFORMATION OF AN INDIVIDUAL OR POPULATION 审中-公开
标题翻译：一种获取，储存，处理和利用个体或人群的免疫信息的系统和方法
公开(公告)号：WO2006045004A2
公开(公告)日：2006-04-27
申请号：PCT/US2005037686
申请日：2005-10-18
申请人： BIOVERIS CORP , MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES Q , COLEMAN DAVID , SHETTY SURAJ , JOSHI KAMINI
发明人： MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES Q , COLEMAN DAVID , SHETTY SURAJ , JOSHI KAMINI
IPC分类号： G06F19/00 , G06F19/18 , G06Q50/24
CPC分类号： G06F19/3456 , G06F19/18 , G06Q50/24 , G16H10/60 , G16H15/00 , G16H50/20 , G16H50/30 , G16H50/80 , Y02A90/22 , Y02A90/24 , Y02A90/26
摘要： A system and method for obtaining, storing, processing and utilizing immunologic information of individuals and populations is presented. In exemplary embodiments of the present invention, a biological sample can be taken from one or more individuals and the sample submitted to one or more panels of assays. The results of the assays can be stored and analyzed, and such analysis can include (i) calculating derived quantities which take the results of the assays as inputs, and (ii) submitting the results and the derived quantities to a set of rules, each of which has a defined output state. In exemplary embodiments of the present invention, based upon the output state of the rules, an appropriate recommendation as to one or more immunization or other interventions can be generated and incorporated with provider and patient reminders. In exemplary embodiments of the present invention the results of the assays and the recommendation, as well as additional information specific to the individual can be stored for further analysis. In exemplary embodiments of the present invention the assay panel or panels can be chosen as a function of a defined demographic group or enterprise affinity into which the individual corresponds. In exemplary embodiments a database can be maintained for storing and further processing of all immunologic informatics collected according to the methods of the present invention, and can be further processed or used to optimize the delivery of products and/or services in various commercial, research and governmental contexts.
摘要翻译：介绍了获取，存储，处理和利用个体和种群免疫信息的系统和方法。在本发明的示例性实施方案中，可以从一个或多个个体获取生物样品，并将样品提交给一个或多个测定小组。可以存储和分析测定结果，并且这样的分析可以包括（i）计算将测定结果作为输入的导出量，以及（ii）将结果和导出的数量提交给一组规则，每个其中有一个确定的输出状态。在本发明的示例性实施例中，基于规则的输出状态，可以生成关于一种或多种免疫或其他干预的适当推荐，并与提供者和患者提醒结合。在本发明的示例性实施例中，可以存储测定和推荐的结果以及个体特有的附加信息以供进一步分析。在本发明的示例性实施例中，可以根据个体对应的限定的人口统计学群体或企业亲和度来选择一个或多个分析面板。在示例性实施方案中，可以维持数据库用于存储和进一步处理根据本发明的方法收集的所有免疫信息学，并且可以进一步处理或用于优化各种商业，研究和/或服务中的产品和/或服务的递送政府环境。

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