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1. 发明申请

WO2010074837A1 METHOD FOR REDUCTION OF MICROBES ON SURFACES 审中-公开
标题翻译：减少表面微量元素的方法
公开(公告)号：WO2010074837A1
公开(公告)日：2010-07-01
申请号：PCT/US2009/064603
申请日：2009-11-16
申请人： GENERAL ELECTRIC COMPANY , WHITEKETTLE, Wilson, Kurt , JIANG, Juan , HUANG, Xudong
发明人： WHITEKETTLE, Wilson, Kurt , JIANG, Juan , HUANG, Xudong
IPC分类号： C02F1/50 , A01N55/10
CPC分类号： C02F1/50 , A01N55/00 , C02F1/44 , C02F2103/08 , C02F2303/08 , C02F2303/20 , Y02A20/131 , A01N25/30
摘要： A method has been found for the removal of microbial biofilm on surfaces in contact with systems, including but not limited to aqueous systems, which comprises adding to the aqueous system an effective amount of a polyalkyleneoxide polysiloxane surfactant to substantially remove microbial biofilm, from surfaces in aquatic systems, while presenting minimal danger to non-target aquatic organisms at discharge due to their very low discharge concentrations.
摘要翻译：已经发现一种在与系统接触的表面上去除微生物生物膜的方法，包括但不限于水性体系，其包括向水性体系中加入有效量的聚环氧烷聚硅氧烷表面活性剂以从微生物生物膜中的表面水体系统，由于其非常低的排放浓度，对非目标水生生物排放的危险最小。

2. 发明申请

WO2009020694A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS 审中-公开
标题翻译：用于控制水质体系中微生物生物学的方法
公开(公告)号：WO2009020694A1
公开(公告)日：2009-02-12
申请号：PCT/US2008/065197
申请日：2008-05-30
申请人： GENERAL ELECTRIC COMPANY , WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean , ZHAO, Qing
发明人： WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean , ZHAO, Qing
IPC分类号： C02F1/50 , C02F1/68
CPC分类号： C02F1/50 , A01N47/44 , A01N47/48 , C02F2303/20 , C02F2305/14 , Y10S210/916 , A01N25/04 , A01N2300/00
摘要： A process has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, therein removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks. According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the exiting biofilm. Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or programmed disintegration of the liposome proceeds Thereafter the biocidal aqueous core is released to react directh with the biofilm encased microorganisms. Upon the death of the organisms, the polysaccharide/prolem matrix decomposes and thereby results in reduced fouling of the water bearing system, resulting in increased heat transfer, increased flux, less deposit of colloidal and particulate solids and dissolved orgamcs on the surface of the microfillration membrane. thereby reducing the frequenev and duration of the membrane cleaning and ultimate replacement.
摘要翻译：已经发现了一种通过使用脂质体载体将抗微生物化合物引入到复杂生物膜基质中的效率和有效性的方法，其中除去工业含水系统中的生物污垢，包括管道，热交换，冷凝器，过滤系统和流体储存罐。根据本发明的一个实施方案，将含抗微生物化合物的脂质体加入容易生物结垢和生物膜形成的水体系中。与微生物膜或细胞组成相似的脂质体容易并入到离开的生物膜中。一旦包含脂质体的抗微生物化合物变得与生物膜基质夹带，则脂质体的分解或程序分解进行到此之后，释放出杀生物的水性核与生物膜包裹的微生物直接反应。当生物体死亡时，多糖/原料基质分解，从而导致含水系统的结垢减少，导致增加的热传递，增加的通量，较少的胶体和颗粒固体的沉积物和微量的表面上的溶解的有机物膜。从而降低膜清洗的频率和持续时间并最终更换。

3. 发明申请

WO2010120568A1 METHOD FOR REMOVING MICROBES FROM SURFACES 审中-公开
标题翻译：从表面除去微生物的方法
公开(公告)号：WO2010120568A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/029576
申请日：2010-04-01
申请人： GENERAL ELECTRIC COMPANY , WHITEKETTLE, Wilson, Kurt , PENG, Wenqing , LU, Su , JIANG, Juan
发明人： WHITEKETTLE, Wilson, Kurt , PENG, Wenqing , LU, Su , JIANG, Juan
IPC分类号： A61L2/18 , A01N25/30 , A01N25/32 , C11D1/82 , B08B9/08 , B08B3/04
CPC分类号： A61L2/18 , A01N55/00
摘要： A method has been found for the removal of microbial bio film on surfaces in contact with systems, including but not limited to aqueous systems, which comprises adding to the aqueous system an effective amount of a carbosilane-based surfactant to substantially remove microbial biofilm, from surfaces in aquatic systems, while presenting minimal danger to non-target aquatic organisms at discharge due to their very low discharge concentrations.
摘要翻译：已经发现一种在与系统接触的表面上除去微生物生物膜的方法，包括但不限于水性体系，其包括向水性体系中加入有效量的基于碳硅烷的表面活性剂以基本上除去微生物生物膜，从水体系中的表面，同时由于其非常低的排放浓度，对非目标水生生物排放的危险最小。

4. 发明申请

WO2010107533A1 BIODELIVERY SYSTEMS 审中-公开
标题翻译：生物系统
公开(公告)号：WO2010107533A1
公开(公告)日：2010-09-23
申请号：PCT/US2010/023973
申请日：2010-02-12
申请人： GENERAL ELECTRIC COMPANY , WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean , MURPHY, Kimberly , ZHAO, Qing
发明人： WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean , MURPHY, Kimberly , ZHAO, Qing
IPC分类号： A01N47/44 , A01N47/48 , C02F1/50
CPC分类号： C02F1/50 , A01N25/28 , A01N25/34 , A01N33/12 , A01N35/08 , A01N43/80 , A01N59/26 , A01N37/34
摘要： A biodelivery system has been found which increases the efficiency and effectiveness of introducing anti microbial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing s\ stems, including piping, heat exchanges, condensers, filtration s> stems and fluid storage tanks According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or disintegration of the liposome proceeds Thereafter the biocidal core is released to react directly with the biofilm encased microorganisms. Upon the death of the organisms, the matrix decomposes and thereby results m reduced fouling of the water bearing system, resulting in increased heat transfer, increased flux, less deposit of colloidal and particulate solids and dissolved organics on the surface of the microfiltration membrane, thereby reducing the frequency and duration of the membrane cleaning and ultimate replacement
摘要翻译：已经发现生物输送系统通过使用脂质体载体而增加了将抗微生物化合物引入复杂生物膜基质的效率和有效性，从而消除了工业含水的生物污垢，包括管道，热交换器，冷凝器，过滤器 >茎和液体储存罐根据本发明的一个实施方案，将含抗微生物化合物的脂质体加入易于生物结垢和生物膜形成的水体系中。组成与微生物膜或细胞相似的脂质体容易并入现有的生物膜中含有脂质体的抗微生物化合物变得与生物膜基质夹带，脂质体的分解或分解进行。然后将杀生物核心释放直接与生物膜包裹的微生物反应。在生物体死亡时，基质分解，从而导致含水系统的结垢减少，导致增加的热传递，增加的通量，较少的胶体和颗粒固体的沉积以及溶解的有机物沉积在微滤膜的表面上，由此降低膜清洗的频率和持续时间并最终更换

5. 发明申请

WO2012083497A1 METHODS OF REMOVING MICROBES FROM SURFACES 审中-公开
标题翻译：从表面除去微生物的方法
公开(公告)号：WO2012083497A1
公开(公告)日：2012-06-28
申请号：PCT/CN2010002123
申请日：2010-12-22
申请人： GEN ELECTRIC , JIANG JUAN , MELZER JEFFREY I , WHITEKETTLE WILSON KURT , ZHANG GUIXI , ZHAO QING
发明人： JIANG JUAN , MELZER JEFFREY I , WHITEKETTLE WILSON KURT , ZHANG GUIXI , ZHAO QING
IPC分类号： C02F1/50
CPC分类号： C02F1/50 , C02F2103/023 , C02F2209/06 , C02F2303/20
摘要： A method has been found for the inhibition of microbial biofilm on surfaces in contact with systems, such as aqueous systems. In accordance with the method, an effective amount of a modified starch polymer is fed to the system water. The modified starch polymer may be a cationic quaternary ammonium starch.
摘要翻译：已经发现在与系统接触的表面上抑制微生物生物膜的方法，例如水系统。按照该方法，向系统水中加入有效量的改性淀粉聚合物。改性淀粉聚合物可以是阳离子季铵淀粉。

6. 发明申请

WO2012044409A1 METHOD FOR CONTROLLING MICROBIAL BIOFILM IN AQUEOUS SYSTEMS 审中-公开
标题翻译：用于控制水质体系中微生物生物学的方法
公开(公告)号：WO2012044409A1
公开(公告)日：2012-04-05
申请号：PCT/US2011/048341
申请日：2011-08-19
申请人： GENERAL ELECTRIC COMPANY , WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean , ZHAO, Qing , WANG, Linna , REYNOLDS, Dorothy , FRAIL, Paul , JIANG, Juan , POLIZZOTI, David, M.
发明人： WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean , ZHAO, Qing , WANG, Linna , REYNOLDS, Dorothy , FRAIL, Paul , JIANG, Juan , POLIZZOTI, David, M.
IPC分类号： C02F1/50 , A01N25/28 , A01N47/44 , A01N47/46 , A01N25/32
CPC分类号： C02F1/50 , A01N47/44 , A01N47/48 , C02F2303/04 , C02F2303/20 , C02F2305/04 , C02F2305/14 , A01N25/04 , A01N2300/00
摘要： A process has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks. According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm. Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or programmed disintegration of the liposome proceeds. Thereafter, the biocidal aqueous core is released to react directly with the biofilm encased microorganisms. Upon the death of the organisms, the polysaccharide/protein matrix decomposes and thereby results in reduced fouling of the water bearing system, resulting in increased heat transfer, increased flux, less deposit of colloidal and particulate solids and dissolved organics on the surface of the microfiltration membrane, thereby reducing the frequency and duration of the membrane cleaning and ultimate replacement.
摘要翻译：已经发现了一种通过使用脂质体载体将抗微生物化合物引入复合生物膜基质的效率和有效性的方法，从而消除工业含水系统中的生物污垢，包括管道，热交换器，冷凝器，过滤系统和流体储存罐。根据本发明的一个实施方案，将含抗微生物化合物的脂质体加入容易生物结垢和生物膜形成的水体系中。与微生物膜或细胞组成相似的脂质体容易并入现有的生物膜中。一旦包含脂质体的抗微生物化合物变得与生物膜基质夹带，就可以进行脂质体的分解或程序分解。此后，释放杀生物的水性核心直接与生物膜包裹的微生物反应。当生物体死亡时，多糖/蛋白质基质分解，从而导致含水系统的结垢减少，导致增加的热传递，增加的通量，较少的胶体和颗粒固体的沉积以及溶解的有机物在微量过滤表面上膜，从而降低膜清洗的频率和持续时间并最终更换。

7. 发明申请

WO2009020689A1 METHOD FOR CONTROLLING PROTOZOA THAT HARBOR BACTERIA 审中-公开
标题翻译：控制细菌菌株的方法
公开(公告)号：WO2009020689A1
公开(公告)日：2009-02-12
申请号：PCT/US2008/065047
申请日：2008-05-29
申请人： GENERAL ELECTRIC COMPANY , WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean
发明人： WHITEKETTLE, Wilson, Kurt , TAFEL, Gloria, Jean
IPC分类号： A01N25/28 , A01P1/00
CPC分类号： A01N25/28 , Y10S514/963 , A01N33/12 , A01N47/44 , A01N57/20
摘要： A method for controlling protozoa trophozites and cysts wherein biocides or control agents are encapsulated within microcapsules or manufactured into the core of liposomes, thereafter the biocide containing microcapsules or liposomes are then introduced into an aqueous system.
摘要翻译：一种用于控制原生动物滋养细胞和囊肿的方法，其中将杀生物剂或控制剂包封在微胶囊内或制成脂质体核心，然后将含有微胶囊或脂质体的杀生物剂引入含水体系中。

8. 发明申请

WO2012083497A8 METHODS OF REMOVING MICROBES FROM SURFACES 审中-公开
公开(公告)号：WO2012083497A8
公开(公告)日：2012-06-28
申请号：PCT/CN2010/002123
申请日：2010-12-22
申请人： GENERAL ELECTRIC COMPANY , JIANG, Juan , MELZER, Jeffrey , WHITEKETTLE, Wilson Kurt , ZHANG, Guixi , ZHAO, Qing
发明人： JIANG, Juan , MELZER, Jeffrey , WHITEKETTLE, Wilson Kurt , ZHANG, Guixi , ZHAO, Qing
IPC分类号： C02F1/50
摘要： A method has been found for the inhibition of microbial biofilm on surfaces in contact with systems, such as aqueous systems. In accordance with the method, an effective amount of a modified starch polymer is fed to the system water. The modified starch polymer may be a cationic quaternary ammonium starch.

9. 发明申请

WO2012083496A1 METHODS OF REMOVING MICROBES FROM SURFACES 审中-公开
标题翻译：从表面除去微生物的方法
公开(公告)号：WO2012083496A1
公开(公告)日：2012-06-28
申请号：PCT/CN2010/002122
申请日：2010-12-22
申请人： GENERAL ELECTRIC COMPANY , JIANG, Juan , MELZER, Jeffrey, I. , WHITEKETTLE, Wilson, Kurt , ZHANG, Guixi , ZHAO, Qing
发明人： JIANG, Juan , MELZER, Jeffrey, I. , WHITEKETTLE, Wilson, Kurt , ZHANG, Guixi , ZHAO, Qing
IPC分类号： C02F1/50
CPC分类号： A01N65/00 , A01N61/00 , C02F1/441 , C02F1/50 , C02F1/54 , C02F2103/023 , C02F2303/20 , A01N25/10
摘要： A method has been found for the inhibition of microbial biofilm on surfaces in contact with systems, such as aqueous systems. In accordance with the method, an effective amount of a modified tannin biofilm control agent is fed to the system water. The modified tannin biofilm control agent comprises a reaction product of an amine, an aldehyde and tannin and provides a good environmental profile.
摘要翻译：已经发现在与系统接触的表面上抑制微生物生物膜的方法，例如水系统。根据该方法，将有效量的改性单宁生物膜控制剂加入系统水中。修饰的单宁生物膜控制剂包括胺，醛和单宁的反应产物，并提供良好的环境特性。

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