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1. 发明申请

WO2011043859A1 ROTATIONAL ATHERECTOMY DEVICE WITH KEYED EXCHANGEABLE DRIVE SHAFT 审中-公开
标题翻译：具有钥匙可交换驱动轴的旋转自行车装置
公开(公告)号：WO2011043859A1
公开(公告)日：2011-04-14
申请号：PCT/US2010/044216
申请日：2010-08-03
申请人： CARDIOVASCULAR SYSTEMS, INC. , WELTY, Ryan D.
发明人： WELTY, Ryan D.
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B17/32 , A61B17/3207 , A61B2017/0046 , A61B2017/00477 , A61B2017/00486
摘要： An atherectomy device with an exchangeable drive shaft is disclosed, having a mechanical coupling that can allow for axial translation of the drive shaft while keeping the drive shaft rotationally locked to the prime mover. The coupling is geometrically keyed, with one side of the coupling having an aperture with a particular internal cross-section, and the other side of the coupling having an external cross-section that matches all or a part of the corresponding internal cross-section. Key shapes may be hexagonal, square, n-sided polygonal, star-shaped, or any other suitable shape. The keys may optionally include one or more rounded corners to simplify manufacturing. Axial motion may be locked by an optional twist-lock connection of two elements that surround the keyed coupling.
摘要翻译：公开了一种具有可更换驱动轴的粥样斑块切除装置，其具有能够使驱动轴旋转地锁定到原动机上的驱动轴的轴向平移的机械联接。联接器几何地键合，耦合器的一侧具有具有特定内部横截面的孔，并且联接器的另一侧具有匹配相应内部横截面的全部或一部分的外部横截面。关键形状可以是六边形，正方形，n边多边形，星形或任何其他合适的形状。键可以可选地包括一个或多个圆角以简化制造。可以通过围绕键合联接器的两个元件的可选扭锁连接来锁定轴向运动。

2. 发明申请

WO2011103069A1 DEVICES AND METHODS FOR LOW SHEARING LOCAL DELIVERY OF THERAPEUTIC AGENTS TO THE WALL OF A BODILY LUMEN 审中-公开
标题翻译：治疗方法低剂量局部输送给身体壁的设备和方法
公开(公告)号：WO2011103069A1
公开(公告)日：2011-08-25
申请号：PCT/US2011/024839
申请日：2011-02-15
申请人： CARDIOVASCULAR SYSTEMS, INC. , SCHOENLE, Victor Leo , WELTY, Ryan, D. , TIBESAR JENSEN, Kristina , PIIPPO SVENDSEN, Cassandra Ann , MCBROOM, Jeffrey, A.
发明人： SCHOENLE, Victor Leo , WELTY, Ryan, D. , TIBESAR JENSEN, Kristina , PIIPPO SVENDSEN, Cassandra Ann , MCBROOM, Jeffrey, A.
IPC分类号： A61M25/10
CPC分类号： A61M25/1011 , A61M25/0029 , A61M25/0662 , A61M25/104 , A61M2025/0018 , A61M2025/0681 , A61M2025/1013 , A61M2025/105
摘要： The invention relates generally to devices and methods for local delivery of therapeutic agents to the wall of a bodily lumen with minimal shearing damage to the therapeutic agents, more specifically to the wall of a blood vessel following atherectomy. A preferred delivery mechanism comprises a balloon, or double balloon, though any distal catheter design may be used to reduce shear stress and to conserve and/or isolate the therapeutic substance.
摘要翻译：本发明一般涉及用于将治疗剂局部递送到体腔壁的装置和方法，其具有对治疗剂的最小的剪切损伤，更具体地涉及粥样斑块切除术后的血管壁。优选的输送机构包括球囊或双气囊，尽管任何远端导管设计可用于降低剪切应力并保护和/或分离治疗物质。

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